Glen Jickling

Associate Professor, Faculty of Medicine & Dentistry - Medicine Dept

Contact

Associate Professor, Faculty of Medicine & Dentistry - Medicine Dept
Email
glenj@ualberta.ca
Phone
(780) 248-1095
Address
4-065 Katz Group Centre For Research
11315 - 87 Ave NW
Edmonton AB
T6G 2H5

Overview

Area of Study / Keywords

Transcriptomics Stroke microRNA Immune Response Thrombin generation Vascular cognitive impairment


About

Dr. Jickling’s research focuses on the role of the immune system in cerebrovascular disease including patterns of gene expression and epigenetic regulation. He has described RNA markers in blood as a method to distinguish stroke subtypes and predict cause in strokes of unclear etiology. Dr. Jickling is on the editorial boards of several journals.

Academic Appointments:

2013-2016    Assistant Professor, Department of Neurology, University of California Davis

2014-2016    Director Stroke Program, Department of Neurology, University of California Davis

2016-2020    Assistant Professor, Division of Neurology, University of Alberta, Edmonton, Canada

2022-P          Associate Professor, Division of Neurology, University of Alberta, Edmonton, Canada

Hospital Appointments:

2016-P       University of Alberta Hospital, Edmonton, Alberta

Courses

MED 604 - Translational Research Training Program, Module II

The course aim is to understand the principles in the conduct of early-phase versus large clinical trials and the requirements for successful translation of preclinical research: traditional and novel trial designs, endpoints, statistical challenges, regulatory and funding challenges, structure of translational teams and knowledge translation will be discussed. The syllabus includes a mix of short lectures, debate sessions, one-on-one and group discussions, along with student presentations on topical research oriented questions. This course will support graduate students to be effective translators of discovery and knowledge. Prerequisite: Mandatory for graduate students enrolled in MSc in Medicine -Translational Medicine; consent of Department.


MED 606 - Translational Research Training Program, Module III

The course aim is to recognize the role of biomarkers in clinical research, including early phase trials and clinical care. Principles for the discovery of novel biomarkers at the preclinical and clinical level will be discussed. The syllabus includes a mix of short lectures, debate sessions, one-on-one and group discussions, along with student presentations on topical research oriented questions. This course is designed to align graduate students with the current trends in modern medical training and be effective translators of discovery and knowledge. Prerequisite: consent of Department.


MED 608 - Translational Research Training Program, Module IV

The course aim is to discuss the principles of candidate drug targets in disease and drug design The importance of drug target validation at the cellular level, preclinical level and in clinical studies will be discussed. The syllabus includes a mix of short lectures, debate sessions, one-on-one and group discussions, along with student presentations on topical research oriented questions. This course is designed to align graduate students with the current trends in modern medical training and be effective translators of discovery and knowledge. Prerequisite: consent of Department.


Browse more courses taught by Glen Jickling

Featured Publications

Kamtchum-Tatuene J., Saba L., Heldner M.R., Poorthuis M.H.F., De Borst G.J., Rundek T., Kakkos S.K., Chaturvedi S., Topakian R., Polak J.F., Jickling G.C.

CIRCULATION RESEARCH. 2022 July; 131 (2):E22-E33 10.1161/CIRCRESAHA.122.320877


Sarina Falcione, Danielle Munsterman, Twinkle Joy, Joseph Kamtchum-Tatuene, Gina Sykes, Glen Jickling

