Daniel Barreda

Area of Study / Keywords

Immunology; animal health; host-pathogen-environment interactions

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About

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Research

Current Research Interests

My laboratory examines immunity as a critical node in the relationship between hosts, pathogens, and the environment. We look for immunological successes across evolution, and apply them to improve human and animal health, and decrease our impact on the environment. Our strengths are in primary cell culture, in vivo infection models, behavioural analyses, and functional evaluation of immune responses.

Projects are often inter- or trans- disciplinary with collaborations across academia, industry, and government. Over the years, our studies have offered important insights into antimicrobial protection, inflammation control, and wound repair. They have also provided novel bioindicators of health which we continue to apply to infection disease control, nutritional studies, and environmental risk assessments.

I hold appointments in the Department of Biological Sciences, and the Department of Agriculture, Food and Nutritional Science at the University of Alberta.

Representative projects:1) Fever as an evolutionary conserved mediator of health.2) Improved health and performance in cold-blooded animals through dynamic temperature control.3) A natural antibiotic alternative for decreased pathogen spread and enhanced coastal and marine ecosystem health.4) Promoting resilience of coastal communities through sustainable fish production.

AFNS 511 - Veterinary Immunology

Application of immunological principles to the understanding of animal health and disease with a focus on livestock and companion animals. Students will apply a broad understanding of host-pathogen interactions and the basic mechanisms of disease progression to assess the short and long-term impact of pathogenesis to the health of animals, their caretakers, and consumers. Lectures will be followed by active discussion of selected readings. Not to be taken if credit received for AN SC 411. Prerequisites: IMIN 200 and consent of instructor.

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AN SC 411 - Veterinary Immunology

Application of immunological principles to the understanding of animal health and disease with a focus on livestock and companion animals. Students will apply a broad understanding of host-pathogen interactions and the basic mechanisms of disease progression to assess the short and long-term impact of pathogenesis to the health of animals, their caretakers, and consumers. Lectures will be followed by active discussion of selected readings. Prerequisite: IMIN 200 or AN SC 375.

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BIOL 409 - Zoonoses

This course will examine the biology of zoonotic agents and the implication of host-pathogen interactions to disease susceptibility and resistance. Students will apply these basic concepts towards the understanding of issues governing pathogenesis, pathology, epidemiology, control and surveillance of zoonotic diseases. Focus will be placed on zoonotic agents currently having a significant impact on animal and public health. Lectures will be followed by active discussion of selected readings. Prerequisites: one of IMIN 200, ZOOL 352, ZOOL 354, or ENT 392. Credit cannot be obtained for both BIOL 409 and BIOL 509.

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BIOL 509 - Advanced Topics in Zoonoses

This course will examine the biology of zoonotic agents and the implication of host-pathogen interactions to disease susceptibility and resistance. Students will apply these basic concepts towards the understanding of issues governing pathogenesis, pathology, epidemiology, control and surveillance of zoonotic diseases. Focus will be placed on zoonotic agents currently having a significant impact on animal and public health. Lectures will be followed by active discussion of selected readings. Scheduled classes are the same as for BIOL 409, but with additional assignments and evaluation appropriate to graduate studies. Prerequisite: consent of instructor. Credit cannot be obtained for both BIOL 409 and BIOL 509.

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IMIN 405 - Innate Immunity

This course covers topics of innate immunity with emphasis on strategies for pathogen recognition, local and systemic activation of the innate immune response, and regulation of innate effector mechanisms. Innate defense strategies against pathogens as well as detection and elimination of tumors will also be covered. Lectures will be followed by active discussions of selected readings pertaining to current research in the subject area. Prerequisites: IMIN 371. Credit cannot be obtained for both IMIN 405 and 505. (Offered jointly by the Departments of Biological Sciences and Medical Microbiology and Immunology). [Biological Sciences].

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IMIN 505 - Advanced Innate Immunity

This course covers topics of innate immunity with emphasis on strategies for pathogen recognition, local and systemic activation of the innate immune response, and regulation of innate effector mechanisms. Innate defense strategies against pathogens as well as detection and elimination of tumors will also be covered. Lectures will be followed by active discussions of selected readings pertaining to current research in the subject area. Lectures and graded discussions are the same as for IMIN 405 but with evaluation appropriate for graduate students. Prerequisites: consent of instructor. Credit cannot be obtained for both IMIN 405 and 505. (Offered jointly by the Departments of Biological Sciences and Medical Microbiology and Immunology). [Biological Sciences].

