Contact
Faculty of Medicine & Dentistry - Oncology Dept
- dezanche@ualberta.ca
- Phone
- (780) 989-8155
Overview
Area of Study / Keywords
Electrical Engineering Image-guided Radiation Therapy Magnetic Resonance Imaging radio frequency RF coils
About
Awards:
- Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine, 2018-11-30
Professional Credentials
- Board Certification (MCCPM, 2009): Member of the Canadian College of Physicists in Medicine (CCPM)
- Professional Engineer (P.Eng., 2011): Association of Professional Engineers and Geoscientists of Alberta (APEGA)
- Senior Member (SMIEEE, 2015): Institute of Electrical and Electronics Engineers (IEEE)
Leadership Roles
- ISMRM Working Group on Best Practices for Safety Testing of Experimental RF Hardware (Founder and Chair: 2018-). See published guidelines below. https://www.ismrm.org/working-groups/best-practices-for-safety-testing-of-experimental-rf-hardware/
Research
Magnetic Resonance Instrumentation
My research program aims to improve magnetic resonance imaging (MRI) technology and enhance not only the imaging performance (e.g., signal-to-noise ratio (SNR), resolution, speed) but also safety and patient experience. The following are recent examples, with references to the Featured Publications below.
Advanced Receiver Coils and Arrays
Image SNR is directly related to the quality of the detectors (coils) used to acquire the MR signal. We have developed receive coil arrays for various applications including
- MR-guided focused ultrasound (Proc. ISMRM 2022, p. 1087)
- Linac-MR (3,4; Proc. ISMRM 2019, p. 1589)
- High-field MR (6,7; Proc. ISMRM 2017, p. 4415)
We have also expanded the understanding of coil interactions in an array (14) and verified experimentally the benefits of "3D" coils (11).
RF Safety
The RF power deposited in the body during MRI scanning causes heating and is quantified by the specific absorption rate (SAR). Some aspects of RF safety are always included in RF coil design and construction. We have also explored specific RF safety projects, including developing an inexpensive, modular SAR monitor (Proc. ISMRM 2017, p. 2627) for site-built scanners to ensure SAR remains below the safety thresholds defined by national and international standards.
Application of Metamaterials in MRI
Metamaterials are artificial periodic structures engineered to exhibit values of electromagnetic permittivity and permeability that are not achievable with natural materials. In this ongoing collaborative effort, we have demonstrated the use of RF metamaterials to design body excitation coils (1,2). While performance is similar to that of the standard "birdcage" resonator, the metamaterial body coil also provides much better SAR performance and is suitable for use at the higher frequencies of high-field MRI.
Teaching
ONCOL 556 (Laboratory in Imaging): instructor
ONCOL 560 (Technology in Radiation Oncology): course coordinator and instructor
ONCOL 690 (Biomedical Magnetic Resonance Methods and Applications): course coordinator and instructor
ONCOL 691 (Advanced Magnetic Resonance Physics): instructor
Courses
ONCOL 560 - Technology in Radiation Oncology
Explore the use of technology and physics principles in the diagnosis, tumour and normal tissue delineation, treatment planning, treatment delivery, and treatment verification as applied to cancer patients. Consent of Department required.
Featured Publications
Hybrid 3T 8-channel Receive Array Using a Metamaterial Slab and Companion Loop Elements: Comparison to a Conventional Array
Proceedings of the International Society for Magnetic Resonance in Medicine, 30th annual meeting. 2022 May;
Modular, 3D Printed, Open-source Phantoms for Small Animal Systems
Proceedings of the International Society for Magnetic Resonance in Medicine, 30th annual meeting. 2022 May;
Transmit Performance of a Metamaterial Slab as a Passive RF Shimming Element for 3T MRI
Proceedings of the International Society for Magnetic Resonance in Medicine, 30th annual meeting. 2022 May;
Using a Large-volume, Lightweight, Modular MRI Phantom with Solid Signal Sources
Proceedings of the International Society for Magnetic Resonance in Medicine, 30th annual meeting. 2022 May;
Water-Immersed 8-Dipole Receive Array for MR-Guided Focused Ultrasound of the Brain at 3T
Proceedings of the International Society for Magnetic Resonance in Medicine, 30th annual meeting. 2022 May;
Maunder A.M., Iyer A.K., De Zanche N.
IEEE Access. 2022 January; 10 10.1109/ACCESS.2022.3167764
Maunder A.M., Barker C., De Zanche N., Iyer A.K.
IEEE Access. 2022 January; 10 10.1109/ACCESS.2022.3167432
Puddu C., Rao M., Xu X., Deppe M.H., Collier G., Maunder A., Chan H.F., De Zanche N., Robb F., Wild J.M.
MAGNETIC RESONANCE IN MEDICINE. 2021 December; 86 (6):3373-3381 10.1002/mrm.28915
Design and Modelling of Metamaterial Resonators for 3 Tesla Magnetic Resonance Imaging
International Applied Computational Electromagnetics Society (ACES) Symposium. 2021 August;
2021 International Conference on Electromagnetics in Advanced Applications, ICEAA 2021. 2021 August; 10.1109/ICEAA52647.2021.9539696
Metamaterial liner RF head coil for 23Na and 1H at 4.7 T
Proceedings of the International Society for Magnetic Resonance in Medicine, 29th annual meeting. 2021 May;
Whole-body metamaterial liner RF coil for 1H at 4.7 T with reduced SAR compared to birdcage coil
Proceedings of the International Society for Magnetic Resonance in Medicine, 29th annual meeting. 2021 May;
Barta R., Volotovskyy V., Wachowicz K., Fallone B.G., De Zanche N.
MAGNETIC RESONANCE IN MEDICINE. 2021 April; 85 (4):2327-2333 10.1002/mrm.28540
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