Carolyn Fitzsimmons

Contact

Faculty of Agricultural, Life and Environmental Sci - Ag, Food & Nutri Sci Dept
Email
cfitzsim@ualberta.ca

Overview

About

Degree

PhD, Uppsala University, Sweden

Job/Research Area  

Gene Expression, Bovine Genetics 


Research

Major Responsibilities/Research Interests 

My interests lie in how biological systems influence the development of lean meat and fat tissues, specifically looking through the window of gene expression. Many new and exciting areas have now come to the forefront regarding the control of gene expression via dietary means (nutrigenomics), and the different individual responses to changes in diet (nutrigenetics). By utilizing changes in gene expression due to diet and/or other treatments, we can tease out a clearer understanding of how biological systems function and then apply this knowledge to practical situations, for example beef production. I am also interested permanent gene expression changes that can be programmed in the next generation due to nutrition and/or other factors affecting the parental generation (epigenetics). 

Courses

AFNS 574 - Applied Beef Cattle Science

Examination of current and potential future production and management practices to optimize production efficiency and animal well-being in the Canadian and international beef industry. Laboratories emphasize practical applications, field trips, and discussion. Not to be taken if credit received for AN SC 474. Prerequisite: consent of instructor.

Winter Term 2021
AN SC 474 - Applied Beef Cattle Science

Examination of current and potential future production and management practices to optimize production efficiency and animal well-being in the Canadian and international beef industry. Laboratories emphasize practical applications, field trips, and discussion. Prerequisites: (AN SC 101 or 200), AN SC 260 and AN SC 310.

Winter Term 2021

Browse more courses taught by Carolyn Fitzsimmons

Publications

Genome-wide association for heifer reproduction and postpartum performance traits in beef cattle
Author(s): Akanno EC, Plastow G, Fitzsimmons C,Akanno EC, Plastow G, Fitzsimmons C, Miller SP, Baron V, Ominski K, Basarab JA
Publication Date: 2015
Publication: Genome

Transcriptomic analysis by RNA-sequencing reveals that hepatic interferon-induced genes may be associated with feed efficiency in beef heifers
Author(s): Paradis F, Yue S, Grant JR, Stothard P, Basarab J, & Fitzsimmons C
Publication Date: 2015
Publication: Journal of Animal Science
Volume: 93
Issue: 7
Page Numbers: 3331-3341

Characterization and evaluation of residual feed intake measured in mid- to late-gestation mature beef cows and relationships with circulating serum metabolites and linear body measurements
Author(s): Wood KM, Montanholi YR, Fitzsimmons CF, Miller SP, McBride BW, & Swanson KC
Publication Date: 2014
Publication: Canadian Journal of Animal Science
Volume: 94
Issue: 3
Page Numbers: 499-508

Widespread Differential Maternal and Paternal Genome Effects on Fetal Bone Phenotype at Mid-Gestation
Author(s): Xiang R, Lee AMC, Eindorf T, Javadmanesh A, Ghanipoor-Samami M, Gugger M, Fitzsimmons CJ, Kruk ZA, Pitchford WS, Leviton AJ, Thomsen DA, Beckman I, Anderson GI, Burns BM, Rutley DL, Xian CJ, Hiendleder S
Publication Date: 2014
Publication: Journal of Bone and Mineral Research
Volume: 29
Issue: 11
Page Numbers: 2392-2404

Effect of moderate dietary restriction on visceral organ weight, hepatic oxygen consumption, and metabolic proteins associated with energy balance in mature pregnant beef cows
Author(s): Wood KM, Awda BJ, Fitzsimmons C, Miller SP, McBride BW, & Swanson KC
Publication Date: 2013
Publication: Journal of Animal Science
Volume: 91
Issue: 9
Page Numbers: 4245-4255

Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at Midgestation
Author(s): Xiang R, Ghanipoor-Samami M, Johns WH, Eindorf T, Rutley DL, Kruk ZA, Fitzsimmons C, Thomsen DA, Roberts CT, Burns BM, Anderson GI, Greenwood PL, & Hiendleder S
Publication Date: 2013
Publication: PLoS One
Volume: 8
Issue: 1
Page Numbers: e53402

The influence of pregnancy in mid-to-late gestation on circulating metabolites, visceral organ mass, and abundance of proteins relating to energy metabolism mature beef cows
Author(s): Wood KM, Awda BJ, Fitzsimmons C, Miller SP, McBride BW, & Swanson KC
Publication Date: 2013
Publication: Journal of Animal Science
Volume: 91
Issue: 12
Page Numbers: 5775-5784

INSL3 in the Ruminant: A Powerful Indicator of Gender- and Genetic-Specific Feto-Maternal Dialogue
Author(s): Anand-Ivell R., Hiendleder S., Viñoles C., Martin G.B., Fitzsimmons C., Eurich A., Hafen B. & Ivell R.
Publication Date: 2011
Publication: PLoS One
Volume: 6
Page Numbers: e19821

