Area of Study / Keywords
chronic pain opioid dependence addiction inflammation gut microbiome hyperalgesia affective disorders affective disorders reward motivated behaviour animal models
Dr. Taylor strives to understand how chronic pain and opioids impact emotional brain regions. Her research explores how these changes contribute to pain and whether they alter opioid efficacy. She explores strategies to improve the efficacy of opioids while minimizing abuse liability. Finally, she studies non-canonical opioid agonists to treat pain without abuse liability. This research comes at a critical juncture when safe and effective chronic pain management is increasingly challenging amidst the opioid overdose epidemic. Outcomes from this program will develop strategies for safe and effective opioid prescribing, and identify novel targets for the treatment of chronic pain.
Dentistry Course 1 (Intro to Pharmacology)
Using examples of commonly used drugs (both therapeutic and illicit), we will explore what drugs do to the human body and in turn, what the body does to drugs. Recommended for students with an interest in pursuing medical science degrees and programs. Prerequisites: CHEM 101 and BIOL 107 or equivalent. Open to 2nd and 3rd year students only.
The influence of the gut microbiota during opioid withdrawal
International Narcotic Research Conference. 2022 July;
Claustral-prefrontal cortical control of acute and chronic pain
Canadian Neuroscience Annual Meeting. 2022 May;
Galleguillos D., Wang Q., Steinberg N., Zaidi A., Shrivastava G., Dhami K., Daskhan G.C., Schmidt E.N., Dworsky-Fried Z., Giuliani F., Churchward M., Power C., Todd K., Taylor A., Macauley M.S., Sipione S.
Journal of Neuroinflammation. 2022 January; 19 (1) 10.1186/s12974-021-02374-x
Taylor A.M.W., Chadwick C.I., Mehrabani S., Hrncir H., Arnold A.P., Evans C.J.
JOURNAL OF NEUROSCIENCE RESEARCH. 2022 January; 100 (1):183-190 10.1002/jnr.24704
Zoë Dworsky-Fried, Caylin I Chadwick, Bradley J Kerr, Anna M W Taylor
Frontiers in Neuroscience. 2021 September; 10.3389/fnins.2021.741503
Amygdala control of EAE related pain
International Narcotic Research Conference. 2021 July;
Zoë Dworsky-Fried, Christian A Faig, Holly A Vogel, Bradley J Kerr, Anna M W Taylor
PAIN. 2021 April; 10.1097/j.pain.0000000000002307