Glen Jickling
Contact
Associate Professor, Faculty of Medicine & Dentistry - Medicine Dept
- glenj@ualberta.ca
- Phone
- (780) 248-1095
- Address
-
4-065 Katz Group Centre For Research
11315 - 87 Ave NWEdmonton ABT6G 2H5
Overview
Area of Study / Keywords
Transcriptomics Stroke microRNA Immune Response Thrombin generation Vascular cognitive impairment
About
Dr. Jickling’s research focuses on the role of the immune system in cerebrovascular disease including patterns of gene expression and epigenetic regulation. He has described RNA markers in blood as a method to distinguish stroke subtypes and predict cause in strokes of unclear etiology. Dr. Jickling is on the editorial boards of several journals.
Academic Appointments:2013-2016 Assistant Professor, Department of Neurology, University of California Davis
2014-2016 Director Stroke Program, Department of Neurology, University of California Davis
2016-2020 Assistant Professor, Division of Neurology, University of Alberta, Edmonton, Canada
2022-P Associate Professor, Division of Neurology, University of Alberta, Edmonton, Canada
Hospital Appointments:
2016-P University of Alberta Hospital, Edmonton, Alberta
Courses
MED 606 - Translational Research Training Program, Module III
The course aim is to recognize the role of biomarkers in clinical research, including early phase trials and clinical care. Principles for the discovery of novel biomarkers at the preclinical and clinical level will be discussed. The syllabus includes a mix of short lectures, debate sessions, one-on-one and group discussions, along with student presentations on topical research oriented questions. This course is designed to align graduate students with the current trends in modern medical training and be effective translators of discovery and knowledge. Prerequisite: consent of Department.
MED 608 - Translational Research Training Program, Module IV
The course aim is to discuss the principles of candidate drug targets in disease and drug design The importance of drug target validation at the cellular level, preclinical level and in clinical studies will be discussed. The syllabus includes a mix of short lectures, debate sessions, one-on-one and group discussions, along with student presentations on topical research oriented questions. This course is designed to align graduate students with the current trends in modern medical training and be effective translators of discovery and knowledge. Prerequisite: consent of Department.
Featured Publications
Kamtchum-Tatuene J., Saba L., Heldner M.R., Poorthuis M.H.F., De Borst G.J., Rundek T., Kakkos S.K., Chaturvedi S., Topakian R., Polak J.F., Jickling G.C.
CIRCULATION RESEARCH. 2022 July; 131 (2):E22-E33 10.1161/CIRCRESAHA.122.320877
Sarina Falcione, Danielle Munsterman, Twinkle Joy, Joseph Kamtchum-Tatuene, Gina Sykes, Glen Jickling
NEUROLOGY. 2022 July; 10.1212/WNL.0000000000200909
