The derivative as a rate of change. Differentiation of elementary, trigonometric, exponential, and logarithmic functions. The definite integral as a summation. Integration. The Fundamental Theorem of Calculus. Applications in the context of the life sciences. Prerequisite: Mathematics 30-1. Note: Credit can be obtained in at most one of MATH 100, 113, 114, 117, 134, 144, 154 or SCI 100.