Jean Buteau, PhD
PhD in Biochemistry, University of Montreal
Canadian Institutes of Health Research, New Investigator Award, 2013-2018
Canadian Diabetes Association, Scholar Award, 2008-2013
Quebec Research Funds, Junior Investigator Award, 2008-2012
Keywords: Diabetes, Obesity, Nutritional and hormonal regulation of beta-cell mass and function.
Our research efforts are aimed at identifying novel molecular mechanisms that govern beta-cell differentiation, proliferation, and survival. The overall goal is to harness the therapeutic potential of these newly discovered targets to stimulate the generation of new beta-cells and to expand and protect the functional beta-cells that still reside in the pancreas of patients with diabetes.
This is an advanced course examining the relationship between the role of lifestyle factors in the etiology and pathophysiology, as well as the treatment of type 2 diabetes and cardiovascular disease. Application of recent findings to our understanding of these chronic metabolic diseases will be addressed. Not to be taken if credit received for NUTR 443. Prerequisite: consent of instructor.
This is an advanced course examining the relationship between the role of lifestyle factors in the etiology and pathophysiology, as well as the treatment of type 2 diabetes and cardiovascular disease. Application of recent findings to our understanding of these chronic metabolic diseases will be addressed. Prerequisites: (NUTR 301 or 303) and (NUTR 302 or 304).
An independent research project on topics in nutritional science and supervised by a faculty member. Normally this is a continuation of work begun in NUTR 400. It includes implementation of a research project relevant to dietetic practice, data analysis and presentation of results orally and in writing. Prerequisite: NUTR 400.
Talbot J, Joly E, Prentki M, Buteau J.
Mol Cell Endocrinol. 364 (1-2):65-70
Diabetes Metab.. 34 (Suppl. 2):S.73-S.77
Bastien-Dionne PO, Valenti L, Kon N, Gu W, Buteau J.
Diabetes. 60 (12):3217-3222
Biswas SC, Buteau J, Greene LA.
Neurochem Res.. 33 (9):1845-1851
El-Assaad W, Joly E, Barbeau A, Sladek R, Buteau J, Maestre I, Pepin E, Zhao S, Iglesias J, Roche E, Prentki M.
Endocrinology. 151 (7):3061-3073
Buteau J, Shlien A, Foisy S, Accili D.
J Biol Chem.. 282 (1):287-293
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, Caparros E, Buteau J, Brown K, Perkins SL, Bhagat G, Agarwal AM, Basso G, Castillo M, Nagase S, Cordon-Cardo C, Parsons R, Zúñiga-Pflücker JC, Dominguez M, Ferrando AA.
Nat Med.. 13 (10):1203-1210
Buteau J, Accili D.
Diabetes Obes Metab.. 9 (Suppl 2):140-146
Buteau J, Spatz ML, Accili D.
Diabetes. 55 (5):1190-1196