Menon B.K., Buck B.H., Singh N., Deschaintre Y., Almekhlafi M.A., Coutts S.B., Thirunavukkarasu S., Khosravani H., Appireddy R., Moreau F., Gubitz G., Tkach A., Catanese L., Dowlatshahi D., Medvedev G., Mandzia J., Pikula A., Shankar J., Williams H., Field T.S., Manosalva A., Siddiqui M., Zafar A., Imoukhuede O., Hunter G., Demchuk A.M., Mishra S., Gioia L.C., Jalini S., Cayer C., Phillips S., Elamin E., Shoamanesh A., Subramaniam S., Kate M., Jacquin G., Camden M.C., Benali F., Alhabli I., Bala F., Horn M., Stotts G., Hill M.D., Gladstone D.J., Poppe A., Sehgal A., Zhang Q., Lethebe B.C., Doram C., Ademola A., Shamy M., Kenney C., Sajobi T.T., Swartz R.H., Srivastava A., Aljammaz A.M., Akindotun A.F., Jin A.Y., Fraser A., Khaw A.V., Lemnaru A., Southwell A., Ramji A., Alvarado-Bolaños A., Mouminah A., Lahlouh A.B., Yu A.Y., Alrohimi A., Lavoie A., Rogge A., Micieli A., Nguyen A.L., Callaghan-Brown A., Florendo-Cumbermack A., Wadhwa A., Beaudoin A.M., Cayley A., Liddy A.M., Trivedi A., Katsanos A.H., Shuaib A., Butt A.J., Bereznyakova O., Beauchamp B., Mahlitz B., Graham B.R., Dewar B., Durafourt B.A., Holtby C., Jackson-Tarlton C.S., Bockus C., Stephenson C., Galloway C., Odier C., Deacon C., Zerna C., Vekhande C.C., Bocti C., Stapf C., Hawkes C., Stables C.A., Bogiatzi C., Rodriguez C., Candale-Radu C., Murphy C., Casserly C.S., Fok D., Boasquevisque D.d.S., Wile D., Volders D., Sahlas D.J., Shand E., Cora E.A., Battista E.D., Stewart E., Junk E., Harrison E.L., Frenette E., Teleg E., Abdellah E., Ghrooda E., Akthar F., Evoy F., Klein G.M., Maclean G., Jickling G.C., Hawthorne G., Boyd G., Walker G., Saposnik G., Lau H.L., Badr H.E., Toma H., Kalashyan H., Marion-Moffet H., Grant I., Fatakdawala I., Beaulieu-Boire I., Williams J., Brar J., Rivest J., Wang J.Z., Dawe J., Stang J., Day J., Miller J., Gorman J., Hopyan J.J., Lee J., Kromm J., Foster K., Ratnayake K., Perera K.S., Murray K.V., Ryckborst K., Lin K., Sage K., Sivakuma K., MacDonald K.A., Ng K.K., Merchant K., Khan K., Ghavami K., Johnston K., Mai L.M., White L., Barratt L., Longpre L., Crellin L., Peeling L., Piquette L., Lomax L.B., Sadeghi M., Kamra M., Lavoie-April M., Moores M., Bullrich M.B., McClelland M., Salluzzi M., Wilcox M., Boulos M.I., Marko M., Boyko M., Lantagne-Hurtubise M., AlHamid M.A., Shawawrah M., Kelly M.E., Thorne M.W.D., Bussiere M., Dominc Tse M.Y., Benguzzi M., Sharma M., Horton M., Newcommon N., Simon N.S., Parks N.E., Sultan N., Markovic N., Daneault N., Ishaque N., Fairall P., Kostyrko P.B., Stys P.K., Teal P., Couillard P., King-Azote P., Collier Q., Epp R., Nair R., Joundi R.A., Jassal R., Schneider R., Hosseini R., Bouchard R., Whelan R., Cooley S.R., Sujanthan S., Mansoor S., Yip S., Wasyliw S., Taylor S.W., Friedman S., Mann S., Maley S.W., Chiasson S., Hu S.X., Althubait S., Himed S., Chen S., Bal S.S., Page S.A., Beck S.D., Woodroffe S., Reiter S.D., Gaal S.v., Peters S.R., Darvesh S., Save S., Alcock S., Piercey S., Adam S., Gosselin S., Fitzpatrick T., Perron T.L., Stewart T., Benstead T.J., Naidoo V., Wahab W.A., Oczkowski W., Kingston W., Leduc W., To W.T.H., Yu Y.J., Liu Z.A., Aljundi Z.E.
LANCET. 2022 July; 400 (10347):161-169 10.1016/S0140-6736(22)01054-6
Alrohimi A., Jickling G., Buck B., Butcher K.S.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2022 June; 10.1017/cjn.2022.268
Falcione S.R., Jickling G.C.
STROKE. 2022 April; 53 (4):1245-1246 10.1161/STROKEAHA.121.037525
Beaudin A.E., McCreary C.R., Mazerolle E.L., Gee M., Sharma B., Subotic A., Zwiers A.M., Cox E., Nelles K., Charlton A., Frayne R., Ismail Z., Beaulieu C., Jickling G.C., Camicioli R.M., Pike G.B., Smith E.E.
NEUROLOGY. 2022 April; 98 (17):E1716-E1728 10.1212/WNL.0000000000200136
Nomani A.Z., Rempel J.L., Khan K.A., Shuaib A., Jickling G.C.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2022 March; 10.1017/cjn.2022.9
Kamtchum-Tatuene J., Jickling G.C.
