Julianne Gibbs-Davis
Contact
Associate Professor, Faculty of Science - Chemistry
- gibbsdav@ualberta.ca
- Phone
- (780) 492-7140
- Address
-
E3-52A Chemistry Centre - East
11227 Saskatchewan Drive NWEdmonton ABT6G 2G2
Overview
About
BA Arizona State University
PhD Northwestern University
Research
Molecular Recognition at Buried Solid/Liquid Interfaces
Many systems, from the cellular environment to biosensors and heterogeneous catalysis, involve noncovalent interactions between species in solution and those confined to a membrane or solid. Directly monitoring such binding events is difficult because few techniques are sensitive to interactions at an interface and are instead overwhelmed by the sea of molecules in the bulk. However, using surface specific nonlinear optical techniques such as second harmonic generation (SHG) and sum frequency generation (SFG), we can selectively observe interfacial binding allowing us to characterize the thermodynamic and kinetic parameters governing these processes without the use of bulky labels, in situ and in real time.
Courses
CHEM 351 - Introduction to Chemical Biology
Introduction to chemical strategies used to analyze and manipulate biochemical systems. Topics may include chemical synthesis of biopolymers, protein-small molecule interactions, chemoenzymatic synthesis, enzyme-inhibitor kinetics, assay design, characterization of bioorganic samples, and various chemical biology methods. Prerequisites: CHEM 263 or 265; BIOCH 200. Students who have obtained credit for CHEM 451 cannot take CHEM 351 for credit.