Bo Cao

Area of Study / Keywords

Computational Psychiatry Machine Learning Mental Disorders Precision Medicine in Mental Health Brain Imaging Brain Maturation and Aging

---

About

Trained in mathematics (BSc), psychology (MSc), computational neuroscience (PhD), neuroimaging and psychiatry (postdoc), I have a strong passion for understanding the fundamental mechanisms of how the brain works and how to cure the brain when the mechanisms are disturbed. As the Canada Research Chair in Computational Psychiatry (Tier 2), I am always seeking young talents to work with as graduate students (Masters and PhD) and postdoctoral fellows, who have a passion to learn more about the brain and mental disorders and to use their analytical expertise to help patients and clinicians. Prospective lab members must be team players with strong interest in data-driven research in mental health using multimodal neuroimaging, genetic, cognition, electronic health and administrative data. Please feel free to contact me if you are interested in joining our interdisciplinary group or collaborations.

My main research interests are:

1) Computational psychiatry and precision medicine in mental health. I hope to develop translational tools that can provide accurate and personalized diagnosis and treatment optimization for mental disorders. This can be achieved by identifying objective biomarkers associated with mental disorders and their treatment outcomes through multimodal data including brain imaging, genetic, biological, behavioral, cognitive and clinical measurements, and by applying advanced machine learning and statistical algorithms to these data.

2) Brain development and aging. Our brain is a very plastic organ that changes over the lifespan. It is necessary to consider the brain development and aging and associated cognitive change, when we investigate brain disorders. I am interested in lifespan structural and functional changes of the brain, developing personalized tools of brain development and aging, and applying these tools to the brain with mental disorders.

3) Neuromodulation and neurofeedback.

DeMaster D., Godlewska B., Liang M., Vannucci M., Bockmann T., Bo C., Selvaraj S.

JOURNAL OF AFFECTIVE DISORDERS. 2022 June; 307 10.1016/j.jad.2022.03.041

---

Psychiatry Research Day - University of Alberta . 2022 June;

---

Benoit J.R.A., Dursun S.M., Greiner R., Cao B., Brown M.R.G., Lam R.W., Greenshaw A.J.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE. 2022 June; 67 (1):39-47 10.1177/07067437211037141

---

Psychiatry Research Day - University of Alberta . 2022 June;

---

Psychiatry Research Day - University of Alberta . 2022 June;

---

Yang S. Liu, Jeffrey R. Hankey, Stefani Chokka, Pratap R. Chokka, Bo Cao

Scientific Reports. 2022 June; 12 (1):9599 https://doi.org/10.1038/s41598-022-13642-y

---

Al-Shamali H., Hussain A., Dennett L., Cao B., Burback L., Greenshaw A., Zhang Y.

Journal of Affective Disorders Reports. 2022 May; 9 10.1016/j.jadr.2022.100356

---

Obuobi-Donkor G., Eboreime E., Bond J., Phung N., Eyben S., Hayward J., Zhang Y., MacMaster F., Clelland S., Greiner R., Jones C., Cao B., Brémault-Phillips S., Wells K., Li X.M., Hilario C., Greenshaw A.J., Agyapong V.I.O.

JMIR Research Protocols. 2022 April; 11 (4) 10.2196/30680

---

Yankouskaya A., Denholm-Smith T., Yi D., Greenshaw A.J., Cao B., Sui J.

Frontiers in Systems Neuroscience. 2022 April; 16 10.3389/fnsys.2022.833625

---

Eboreime E., Shalaby R., Mao W., Owusu E., Vuong W., Surood S., Bales K., MacMaster F.P., McNeil D., Rittenbach K., Ohinmaa A., Bremault-Phillips S., Hilario C., Greiner R., Knox M., Chafe J., Coulombe J., Xin-Min L., McLean C., Rathwell R., Snaterse M., Spurvey P., Taylor V.H., McLean S., Urichuk L., Tzeggai B., McCabe C., Grauwiler D., Jordan S., Brown E., Fors L., Savard T., Grunau M., Kelton F., Stauffer S., Cao B., Chue P., Abba-Aji A., Silverstone P., Nwachukwu I., Greenshaw A., Agyapong V.I.O.