LANCET. 2022 March; 399 (10330):1114-1115 10.1016/S0140-6736(21)02498-3
Jickling GC, Ander BP, Zhan X, Stamova B, Hull H, DeCarli C, Sharp FR
BRAIN. 2022 March; 10.1093/brain/awac107
Knepp B., Ander B.P., Jickling G.C., Hull H., Yee A.H., Ng K., Rodriguez F., Carmona-Mora P., Amini H., Zhan X., Hakoupian M., Alomar N., Sharp F.R., Stamova B.
Brain Hemorrhages. 2022 January; 10.1016/j.hest.2022.04.003
Purdy K., Long R., Jickling G.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2022 January; 106 (3):874-876 10.4269/ajtmh.21-0999
Hakoupian M., Ferino E., Jickling G.C., Amini H., Stamova B., Ander B.P., Alomar N., Sharp F.R., Zhan X.
Scientific Reports. 2021 December; 11 (1) 10.1038/s41598-021-86083-8
Abbasi-Habashi S., Jickling G.C., Winship I.R.
Frontiers in Neurology. 2021 December; 12 10.3389/fneur.2021.746486
Kate M.P., Jeerakathil T., Buck B.H., Khan K., Nomani A.Z., Butt A., Thirunavukkarasu S., Nowacki T., Kalashyan H., Lloret-Villas M.I., D’Souza A., Mishra S., McCombe J., Butcher K., Jickling G., Saqqur M., Shuaib A.
Scientific Reports. 2021 December; 11 (1) 10.1038/s41598-021-84441-0
Nomani A.Z., Tatuene J.K., Rempel J.L., Jeerakathil T., Winship I.R., Khan K.A., Buck B.H., Shuaib A., Jickling G.C.
NEUROLOGY. 2021 November; 97 (21):E2079-E2087 10.1212/WNL.0000000000012855
Durocher M., Knepp B., Yee A., Jickling G., Rodriguez F., Ng K., Zhan X., Hamade F., Ferino E., Amini H., Carmona-Mora P., Hull H., Ander B.P., Sharp F.R., Stamova B.
Translational Stroke Research. 2021 October; 12 (5):754-777 10.1007/s12975-020-00869-y
Kamtchum-Tatuene J., Nomani A.Z., Falcione S., Munsterman D., Sykes G., Joy T., Spronk E., Vargas M.I., Jickling G.C.
Frontiers in Neurology. 2021 September; 12 10.3389/fneur.2021.719329
Butt A., Kamtchum-Tatuene J., Khan K., Shuaib A., Jickling G.C., Miyasaki J.M., Smith E.E., Camicioli R.
Journal of Neurological Sciences-Turkish. 2021 July; 426 10.1016/j.jns.2021.117481
Kung T.F.C., Wilkinson C.M., Dirks C.A., Jickling G.C., Colbourne F.
PLoS ONE. 2021 June; 16 (6 June) 10.1371/journal.pone.0252584
Carmona-Mora P., Ander B.P., Jickling G.C., Dykstra-Aiello C., Zhan X., Ferino E., Hamade F., Amini H., Hull H., Sharp F.R., Stamova B.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021 June; 41 (6):1398-1416 10.1177/0271678X20953912
Buck B.H., Hill M.D., Quinn F.R., Butcher K.S., Menon B.K., Gulamhusein S., Siddiqui M., Coutts S.B., Jeerakathil T., Smith E.E., Khan K., Barber P.A., Jickling G., Reyes L., Save S., Fairall P., Piquette L., Kamal N., Chew D.S., Demchuk A.M., Shuaib A., Exner D.V.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2021 June; 325 (21):2160-2168 10.1001/jama.2021.6128
Spronk E., Sykes G., Falcione S., Munsterman D., Joy T., Kamtchum-Tatuene J., Jickling G.C.
Frontiers in Neurology. 2021 May; 12 10.3389/fneur.2021.661955
Butt A., Kamtchum-Tatuene J., Khan K., Shuaib A., Jickling G.C., Miyasaki J.M., Smith E.E., Camicioli R.
