Directory

Grant Kemp, PhD

/Grant/

Research Partner, VPRI Research Partner Network

Pronouns: he/him/his

Curriculum Vitæ
Contact Overview Publications Links

Contact

Research Partner, VPRI Research Partner Network
Email
grant.kemp@ualberta.ca
Phone
(780) 492-3397
Address
5-217 Centennial Ctr For Interdisciplinary SCS II
11335 Saskatchewan Drive NW
Edmonton AB
T6G 2H5
Availability
Book an appointment here: https://calendar.app.google/A6fB5tcv7pSn5Kc5A

Overview

Area of Study / Keywords

Biochemistry Biophysics Protein Chemistry Molecular Biology Structural Biochemistry

About

I am currently the Research Partner supporting researchers in the Faculty of Science as well as all researchers applying for international funding opportunities such as:

  • Horizon Europe
  • NSERC Alliance International (Catalyst and Collaborator)
  • Mitacs Globalink
  • NFRF International and Joint calls
  • other international NSE opportunities (e.g. NSF)


Research

My interest in research was really sparked by my introduction to metabolism in high school biology. I was fascinated by the complexity of metabolic networks as well as how enzymes and transporters worked in balance to create, store, and consume energy. This evolved into a desire to understand the details of how proteins, especially membrane proteins function. I worked with Drs. Howard Young and Larry Fliegel in the Department of Biochemistry at the UofA during my PhD to understand the structure and function of eukaryotic ion transporters. In Sweden I worked first with Prof. Gunnar von Heijne to understand how proteins are synthesized and folded into their final 3D structures in living cells and then went on to work on dissecting the biophysical and functional details of large bioenergetic membrane protein complexes with Prof. Ville Kaila. In my spare time I developed my independent interests in investigating a new and exciting group of miniproteins (<100 amino acids long) and particularly those found in the membrane.

Teaching

Lab coordinator and Lecturer, Protein Structure and Function I (Masters’ Level)
Developed from scratch a new lab component for a redeveloped course (protein purification, CD, and ITC)

Lecturer, Experimental Chemical Methods (Bachelor’s Level)
Introduction to protein structure determination and biological, medical and industrial applications

Lecturer, Structural Biochemistry (Masters’ Level)
Macromolecular Structure and Function, and Protein Folding

Featured Publications

Dissected antiporter modules establish minimal proton-conduction elements of the respiratory complex I

NATURE COMMUNICATIONS. 2024 January; 10.1038/S41467-024-53194-5

Investigating the proton translocation mechanism of Complex I from the bottom-up

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2024 January; 10.1016/J.BBABIO.2024.149209

Cotranslational folding cooperativity of contiguous domains of α-spectrin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020 January; 10.1073/PNAS.1909683117

Cotranslational folding of alkaline phosphatase in the periplasm of <i>Escherichia coli</i>

PROTEIN SCIENCE. 2020 January; 10.1002/PRO.3927

Force-Profile Analysis of the Cotranslational Folding of HemK and Filamin Domains: Comparison of Biochemical and Biophysical Folding Assays

JOURNAL OF MOLECULAR BIOLOGY. 2019 January; 10.1016/J.JMB.2019.01.043

Decreased capacity for sodium export out of Arabidopsis chloroplasts impairs salt tolerance, photosynthesis and plant performance

PLANT JOURNAL. 2014 January; 10.1111/TPJ.12501

Membrane transport piece by piece: Production of transmembrane peptides for structural and functional studies

Current Protocols in Protein Science. 2014 January; 10.1002/0471140864.ps2908s75

Small membrane proteins - elucidating the function of the needle in the haystack

BIOLOGICAL CHEMISTRY. 2014 January; 10.1515/HSZ-2014-0213

View additional publications