Shokrollah Elahi

Professor, Faculty of Medicine & Dentistry - Dentistry Dept


Professor, Faculty of Medicine & Dentistry - Dentistry Dept
(780) 492-1336
7020G Katz Group Centre For Research
11315 - 87 Ave NW
Edmonton AB
T6G 2H5


Area of Study / Keywords

HIV pathogenesis Cancer Immunotherapy Immunoregulation Immune checkpoints Neonatal immunology Microbiome Cancer


Shokrollah Elahi joined the School in 2014. He obtained several degrees from the Tehran University of Medical Sciences, Iran, and his PhD in Immunology from the Newcastle University in Australia. Elahi moved to Canada and did his first post-doctoral fellowship at Vaccine and Infectious Disease Organization (VIDO) followed by the second post-doctoral fellowship at the Center for Infectious Diseases Research affiliated with the University of Washington (Seattle). Later on as a staff scientist, he continued his research in HIV/AIDS pathogenesis. Finally, he moved to The Cincinnati Children's Hospital Medical Centre where he investigated the mechanism underlying the susceptibility of neonates to infectious diseases.


Dr. Shokrollah Elahi is a cellular and molecular immunologist who works on viral pathogenesis, immune regulation and immune system development.
His research is focused on understanding mechanisms underlying immune dysregulation to generate protective therapeutic approaches. 
The Elahi lab works on different immune cells but his lab is, in particular, interested in CD8 T cells and why these cells become exhausted in the context of chronic viral infections (e.g. HIV) and cancer.  So, Dr. Elahi is working on coaxing the immune system to fight back again tumour cells. His lab works on different types of cancers including viral-associated and non-viral associated solid tumours, and hematological malignancies. 

Featured Publications

Shahbaz S., Okoye I., Blevins G., Elahi S.

PLoS Pathogens. 2022 March; 18 (3) 10.1371/journal.ppat.1010378

Elahi S.

Cellular and Molecular life Sciences . 2022 March; 79 (3) 10.1007/s00018-022-04220-6

Dunsmore G., Rosero E.P., Shahbaz S., Santer D.M., Jovel J., Lacy P., Houston S., Elahi S.

PLOS BIOLOGY. 2021 August; 19 (8) 10.1371/journal.pbio.3001387

Shahbaz S., Xu L., Sligl W., Osman M., Bozorgmehr N., Mashhouri S., Redmond D., Rosero E.P., Walker J., Elahi S.

The Journal of Immunology. 2021 August; 207 (4):1099-1111 10.4049/jimmunol.2100446

Shahbaz S., Xu L., Osman M., Sligl W., Shields J., Joyce M., Tyrrell D.L., Oyegbami O., Elahi S.

Stem Cell Reports . 2021 May; 16 (5):1165-1181 10.1016/j.stemcr.2021.04.001

Clinical and Translational Immunology. 2021 May; 10 (5):e1289

Bozorgmehr N., Mashhouri S., Rosero E.P., Xu L., Shahbaz S., Sligl W., Osman M., Kutsogiannis D.J., Macintyre E., O’neil C.R., Elahi S.

mBio. 2021 April; 12 (3) 10.1128/mBio.00384-21

Bozorgmehr N., Okoye I., Oyegbami O., Xu L., Fontaine A., Cox-Kennett N., Larratt L.M., Hnatiuk M., Fagarasanu A., Brandwein J., Peters A.C., Elahi S.

Journal for Immunotherapy of Cancer . 2021 April; 9 (4) 10.1136/jitc-2020-002189

Okoye I., Xu L., Motamedi M., Parashar P., Walker J.W., Elahi S.

Journal for Immunotherapy of Cancer . 2020 December; 8 (2) 10.1136/jitc-2020-001849

Shokrollah Elahi, James M. Ertelt, Jeremy M. Kinder, Tony T. Jiang, Xuzhe Zhang, Lijun Xin, Vandana Chaturvedi, Beverly S. Strong, Joseph E. Qualls, Kris A. Steinbrecher, Theodosia A. Kalfa, Aimen F. Shaaban & Sing Sing Way

Nature. 2013 November; 504

Shokrollah Elahi, Toshiro Niki, Mitsuomi Hirashima, Helen Horton

Blood. 2012 May; 119 (18):4192-4204. 10.1182/blood-2011-11-389585

Shokrollah Elahi, Warren L Dinges, Nicholas Lejarcegui, Kerry J Laing, Ann C Collier, David M Koelle, M Juliana McElrath & Helen Horton

Nature Medicine . 2011 July; 17