Journal of the Neurological Sciences. 2021 May; 426 10.1016/j.jns.2021.117481
Jickling G.C., Wartenberg K.E.
NEUROLOGY. 2021 April; 96 (15):689-690 10.1212/WNL.0000000000011738
Kate M.P., Jeerakathil T., Buck B.H., Khan K., Nomani A.Z., Butt A., Thirunavukkarasu S., Nowacki T., Kalashyan H., Lloret-Villas M.I., D’Souza A., Mishra S., McCombe J., Butcher K., Jickling G., Saqqur M., Shuaib A.
Scientific Reports. 2021 March; 11 (1) 10.1038/s41598-021-84441-0
Alrohimi A., Jickling G., Jeerakathil T., Shuaib A., Khan K., Kate M., Hill M.D., Buck B., Butcher K.
Frontiers in Neurology. 2021 March; 12 10.3389/fneur.2021.645822
Zhang K., Kamtchum-Tatuene J., Li M., Jickling G.C.
Stroke and Vascular Neurology. 2021 March; 6 (1):128-132 10.1136/svn-2020-000440
Jickling G.C., Wartenberg K.E.
Neurology. 2021 March; 96 (15):689-690 10.1212/WNL.0000000000011738
Hakoupian M., Ferino E., Jickling G.C., Amini H., Stamova B., Ander B.P., Alomar N., Sharp F.R., Zhan X.
Scientific Reports. 2021 March; 11 (1) 10.1038/s41598-021-86083-8
Sykes G.P., Kamtchum-Tatuene J., Falcione S., Zehnder S., Munsterman D., Stamova B., Ander B.P., Sharp F.R., Jickling G.
STROKE. 2021 March; 52 (4):1355-1361 10.1161/STROKEAHA.120.032040
Wilkinson C.M., Kung T.F.C., Jickling G.C., Colbourne F.
Brain Hemorrhages. 2021 March; 2 (1):34-48 10.1016/j.hest.2020.10.002
Roever L., Jickling G.C.
Neurology. 2021 February; 96 (7):301-302 10.1212/WNL.0000000000011491
Wilkinson CM, Kung TFC, Jickling GC, Colbourne
Science Direct. 2021 February; 2 (1):34-48 10.1016/j.hest.2020.10.002
Roever L., Jickling G.C.
Neurology. 2021 February; 96 (7):301-302 10.1212/WNL.0000000000011491
Alrohimi A., Buck B., Jickling G., Shuaib A., Thirunavukkarasu S., Butcher K.S.
Journal of Neurology. 2021 January; 268 (5):1837-1846 10.1007/s00415-020-10335-2
Kamtchum-Tatuene J., Jickling G.C.
Stroke. 2021 January; 52 (2):e64-e65 10.1161/STROKEAHA.120.032698
Kamtchum-Tatuene J., Noubiap J.J., Wilman A.H., Saqqur M., Shuaib A., Jickling G.C.
JAMA Neurology. 2020 December; 77 (12):1524-1535 10.1001/jamaneurol.2020.2658
Durocher M., Knepp B., Yee A., Jickling G., Rodriguez F., Ng K., Zhan X., Hamade F., Ferino E., Amini H., Carmona-Mora P., Hull H., Ander B.P., Sharp F.R., Stamova B.
Translational Stroke Research. 2020 November; 10.1007/s12975-020-00869-y
Dykstra-Aiello C., Sharp F.R., Jickling G.C., Hull H., Hamade F., Shroff N., Durocher M., Cheng X., Zhan X., Liu D.Z., Ander B.P., Stamova B.S.
Frontiers in Neurology. 2020 October; 11 10.3389/fneur.2020.584695
Amini H., Shroff N., Stamova B., Ferino E., Carmona-Mora P., Zhan X., Sitorus P.P., Hull H., Jickling G.C., Sharp F.R., Ander B.P.
Annals of Clinical and Translational Neurology. 2020 September; 7 (9):1648-1660 10.1002/acn3.51154