Biological Specimen Banks Translational Medical Research Serine Proteases COVID-19 Angioedema Hemoglobinopathies Genetic Therapy Iron
I am a professor of Medicine in Hematology at the University of Alberta where I established clinical research, and comprehensive care/home treatment programs in bleeding, angioedema, immunodeficiencies, Porphyria, and hemoglobinopathies. I built a large biobank for translational research; and basic research programs in gene therapy, protein structure-function, novel anticoagulants, iron metabolism, and bio-surveillance, including Covid-19. I serve on numerous patient and physician organizations for which I received a Lifetime Achievement Award from the Canadian Hemophilia Society; a Diamond Jubilee medal from the Governor-General of Canada; the Leonard Tow Award for Humanism from the Arnold Gold Foundation, and was made a Fellow of the Royal College of Physicians of Edinburgh in 2018. I have published with my three sons and somehow remain married to 9-time Triathlon and Duathlon world champion, Margie Ritchie, although I cannot keep up with her. I consider myself very, very lucky.
I work in clinical medicine, clinical research and basic research with a particular interest in translational research or bringing basic research to the clinic. At the University of Alberta and Walter Mckenzie Health Sciences Centre, I am director of the Canadian Biosample Repository, the Thromboembolism clinic, Bleeding Disorder & Rare Blood Disorder Clinic, and the Medical Outpatient unit at the UofA Hospital. I do clinical research in bleeding, thromboembolism, hemoglobinopathies, hereditary and idiopathic angioedema, immunodeficiency disorders, porphyria, blood-borne pathogens and Covid-19. The biobank serves as a tool for researchers to collect samples for later study. This has been a boon during the Covid-19 pandemic. My basic research lab has worked on gene therapy, structure-function studies in recombinant blood clotting proteins, novel anticoagulants, iron metabolism, bio-surveillance, and biobanking of human and agricultural samples. Currently, I am using molecular modelling to work on protein complex formation between serine proteases.
CoCollab is now collecting samples from people getting Covid-19 vaccines.