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Browse more courses taught by Daniel Barreda

Rieger AM, Konowalchuk JD, Grayfer L, Katzenback BA, Havixbeck JJ, Kiemele MD, Belosevic M, Barreda DR

PLoS ONE. 2012 January; 7 (10)

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Parra D, Rieger AM, Li J, Zhang Y-A, Randall LM, Hunter CA, Barreda DR, Sunyer JO

Journal of Leukocyte Biology. 2012 January; 91 (4):525

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Rieger AM, Barreda DR

Developmental and Comparative Immunology. 2011 January; 35 (12):1238-1245

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Hamidu JA, Uddin Z, Fasenko GM, Guan LL, Barreda DR

Poultry Science. 2011 January; 90 (8):1749-1757

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Rieger AM, Nelson KL, Konowalchuk JD, Barreda DR

Journal of Visualized Experiments. 2011 January; (50):2597

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Rieger AM, Hall BE, Barreda DR

Developmental and Comparative Immunology. 2010 January; 34 (11):1144

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Hamidu JA, Rieger AM, Fasenko GM, Barreda DR

Poultry Science. 2010 January; 89 (5):901-909

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Barreda DR, Rieger AM, Girard NC, Clarahan SDG, Eleyinmi AF

Encyclopedia of Life Support Systems (EOLSS). 2009 January;

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Hanington PC, Tam J-Y, Katzenback BA, Hitchen SJ, Barreda DR, Belosevic M

Developmental and Comparative Immunology. 2009 January; 33 (4):411-429

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Khaniya B, Almeida L, Basu U, Taniguchi M, Williams JL, Barreda DR, Moore SS, Guan LL

Journal of Toxicology and Environmental Health, Part A. 2009 January; 72 (17):1008-1013

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Walsh JG, Barreda DR, Belosevic M

Fish and Shellfish Immunology. 2007 January; 22

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Belosevic M, Hanington PC, and Barreda DR

Fish and Shellfish Immunology. 2006 January; 20 (2):152-171

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Huang Z-Y, Barreda DR, Worth R.G., Kim M-K, Chien P., Indik Z.K., Schreiber A.D.

Journal of Leukocyte Biology. 2006 January; 80 (6):1553-1562

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Hanington PC, Barreda DR, Belosevic M

Journal of Biological Chemistry 14. 2006 January; 281 (15):9963-9970

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Li J., Barreda DR, Zhang YA, Boshra H, Gelman AE, Lapatra S, Tort L, Sunyer JO

Nature Immunology. 2006 January; 7 (10):1116-1124

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Barreda DR, Hanington PC, Stafford JL, Belosevic M

Developmental and Comparative Immunology. 2005 January; 29 (10):879-894

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reda DR, Hanington PC, Walsh CK, Wong P, Belosevic, M

Developmental and Comparative Immunology. 2004 January; 28 (7-8):727-746

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Barreda DR, Hanington PC, Belosevic M

Developmental and Comparative Immunology. 2004 January; 28 (5):509-554

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Barreda DR

Crossing Boundaries (eJournal of the Graduate Students' Association, University of Alberta). 2002 January; 1 (2):99-111

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Barreda DR, Belosevic M

Fish and Shellfish Immunology. 2001 January; 11

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Neumann NF, Stafford JL, Barreda DR, Ainsworth AJ, Belosevic M

Developmental and Comparative Immunology. 2001 January; 25 (8-9):807-825

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Barreda DR, Belosevic M

Developmental and Comparative Immunology. 2001 January; 25 (8-9):763-789.

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Neumann NF, Barreda DR, Belosevic M

Fish and Shellfish Immunology. 2000 January; 10 (1):1-20

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Barreda DR, Neumann NF, Belosevic M

Developmental and Comparative Immunology. 2000 January; 24 (4):395-406

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Ausio J, Soley JT, Burger W, Lewis JD, Barreda D, Cheng KM

Biochemistry. 1999 January; 38 (1):180-184

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Neumann NF, Barreda D, Belosevic M

Developmental and Comparative Immunology. 1998 January; 22 (4):417-432.

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Ausio J, Van Veghel MLJ, Gomez R, Barreda D

Journal of Molecular Evolution. 1997 January; 45

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Hamidu JA, Fasenko GM, Guan LL, Barreda DR, and Feddes JJR

Poultry Science. 90 (2):426-434

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Rieger AM, Hall BE, Luong le T, Schang LM, Barreda DR

Journal of Immunological Methods. 358 (1-2):81-92