NEUROLOGY. 2022 July; 10.1212/WNL.0000000000200909


Menon B.K., Buck B.H., Singh N., Deschaintre Y., Almekhlafi M.A., Coutts S.B., Thirunavukkarasu S., Khosravani H., Appireddy R., Moreau F., Gubitz G., Tkach A., Catanese L., Dowlatshahi D., Medvedev G., Mandzia J., Pikula A., Shankar J., Williams H., Field T.S., Manosalva A., Siddiqui M., Zafar A., Imoukhuede O., Hunter G., Demchuk A.M., Mishra S., Gioia L.C., Jalini S., Cayer C., Phillips S., Elamin E., Shoamanesh A., Subramaniam S., Kate M., Jacquin G., Camden M.C., Benali F., Alhabli I., Bala F., Horn M., Stotts G., Hill M.D., Gladstone D.J., Poppe A., Sehgal A., Zhang Q., Lethebe B.C., Doram C., Ademola A., Shamy M., Kenney C., Sajobi T.T., Swartz R.H., Srivastava A., Aljammaz A.M., Akindotun A.F., Jin A.Y., Fraser A., Khaw A.V., Lemnaru A., Southwell A., Ramji A., Alvarado-Bolaños A., Mouminah A., Lahlouh A.B., Yu A.Y., Alrohimi A., Lavoie A., Rogge A., Micieli A., Nguyen A.L., Callaghan-Brown A., Florendo-Cumbermack A., Wadhwa A., Beaudoin A.M., Cayley A., Liddy A.M., Trivedi A., Katsanos A.H., Shuaib A., Butt A.J., Bereznyakova O., Beauchamp B., Mahlitz B., Graham B.R., Dewar B., Durafourt B.A., Holtby C., Jackson-Tarlton C.S., Bockus C., Stephenson C., Galloway C., Odier C., Deacon C., Zerna C., Vekhande C.C., Bocti C., Stapf C., Hawkes C., Stables C.A., Bogiatzi C., Rodriguez C., Candale-Radu C., Murphy C., Casserly C.S., Fok D., Boasquevisque D.d.S., Wile D., Volders D., Sahlas D.J., Shand E., Cora E.A., Battista E.D., Stewart E., Junk E., Harrison E.L., Frenette E., Teleg E., Abdellah E., Ghrooda E., Akthar F., Evoy F., Klein G.M., Maclean G., Jickling G.C., Hawthorne G., Boyd G., Walker G., Saposnik G., Lau H.L., Badr H.E., Toma H., Kalashyan H., Marion-Moffet H., Grant I., Fatakdawala I., Beaulieu-Boire I., Williams J., Brar J., Rivest J., Wang J.Z., Dawe J., Stang J., Day J., Miller J., Gorman J., Hopyan J.J., Lee J., Kromm J., Foster K., Ratnayake K., Perera K.S., Murray K.V., Ryckborst K., Lin K., Sage K., Sivakuma K., MacDonald K.A., Ng K.K., Merchant K., Khan K., Ghavami K., Johnston K., Mai L.M., White L., Barratt L., Longpre L., Crellin L., Peeling L., Piquette L., Lomax L.B., Sadeghi M., Kamra M., Lavoie-April M., Moores M., Bullrich M.B., McClelland M., Salluzzi M., Wilcox M., Boulos M.I., Marko M., Boyko M., Lantagne-Hurtubise M., AlHamid M.A., Shawawrah M., Kelly M.E., Thorne M.W.D., Bussiere M., Dominc Tse M.Y., Benguzzi M., Sharma M., Horton M., Newcommon N., Simon N.S., Parks N.E., Sultan N., Markovic N., Daneault N., Ishaque N., Fairall P., Kostyrko P.B., Stys P.K., Teal P., Couillard P., King-Azote P., Collier Q., Epp R., Nair R., Joundi R.A., Jassal R., Schneider R., Hosseini R., Bouchard R., Whelan R., Cooley S.R., Sujanthan S., Mansoor S., Yip S., Wasyliw S., Taylor S.W., Friedman S., Mann S., Maley S.W., Chiasson S., Hu S.X., Althubait S., Himed S., Chen S., Bal S.S., Page S.A., Beck S.D., Woodroffe S., Reiter S.D., Gaal S.v., Peters S.R., Darvesh S., Save S., Alcock S., Piercey S., Adam S., Gosselin S., Fitzpatrick T., Perron T.L., Stewart T., Benstead T.J., Naidoo V., Wahab W.A., Oczkowski W., Kingston W., Leduc W., To W.T.H., Yu Y.J., Liu Z.A., Aljundi Z.E.

LANCET. 2022 July; 400 (10347):161-169 10.1016/S0140-6736(22)01054-6


Alrohimi A., Jickling G., Buck B., Butcher K.S.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2022 June; 10.1017/cjn.2022.268


Falcione S.R., Jickling G.C.

STROKE. 2022 April; 53 (4):1245-1246 10.1161/STROKEAHA.121.037525


Beaudin A.E., McCreary C.R., Mazerolle E.L., Gee M., Sharma B., Subotic A., Zwiers A.M., Cox E., Nelles K., Charlton A., Frayne R., Ismail Z., Beaulieu C., Jickling G.C., Camicioli R.M., Pike G.B., Smith E.E.

