Jason Plemel, PhD

Associate Professor, Faculty of Medicine & Dentistry - Medicine Dept

Personal Website: https://amsrguofa.ca/

Contact

Associate Professor, Faculty of Medicine & Dentistry - Medicine Dept
Email
jrplemel@ualberta.ca
Address
5-64 (Office) HMRC - MSB/WMC Link
11207 - 87 Ave NW
Edmonton AB
T6G 2S2

Overview

Area of Study / Keywords

Multiple Sclerosis Microglia Myelin oligodendrocyte


About

Assistant Professor:  of Alberta starting                              June 1st 2018-present


Postdoctoral Researcher: University of Calgary                                 January 2013-May 2018

Advisor: Dr. Peter Stys and Dr. V. Wee Yong


Doctorate (Ph.D.), Neuroscience: University of British Columbia      2005-2012

Advisor: Dr. Wolfram Tetzlaff


Awards:

Postdoctoral Fellowship Award: Alberta Innovates: Health Solutions 07/2015- 06/2018


Postdoctoral Fellowship Award: Canadian Institutes of Health Research 07/2014 - 06/2017


Postdoctoral Fellowship Award: Multiple Sclerosis Society of Canada, Joan Oxford award 06/2013 - 06/2014


Postdoctoral Fellowship Award: University of Calgary, T. Chen Fong award 06/2013 - 06/2014


Research

Using innovative techniques and experimental designs, my laboratory aims to explore white matter injury and repair in Multiple Sclerosis. We aim to better understand the mechanisms of cell death and white matter degeneration, as well as the complex immune response following white matter injury. These studies will guide the complementary objective of mitigating inflammatory injury and improving white matter .

Featured Publications

Hammond BP, Panda SP, Kaushik DK, Plemel JR

Advances in neurobiology. 2024 January; 10.1007/978-3-031-55529-9_25


Baaklini CS, Ho MFS, Lange T, Hammond BP, Panda SP, Zirngibl M, Zia S, Himmelsbach K, Rana H, Phillips B, Antoszko D, Ibanga J, Lopez M, Lee KV, Keough MB, Caprariello AV, Kerr BJ, Plemel JR

Cell reports. 2023 December; 10.1016/j.celrep.2023.113574


Zia S, Hammond BP, Martin Zirngibl, Sizov A, Baaklini CS, Panda SP, Ho MFS, Lee KV, Mainali A, Burr MK, Williams S, Caprariello AV, Power C, Simmen T, Kerr BJ, Jason R Plemel

Molecular neurodegeneration. 2022 December; 10.1186/s13024-022-00584-2


Luke M. Healy, Sameera Zia, Jason R. Plemel

Communications Biology. 2022 October; 10.1038/s42003-022-04081-6


Zirngibl M., Assinck P., Sizov A., Caprariello A.V., Plemel J.R.

Molecular Neurodegeneration. 2022 May; 17 (1) 10.1186/s13024-022-00538-8


Zirngibl M, Assinck P, Sizov A, Caprariello AV, Plemel JR

Molecular neurodegeneration. 2022 May; 10.1186/s13024-022-00538-8


Kamma E., Lasisi W., Libner C., Ng H.S., Plemel J.R.

Journal of Neuroinflammation. 2022 February; 19 (1) 10.1186/s12974-022-02408-y


Hammond B.P., Manek R., Kerr B.J., Macauley M.S., Plemel J.R.

Glia. 2021 December; 69 (12):2771-2797 10.1002/glia.24047


Hammond B.P., Manek R., Kerr B.J., Macauley M.S., Plemel J.R.

GLIA. 2021 January; 10.1002/glia.24047


Zia S., Rawji K.S., Michaels N.J., Burr M., Kerr B.J., Healy L.M., Plemel J.R.

Frontiers in Immunology. 2020 November; 11 10.3389/fimmu.2020.588021


Jason R. Plemel, Jo Anne Stratton, Nathan J. Michaels, Khalil S. Rawji, Eric Zhang, Sarthak Sinha, Charbel S. Baaklini, Yifei Dong, Madelene Ho, Kevin Thorburn, Timothy N. Friedman, Sana Jawad, Claudia Silva, Andrew V. Caprariello, Vahid Hoghooghi, Julie Yue, Arzina Jaffer, Kelly Lee, Bradley J. Kerr, Raj Midha, Peter K. Stys, Jeff Biernaskie, V. Wee Yong

Science Advances. 2020 January; 10.1126/sciadv.aay6324


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