Extremely different behaviours in high and low body weight lines of chicken are involved in differential expression of genes involved in neuronal plasticity
Author(s): S. Ka, J. Lindberg, L. Stömstedt, C. J. Fitzsimmons, N. Lindqvist, J. Lundeberg, P.B. Siegel, L. Andersson, and F. Hallböök
Publication Date: 2009
Publication: J Neuroendocrinol
Volume: 21
Page Numbers: 208-216

A cis-acting regulatory mutation is causing premature hair greying and susceptibility to melanoma in the horse
Author(s): G. Rosengren-Pielberg, A. Golovko, E. Sundström, I. Curik, J. Lennartsson, M. H. Seltenhammer, T. Druml, M. Binns, C. Fitzsimmons, G. Lindgren, K. Sandberg, R. Baumung, M. Vetterlein, S. Strömberg, M. Grabherr, C. Wade, K. Lindblad-Toh1, F. Pontén, C. Heldin, J. Sölkner and L. Andersson
Publication Date: 2008
Publication: Nature Genetics
Volume: 40
Page Numbers: 1004-1009

Differential gene expression in femoral bone from red junglefowl and domestic chicken, differing for bone phenotypic traits
Author(s): C-J. Rubin, J. Lindberg, C. J. Fitzsimmons, P. Savolainen, P. Jensen, J. Lundeberg, L. Andersson, A. Kindmark
Publication Date: 2007
Publication: BMC Genomics
Volume: 8
Page Numbers: 208

ESTs from brain and testis of White Leghorn and red junglefowl: annotation, bioinformatic classification of unknown transcripts and analysis of expression levels
Author(s): P. Savolainen, C. J. Fitzsimmons, L. Arvestad, L. Andersson, and J. Lundeberg
Publication Date: 2005
Publication: Cytogenet. Genome Res.
Volume: 111
Page Numbers: 79-87

Expression analysis of growth and energy regulation-associated genes in two divergent chicken strains
Author(s): S. Ka, C. J. Fitzsimmons, L. Jacobsson, P. Savolainen, J. Lundeberg, P.B. Siegel, L. Andersson, and F. Hallböök
Publication Date: 2005
Publication: Ann. N Y Acad. Sci.
Volume: 1040
Page Numbers: 357-359

Detection of sequence polymorphisms in red junglefowl and White Leghorn ESTs
Author(s): C. J. Fitzsimmons, P. Savolainen, B. Amini, G. Hjälm, J. Lundeberg, and L. Andersson
Publication Date: 2004
Publication: Anim. Genet.
Volume: 35
Page Numbers: 391-396

Complementary DNA macroarray analyses of differential gene expression in porcine fetal and postnatal muscle
Author(s): S-H. Zhao, D. Nettleton, W. Liu, C. Fitzsimmons, C. W. Ernst, N. E. Raney, and C. K. Tuggle
Publication Date: 2003
Publication: J. Anim. Sci.
Volume: 81
Page Numbers: 2179-2188

EST-Based Gene Discovery in Pig: Virtual Expression Patterns and Comparative Mapping to Human
Author(s): C. K. Tuggle, J. A. Green, C. Fitzsimmons, R. Woods, R. S. Prather, S. Malchenko, M. B. Soares, T. Kucaba, K. Crouch, C. Smith, D. Tack, N. Robinson, B. O'Leary, T. Scheetz, T. Casavant, D. Pomp, J. B. Edeal, Y. Zhang, M. F. Rothschild, and K. G. Beavis
Publication Date: 2003
Publication: Mamm. Genome
Volume: 14
Page Numbers: 565-579

Association of a missense mutation in the bovine leptin gene with carcass fat content and leptin mRNA levels
Author(s): F. C. Buchanan, C. J. Fitzsimmons, A. G. Van Kessel, T. D. Thue, D.C. Winkelmen-Sim and S. M. Schmutz
Publication Date: 2002
Publication: Genet. Sel. Evol.
Volume: 34
Page Numbers: 105-116

Precise mapping of breakpoints in conserved synteny between human chromosome 1 and pig chromosomes 4, 6 and 9
Author(s): H. S. Sun, C. K. Tuggle, A. Goureau, C. J. Fitzsimmons, P. Pinton, P. Chardon and M. Yerle
Publication Date: 2002
Publication: Anim. Genet.
Volume: 33
Page Numbers: 91-96

Radiation hybrid comparative mapping between human chromosome 17 and porcine chromosome 12 demonstrates conservation of gene order
Author(s): X-W. Shi, C. J. Fitzsimmons, C. Genêt, R. Prather, K. Whitworth, J. A. Green, and C. K. Tuggle
Publication Date: 2001
Publication: Anim. Genet.
Volume: 32
Page Numbers: 205-209

A potential association between the BM 1500 microsatellite and fat deposition in cattle
Author(s): C. J. Fitzsimmons, S. M. Schmutz, R. D. Bergen, and J. J. McKinnon
Publication Date: 1998
Publication: Mamm. Genome
Volume: 9
Page Numbers: 432-434