NEUROLOGY. 2022 April; 98 (17):E1716-E1728 10.1212/WNL.0000000000200136


Nomani A.Z., Rempel J.L., Khan K.A., Shuaib A., Jickling G.C.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2022 March; 10.1017/cjn.2022.9


Kamtchum-Tatuene J., Jickling G.C.

LANCET. 2022 March; 399 (10330):1114-1115 10.1016/S0140-6736(21)02498-3


Jickling GC, Ander BP, Zhan X, Stamova B, Hull H, DeCarli C, Sharp FR

BRAIN. 2022 March; 10.1093/brain/awac107


Knepp B., Ander B.P., Jickling G.C., Hull H., Yee A.H., Ng K., Rodriguez F., Carmona-Mora P., Amini H., Zhan X., Hakoupian M., Alomar N., Sharp F.R., Stamova B.

Brain Hemorrhages. 2022 January; 10.1016/j.hest.2022.04.003


Purdy K., Long R., Jickling G.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2022 January; 106 (3):874-876 10.4269/ajtmh.21-0999


Hakoupian M., Ferino E., Jickling G.C., Amini H., Stamova B., Ander B.P., Alomar N., Sharp F.R., Zhan X.

Scientific Reports. 2021 December; 11 (1) 10.1038/s41598-021-86083-8


Abbasi-Habashi S., Jickling G.C., Winship I.R.

Frontiers in Neurology. 2021 December; 12 10.3389/fneur.2021.746486


Kate M.P., Jeerakathil T., Buck B.H., Khan K., Nomani A.Z., Butt A., Thirunavukkarasu S., Nowacki T., Kalashyan H., Lloret-Villas M.I., D’Souza A., Mishra S., McCombe J., Butcher K., Jickling G., Saqqur M., Shuaib A.

Scientific Reports. 2021 December; 11 (1) 10.1038/s41598-021-84441-0


Nomani A.Z., Tatuene J.K., Rempel J.L., Jeerakathil T., Winship I.R., Khan K.A., Buck B.H., Shuaib A., Jickling G.C.

NEUROLOGY. 2021 November; 97 (21):E2079-E2087 10.1212/WNL.0000000000012855


Durocher M., Knepp B., Yee A., Jickling G., Rodriguez F., Ng K., Zhan X., Hamade F., Ferino E., Amini H., Carmona-Mora P., Hull H., Ander B.P., Sharp F.R., Stamova B.

Translational Stroke Research. 2021 October; 12 (5):754-777 10.1007/s12975-020-00869-y


Kamtchum-Tatuene J., Nomani A.Z., Falcione S., Munsterman D., Sykes G., Joy T., Spronk E., Vargas M.I., Jickling G.C.

Frontiers in Neurology. 2021 September; 12 10.3389/fneur.2021.719329


Butt A., Kamtchum-Tatuene J., Khan K., Shuaib A., Jickling G.C., Miyasaki J.M., Smith E.E., Camicioli R.

Journal of Neurological Sciences-Turkish. 2021 July; 426 10.1016/j.jns.2021.117481


Kung T.F.C., Wilkinson C.M., Dirks C.A., Jickling G.C., Colbourne F.

PLoS ONE. 2021 June; 16 (6 June) 10.1371/journal.pone.0252584


Carmona-Mora P., Ander B.P., Jickling G.C., Dykstra-Aiello C., Zhan X., Ferino E., Hamade F., Amini H., Hull H., Sharp F.R., Stamova B.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021 June; 41 (6):1398-1416 10.1177/0271678X20953912


Buck B.H., Hill M.D., Quinn F.R., Butcher K.S., Menon B.K., Gulamhusein S., Siddiqui M., Coutts S.B., Jeerakathil T., Smith E.E., Khan K., Barber P.A., Jickling G., Reyes L., Save S., Fairall P., Piquette L., Kamal N., Chew D.S., Demchuk A.M., Shuaib A., Exner D.V.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2021 June; 325 (21):2160-2168 10.1001/jama.2021.6128


Spronk E., Sykes G., Falcione S., Munsterman D., Joy T., Kamtchum-Tatuene J., Jickling G.C.