BMC HEALTH SERVICES RESEARCH. 2022 March; 22 (1) 10.1186/s12913-022-07510-8

---

Wang Y., Zhou X., Cao B., Chen L., Wang R., Qi L., Meng L., Zeng L., Liu X., Wang W., Li C., Yang J., Gu X., Li Z., Zhou Y.

JOURNAL OF AFFECTIVE DISORDERS. 2022 February; 298 10.1016/j.jad.2021.10.130

---

Lang X., Wang D., Chen D., Xiu M., Zhou H., Wang L., Cao B., Zhang X.

Neurotherapeutics. 2022 January; 19 (1):399-407 10.1007/s13311-021-01174-8

---

Sämann P.G., Iglesias J.E., Gutman B., Grotegerd D., Leenings R., Flint C., Dannlowski U., Clarke-Rubright E.K., Morey R.A., van Erp T.G.M., Whelan C.D., Han L.K.M., van Velzen L.S., Cao B., Augustinack J.C., Thompson P.M., Jahanshad N., Schmaal L.

HUMAN BRAIN MAPPING. 2022 January; 43 (1):207-233 10.1002/hbm.25326

---

Liu Y.S., Chokka S., Cao B., Chokka P.R.

Journal of Affective Disorders Reports. 2021 December; 6 10.1016/j.jadr.2021.100215

---

Forgie E.M.E., Lai H., Cao B., Stroulia E., Greenshaw A.J., Goez H.

JOURNAL OF MEDICAL INTERNET RESEARCH. 2021 December; 23 (12) 10.2196/25230

---

Cao B., Liu Y.S., Selvitella A., Librenza-Garcia D., Passos I.C., Sawalha J., Ballester P., Chen J., Dong S., Wang F., Kapczinski F., Dursun S.M., Li X.M., Greiner R., Greenshaw A.

Scientific Reports. 2021 October; 11 (1) 10.1038/s41598-021-99534-z

---

Sui J., Greenshaw A.J., Macrae C.N., Cao B.

JOURNAL OF AFFECTIVE DISORDERS. 2021 October; 293 10.1016/j.jad.2021.06.041

---

Zhang Q., He H., Cao B., Gao R., Jiang L., Zhang X., Dai J.

NEUROSCIENCE LETTERS. 2021 August; 760 10.1016/j.neulet.2021.136084

---

Jeffrey Sawalha, Muhammad Yousefnezhad, Alessandro M. Selvitella, Bo Cao, Andrew J. Greenshaw & Russell Greiner

Scientific Reports. 2021 August; 11 10.1038/s41598-021-98957-4

---

Tannous J., Cao B., Stanley J.A., Zunta-Soares G.B., Mwangi B., Sanches M., Soares J.C.

MOLECULAR PSYCHIATRY. 2021 August; 26 (8):4117-4126 10.1038/s41380-020-00927-9

---

Chang M., Womer F.Y., Gong X., Chen X., Tang L., Feng R., Dong S., Duan J., Chen Y., Zhang R., Wang Y., Ren S., Wang Y., Kang J., Yin Z., Wei Y., Wei S., Jiang X., Xu K., Cao B., Zhang Y., Zhang W., Tang Y., Zhang X., Wang F.

MOLECULAR PSYCHIATRY. 2021 July; 26 (7):3003 10.1038/s41380-020-00938-6

---

Antonelli-Salgado T., Monteiro G.M.C., Marcon G., Roza T.H., Zimerman A., Hoffmann M.S., Cao B., Hauck S., Brunoni A.R., Passos I.C.

JOURNAL OF AFFECTIVE DISORDERS. 2021 July; 290 10.1016/j.jad.2021.04.044

---

Jabbari-zadeh F., Cao B., Stanley J.A., Liu Y., Wu M.J., Tannous J., Lopez M., Sanches M., Mwangi B., Zunta-Soares G.B., Soares J.C.

JOURNAL OF AFFECTIVE DISORDERS. 2021 June; 289 10.1016/j.jad.2021.04.011

---

Nunez J.J., Nguyen T.T., Zhou Y., Cao B., Ng R.T., Chen J., Frey B.N., Milev R., Müller D.J., Rotzinger S., Soares C.N., Uher R., Kennedy S.H., Lam R.W.

