Debbie McKenzie, PhD

Associate Professor, Faculty of Science - Biological Sciences

Contact

Associate Professor, Faculty of Science - Biological Sciences
Phone
(780) 248-1721
Address
1-30 Brain And Aging Research Building
8710 - 112 St NW
Edmonton AB
T6G 2M8

Overview

Research
The major research focus of my lab is chronic wasting disease (CWD), a prion disease affecting deer, elk and moose. Prions are unique pathogenic agents, consisting primarily, if not solely, on misfolded conformations of a normal host protein. We are using a number of different model systems, ranging from cell-free to cell culture to primary neuronal cultures to whole lab animals, to address questions regarding the etiology and pathogenesis of CWD. Research is performed in the state-of-the-art Centre for Prions and Protein Folding Diseases. My research focuses on: 1) the role of Prnp genetics on susceptibility to prion infection, 2) CWD strains, 3) role of metals in prion infection, 4) prion disease intra- and inter-species transmission and 5) development of biomarkers for prion diseases.

Courses

BIOL 298 - Understanding Biological Research

An introduction to the process of scientific research including the different approaches to research within biology, formulating research questions, hands-on skill development, experimental design, data collection and analysis, critical thinking, communication of findings, ethics, and career opportunities. Students will attend lectures and selected seminars, and participate in biological research under the supervision of an academic staff member in the Department of Biological Sciences. Open to undergraduate students in the Faculty of Science with preference given to students in Honors and Specialization Programs in the Department of Biological Sciences, and BSc General students (Biological Sciences major). Consent of Department of Biological Sciences required. All students must apply for admission. Prerequisite: BIOL 107 or 108 or SCI 100. See the Biological Sciences website for more details at www.biology.ualberta.ca/courses.

Fall Term 2020
BIOL 642 - Seminars in Physiology, Cell and Developmental Biology

Credit may be obtained more than once.

Fall Term 2020 Winter Term 2021