Frontiers in Neurology. 2021 May; 12 10.3389/fneur.2021.661955


Butt A., Kamtchum-Tatuene J., Khan K., Shuaib A., Jickling G.C., Miyasaki J.M., Smith E.E., Camicioli R.

Journal of the Neurological Sciences. 2021 May; 426 10.1016/j.jns.2021.117481


Jickling G.C., Wartenberg K.E.

NEUROLOGY. 2021 April; 96 (15):689-690 10.1212/WNL.0000000000011738


Kate M.P., Jeerakathil T., Buck B.H., Khan K., Nomani A.Z., Butt A., Thirunavukkarasu S., Nowacki T., Kalashyan H., Lloret-Villas M.I., D’Souza A., Mishra S., McCombe J., Butcher K., Jickling G., Saqqur M., Shuaib A.

Scientific Reports. 2021 March; 11 (1) 10.1038/s41598-021-84441-0


Alrohimi A., Jickling G., Jeerakathil T., Shuaib A., Khan K., Kate M., Hill M.D., Buck B., Butcher K.

Frontiers in Neurology. 2021 March; 12 10.3389/fneur.2021.645822


Zhang K., Kamtchum-Tatuene J., Li M., Jickling G.C.

Stroke and Vascular Neurology. 2021 March; 6 (1):128-132 10.1136/svn-2020-000440


Jickling G.C., Wartenberg K.E.

Neurology. 2021 March; 96 (15):689-690 10.1212/WNL.0000000000011738


Hakoupian M., Ferino E., Jickling G.C., Amini H., Stamova B., Ander B.P., Alomar N., Sharp F.R., Zhan X.

Scientific Reports. 2021 March; 11 (1) 10.1038/s41598-021-86083-8


Sykes G.P., Kamtchum-Tatuene J., Falcione S., Zehnder S., Munsterman D., Stamova B., Ander B.P., Sharp F.R., Jickling G.

STROKE. 2021 March; 52 (4):1355-1361 10.1161/STROKEAHA.120.032040


Wilkinson C.M., Kung T.F.C., Jickling G.C., Colbourne F.

Brain Hemorrhages. 2021 March; 2 (1):34-48 10.1016/j.hest.2020.10.002


Roever L., Jickling G.C.

Neurology. 2021 February; 96 (7):301-302 10.1212/WNL.0000000000011491


Wilkinson CM, Kung TFC, Jickling GC, Colbourne

Science Direct. 2021 February; 2 (1):34-48 10.1016/j.hest.2020.10.002


Roever L., Jickling G.C.

Neurology. 2021 February; 96 (7):301-302 10.1212/WNL.0000000000011491


Alrohimi A., Buck B., Jickling G., Shuaib A., Thirunavukkarasu S., Butcher K.S.

Journal of Neurology. 2021 January; 268 (5):1837-1846 10.1007/s00415-020-10335-2


Kamtchum-Tatuene J., Jickling G.C.

Stroke. 2021 January; 52 (2):e64-e65 10.1161/STROKEAHA.120.032698


Kamtchum-Tatuene J., Noubiap J.J., Wilman A.H., Saqqur M., Shuaib A., Jickling G.C.

JAMA Neurology. 2020 December; 77 (12):1524-1535 10.1001/jamaneurol.2020.2658


Durocher M., Knepp B., Yee A., Jickling G., Rodriguez F., Ng K., Zhan X., Hamade F., Ferino E., Amini H., Carmona-Mora P., Hull H., Ander B.P., Sharp F.R., Stamova B.

Translational Stroke Research. 2020 November; 10.1007/s12975-020-00869-y


Dykstra-Aiello C., Sharp F.R., Jickling G.C., Hull H., Hamade F., Shroff N., Durocher M., Cheng X., Zhan X., Liu D.Z., Ander B.P., Stamova B.S.

Frontiers in Neurology. 2020 October; 11 10.3389/fneur.2020.584695


Amini H., Shroff N., Stamova B., Ferino E., Carmona-Mora P., Zhan X., Sitorus P.P., Hull H., Jickling G.C., Sharp F.R., Ander B.P.

Annals of Clinical and Translational Neurology. 2020 September; 7 (9):1648-1660 10.1002/acn3.51154