PLoS One. 2021 June; 16 (6 June) 10.1371/journal.pone.0253023

---

Wei G.X., Ge L., Chen L.Z., Cao B., Zhang X.

HUMAN BRAIN MAPPING. 2021 April; 42 (6):1617-1625 10.1002/hbm.25315

---

Shalaby R., Vuong W., Hrabok M., Gusnowski A., Mrklas K., Li D., Snaterse M., Surood S., Cao B., Li X.M., Greiner R., Greenshaw A.J., Agyapong V.I.O.

JMIR mHealth and uHealth. 2021 April; 9 (4) 10.2196/24184

---

Sawalha J., Cao L., Chen J., Selvitella A., Liu Y., Yang C., Li X., Zhang X., Sun J., Zhang Y., Zhao L., Cui L., Zhang Y., Sui J., Greiner R., Li X.m., Greenshaw A., Li T., Cao B.

JOURNAL OF AFFECTIVE DISORDERS. 2021 March; 282 10.1016/j.jad.2020.12.046

---

Agyapong V.I.O., Shalaby R., Hrabok M., Vuong W., Noble J.M., Gusnowski A., Mrklas K., Li D., Snaterse M., Surood S., Cao B., Li X.M., Greiner R., Greenshaw A.J.

International Journal of Environmental Research and Public Health. 2021 February; 18 (4):1-13 10.3390/ijerph18042157

---

Nkire N., Mrklas K., Hrabok M., Gusnowski A., Vuong W., Surood S., Abba-Aji A., Urichuk L., Cao B., Greenshaw A.J., Agyapong V.I.O.

Frontiers in Psychiatry. 2021 February; 12 10.3389/fpsyt.2021.553468

---

Hong S., Liu Y.S., Cao B., Cao J., Ai M., Chen J., Greenshaw A., Kuang L.

JOURNAL OF AFFECTIVE DISORDERS. 2021 February; 280 10.1016/j.jad.2020.10.077

---

Zhou H., Wang D., Wang J., Xu H., Cao B., Zhang X.

Asian Journal of Psychiatry. 2021 January; 10.1016/j.ajp.2021.102749

---

Xiu M.H., Lang X., Chen D.C., Cao B., Kosten T.R., Cho R.Y., Shi H., Wei C.W., Wu A.S., Zhang X.Y.

CEREBRAL CORTEX. 2021 January; 31 (1):89-96 10.1093/cercor/bhaa208

---

Camkurt M.A., Melicher T., Mwangi B., Wu M.J., Cao B., Zeni C.P., Tannous J., Zunta-Soares G., Hasan K., Sanches M., Soares J.C.

CNS SPECTRUMS. 2021 January; 10.1017/S1092852921000584

---

Yang D., Chen J., Cheng X., Cao B., Chang H., Li X., Yang C., Wu Q., Sun J., Manry D., Pan Y., Dong Y., Li J., Xu T., Cao L.

DEPRESSION AND ANXIETY. 2021 January; 10.1002/da.23186

---

Agyapong V.I.O., Hrabok M., Shalaby R., Vuong W., Noble J.M., Gusnowski A., Mrklas K., Li D., Urichuck L., Snaterse M., Surood S., Cao B., Li X.M., Greiner R., Greenshaw A.J.

Disaster Medicine and Public Health Preparedness. 2021 January; 10.1017/dmp.2021.27

---

Benoit J.R.A., Dursun S.M., Greiner R., Cao B., Brown M.R.G., Lam R.W., Greenshaw A.J.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE. 2021 January; 10.1177/07067437211037141

---

Agyapong V.I.O., Hrabok M., Vuong W., Shalaby R., Noble J.M., Gusnowski A., Mrklas K.J., Li D., Urichuk L., Snaterse M., Surood S., Cao B., Li X.M., Greiner R., Greenshaw A.J.

JMIR Mental Health. 2020 December; 7 (12) 10.2196/22423

---

Song Y., Talarico F., Greenshaw A., Cao B.

JOURNAL OF AFFECTIVE DISORDERS. 2020 December; 277 10.1016/j.jad.2020.09.048