Ian Winship
Contact
Professor, Faculty of Medicine & Dentistry - Psychiatry Dept
- iwinship@ualberta.ca
- Phone
- (780) 492-8658
- Address
-
12-131 Clinical Sciences Building
11304 - 83 Ave NWEdmonton ABT6G 2G3
Overview
Area of Study / Keywords
two photon microscopy functional neuroanatomy stroke; spinal cord; plasticity; recovery extracellular matrix; rehabilitation schizophrenia; extracellular matrix; animal models chondroitin sulfate proteoglycans maternal immune activation collateral blood flow stroke collateral therapeutics blood flow imaging animal models
About
Dr. Winship is an Associate Professor and a former Alberta Innovates Health Solutions Scholar (2010-2017) in the Department of Psychiatry at the University of Alberta. As Director of the Neurochemical Research Unit (NRU), he works with a diverse group of scientists that are investigating the fundamental neurobiology of the CNS and performing clinical translational research to develop new therapies for psychiatric and neurological disorders.
Research
Research in the Winship lab combines advanced imaging and behavioural neuroscience to better understand how the integrated CNS functions and identify key pathophysiological or adaptive processes in brain disease. These insights are used to develop new therapies for disorders including stroke, multiple sclerosis, and schizophrenia. Key areas of current research include the pathophysiology of schizophrenia (CIHR, in collaboration with John Howland, USask), collateral blood flow and collateral therapeutics during stroke (HSFC; QNRF, in collaboration with Ashfaq Shuaib), and plasticity after stroke as a target for therapy (CIHR, in collaboration with Karim Fouad).Teaching
PMCOL 412 (stroke, epilepsy, and pharmacotherapy)
PSYCH 511 (models of psychiatric disorders)
Featured Publications
Abbasi-Hibashi S, Bui A, Ma Y, Jickling G, Winship IR (2022) Imaging cerebrovascular hemodynamics in mouse models of ischemic stroke: illuminating the role of neutrophils in collateral and microcirculatory failure.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Bandet MV Trinh F, Aqueel R, Mix G, Bui A, Winship IR (2022) Longitudinal calcium imaging of the somatosensory cortex in awake mobile mice demonstrates a disruption in neural activity, network connectivity, and in the function of neural assemblies after stroke.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Doosti MH, Mix G, Montoya Sanchez J, Bandet MV, Winship IR (2022) Pathophysiology of retrosplenial cortex in acute and chronic pharmacological models of cognitive impairment in schizophrenia.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Gupta S, Churchward MA, Todd KG, Winship IR (2022) Pleiotrophin as a modulator of neurite outgrowth, neuroinflammation and OPC differentiation in the presence of CSPGs.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Tanase CS, Bertenshaw RM, Kent P, Wiersma AM, Munchrath E, Thraya A, Winship IR (2022) Exploring the impact of endogenous and exogenous pleiotrophin in post-stroke recovery in mice.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Yu Z, Zahacy R, Ma Y, Winship IR, Chan AW (2022) Investigating the intrinsic noisiness of cortical sensory processing.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Zahacy R, Ma Y, Winship IR, Jackson J, Chan AW (2022) Cortical effects of chemogenetic modulation of claustral activity using DREADDs in Thy-1-GCaMP6s mice.
Annual Meeting of the Canadian Association for Neuroscience, Toronto, ON. . 2022 May;
Biorxiv. 2022 April; https://doi.org/10.1101/2022.04.01.486745
Abbasi-Habashi S., Jickling G.C., Winship I.R.
Frontiers in Neurology. 2021 December; 12 10.3389/fneur.2021.746486
Nomani A.Z., Tatuene J.K., Rempel J.L., Jeerakathil T., Winship I.R., Khan K.A., Buck B.H., Shuaib A., Jickling G.C.
NEUROLOGY. 2021 November; 97 (21):E2079-E2087 10.1212/WNL.0000000000012855
Jesudasan S.J.B., Gupta S.J., Churchward M.A., Todd K.G., Winship I.R.
Frontiers in Cellular Neuroscience. 2021 April; 15 10.3389/fncel.2021.634020
Bandet M.V., Dong B., Winship I.R.
PLoS One. 2021 April; 16 (4 April) 10.1371/journal.pone.0236684
Kalisvaart A.C.J., Wilkinson C.M., Gu S., Kung T.F.C., Yager J., Winship I.R., van Landeghem F.K.H., Colbourne F.
Scientific Reports. 2020 December; 10 (1) 10.1038/s41598-020-78880-4
Ma J., Ma Y., Shuaib A., Winship I.R.
Scientific Reports. 2020 December; 10 (1) 10.1038/s41598-020-69122-8