Jason Plemel

Assistant Professor, Faculty of Medicine & Dentistry - Medicine Dept


Assistant Professor, Faculty of Medicine & Dentistry - Medicine Dept


Area of Study / Keywords

Multiple Sclerosis Microglia Myelin oligodendrocyte


Assistant Professor: University of Alberta starting                              June 1st 2018-present

Postdoctoral Researcher: University of Calgary                                 January 2013-May 2018

Advisor: Dr. Peter Stys and Dr. V. Wee Yong

Doctorate (Ph.D.), Neuroscience: University of British Columbia      2005-2012

Advisor: Dr. Wolfram Tetzlaff


Postdoctoral Fellowship Award: Alberta Innovates: Health Solutions 07/2015- 06/2018

Postdoctoral Fellowship Award: Canadian Institutes of Health Research 07/2014 - 06/2017

Postdoctoral Fellowship Award: Multiple Sclerosis Society of Canada, Joan Oxford award 06/2013 - 06/2014

Postdoctoral Fellowship Award: University of Calgary, T. Chen Fong award 06/2013 - 06/2014


Using innovative techniques and experimental designs, my laboratory aims to explore white matter injury and repair in Multiple Sclerosis. We aim to better understand the mechanisms of cell death and white matter degeneration, as well as the complex immune response following white matter injury. These studies will guide the complementary objective of mitigating inflammatory injury and improving white matter regeneration.


Featured Publications

Zirngibl M., Assinck P., Sizov A., Caprariello A.V., Plemel J.R.

Molecular Neurodegeneration. 2022 May; 17 (1) 10.1186/s13024-022-00538-8

Kamma E., Lasisi W., Libner C., Ng H.S., Plemel J.R.

Journal of Neuroinflammation. 2022 February; 19 (1) 10.1186/s12974-022-02408-y

Huitema M.J.D., Strijbis E.M.M., Luchicchi A., Bol J.G.J.M., Plemel J.R., Geurts J.J.G., Schenk G.J.

International Journal of Molecular Sciences. 2021 December; 22 (23) 10.3390/ijms222312634

Hammond B.P., Manek R., Kerr B.J., Macauley M.S., Plemel J.R.

Glia. 2021 December; 69 (12):2771-2797 10.1002/glia.24047

Bhattacherjee A., Jung J., Zia S., Ho M., Eskandari-Sedighi G., St. Laurent C.D., McCord K.A., Bains A., Sidhu G., Sarkar S., Plemel J.R., Macauley M.S.

Molecular Neurodegeneration. 2021 March; 16 (1) 10.1186/s13024-021-00443-6

Plemel J.R., Yong V.W.

Trends in Neurosciences. 2021 January; 10.1016/j.tins.2021.06.002

Hammond B.P., Manek R., Kerr B.J., Macauley M.S., Plemel J.R.

GLIA. 2021 January; 10.1002/glia.24047

Zia S., Rawji K.S., Michaels N.J., Burr M., Kerr B.J., Healy L.M., Plemel J.R.

Frontiers in Immunology. 2020 November; 11 10.3389/fimmu.2020.588021

Michaels N.J., Lemmon K., Plemel J.R., Jensen S.K., Mishra M.K., Brown D., Rawji K.S., Koch M., Wee Yong V.

Journal of Neuroscience. 2020 October; 40 (44):8587-8600 10.1523/JNEUROSCI.1098-20.2020