Sanjay Kalra, MD, FRCPC

Professor and Henri M. Toupin Chair in Neurological Sciences, Faculty of Medicine & Dentistry - Medicine Dept Neurology

Personal Website: https://www.alsniru.com/

Contact

Professor and Henri M. Toupin Chair in Neurological Sciences, Faculty of Medicine & Dentistry - Medicine Dept Neurology
Email
kalra@ualberta.ca
Phone
(780) 248-1777

Overview

Area of Study / Keywords

ALS MRI Biomarker Neuroscience Neuroimaging Neurodegeneration


About

Education and Training

  • BSc, University of Toronto
  • MD, University of Toronto
  • FRCPC in Neurology, McGill University
  • Research Fellowship, Montreal Neurological Institute

Academic Appointments

  • Professor, Division of Neurology, Department of Medicine
  • Adjunct Professor, Department of Computing Science
  • Adjunct Professor, Department of Biomedical Engineering

Member

  • Neuroscience and Mental Health Institute (NMHI)
  • Neuroimaging Society in ALS (NiSALS)

Research

Research Areas

  • Amyotrophic Lateral Sclerosis (ALS)
  • Neuroimaging
  • Biomarkers

Research Projects

  • The Canadian ALS Neuroimaging Consortium (CALSNIC) [Director]
  • The Comprehensive Analysis Platform To Understand, Remedy, and Eliminate ALS (CAPTURE) [Director]
  • Multimodal Neuroimaging: Magnetic Resonance Spectroscopy, Diffusion Tensor Imaging, Magnetic Resonance Volumetry, Functional MRI, Texture Analysis

Featured Publications

Christian Marius Lillelund, Sanjay Kalra, Russell Greiner

PLOS One. 2025 November; 10.1371/journal.pone.0336476


Parnianpour P, Benatar M, Briemberg H, Dey A, Dionne A, Dupré N, Evans KC, Frayne R, Genge A, Graham SJ, Korngut L, McLaren DG, Seres P, Welsh RC, Wilman A, Zinman L, Kalra S

Journal of neurology. 2024 January; 10.1007/s00415-024-12190-x


Rafsanjany Kushol, Sanjay Kalra, Yee-Hong Yang

2024 January; 10.1007/978-3-031-66955-2_6


Sadegh Ghaderi, Farzad Fatehi, Sanjay Kalra, Seyed Amir Hossein Batouli

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2023 October; 10.1080/21678421.2023.2236651


Rafsanjany Kushol, Alan H. Wilman, Sanjay Kalra, Yee-Hong Yang

Diagnostics. 2023 September; 10.3390/diagnostics13182947


Tanushka Anand, Abdullah Ishaque, Daniel Ta, Muhammad Umer Khan, Komal Bharti, Andrew Wu, Dennell Krebs, Christian Beaulieu, Peter Seres, Sanjay Kalra

Brain and Behavior. 2023 July; 10.1002/brb3.3102


Daniel Ta, Abdullah H. Ishaque, Adam Elamy, Tanushka Anand, Andrew Wu, Dean T. Eurich, Collin Luk, Yee Hong Yang, Sanjay Kalra

European Journal of Neurology. 2023 May; 10.1111/ene.15686


Avyarthana Dey, Collin Luk, Abdullah Ishaque, Daniel Ta, Ojas Srivastava, Dennell Krebs, Peter Seres, Chris Hanstock, Christian Beaulieu, Lawrence Korngut, Richard Frayne, Lorne Zinman, Simon Graham, Angela Genge, Hannah Briemberg, Sanjay Kalra

Journal of Neurology, Neurosurgery & Psychiatry. 2023 March; 10.1136/jnnp-2022-329993


Mejia A.F., Koppelmans V., Jelsone-Swain L., Kalra S., Welsh R.C.

NEUROIMAGE. 2022 July; 255 10.1016/j.neuroimage.2022.119180


Bharti K., Graham S.J., Benatar M., Briemberg H., Chenji S., Dupré N., Dionne A., Frayne R., Genge A., Korngut L., Luk C., Zinman L., Kalra S.

PLoS One. 2022 June; 17 (6 June) 10.1371/journal.pone.0269154


Ishaque A., Ta D., Khan M., Zinman L., Korngut L., Genge A., Dionne A., Briemberg H., Luk C., Yang Y.H., Beaulieu C., Emery D., Eurich D.T., Frayne R., Graham S., Wilman A., Dupré N., Kalra S.

HUMAN BRAIN MAPPING. 2022 April; 43 (5):1519-1534 10.1002/hbm.25738


Kushol R., Masoumzadeh A., Huo D., Kalra S., Yang Y.H.

Proceedings - International Symposium on Biomedical Imaging. 2022 March; 2022-March 10.1109/ISBI52829.2022.9761421


Tanchip C., Guarin D.L., McKinlay S., Barnett C., Kalra S., Genge A., Korngut L., Green J.R., Berry J., Zinman L., Yadollahi A., Abrahao A., Yunusova Y.

Journal of Speech, Language, and Hearing Research. 2022 March; 65 (3):940-953 10.1044/2021_JSLHR-21-00503


Picher-Martel V., Magnussen C., Blais M., Bubela T., Das S., Dionne A., Evans A.C., Genge A., Greiner R., Iturria-Medina Y., Johnston W., Jones K., Kaneb H., Karamchandani J., Moradipoor S., Robertson J., Rogaeva E., Taylor D.M., Vande Velde C., Yunusova Y., Zinman L., Kalra S., Dupré N.

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022 January; 10.1080/21678421.2022.2041668


McMillan C.T., Wuu J., Rascovsky K., Cosentino S., Grossman M., Elman L., Quinn C., Rosario L., Stark J.H., Granit V., Briemberg H., Chenji S., Dionne A., Genge A., Johnston W., Korngut L., Shoesmith C., Zinman L., Kalra S., Benatar M.

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022 January; 10.1080/21678421.2022.2039713


Salmon K., Anoja N., Breiner A., Chum M., Dionne A., Dupré N., Fiander A., Fok D., Ghavanini A., Gosselin S., Izenberg A., Johnston W., Kalra S., Matte G., Melanson M., O’Connell C., Ritsma B., Schellenberg K., Shoesmith C., Tremblay S., Williams H., Genge A.

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022 January; 23 (3-4):305-312 10.1080/21678421.2021.1980890


Krieger C., Kalra S.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. 2022 January; 10.1017/cjn.2022.67


Proceedings - International Symposium on Biomedical Imaging. 2022 January; 10.1109/ISBI52829.2022.9761421


Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022 January; 10.1080/21678421.2022.2041668


Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2022 January; 10.1080/21678421.2022.2039713


Human Brain Mapping. 2022 January; 10.1002/hbm.25738


PLoS ONE. 2022 January; 10.1371/journal.pone.0269154


Canadian Journal of Neurological Sciences. 2022 January; 10.1017/cjn.2022.67


NeuroImage. 2022 January; 10.1016/j.neuroimage.2022.119180


Cleary S., Misiaszek J.E., Wheeler S., Kalra S., Genuis S.K., Johnston W.S.

MUSCLE & NERVE. 2021 December; 64 (6):676-682 10.1002/mus.27417


Ta D., Ishaque A., Srivastava O., Hanstock C., Seres P., Eurich D.T., Luk C., Briemberg H., Frayne R., Genge A.L., Graham S.J., Korngut L., Zinman L., Kalra S.

NEUROLOGY. 2021 August; 97 (8):e803-e813 10.1212/WNL.0000000000012367


Mapping cerebral abnormalities using texture analysis in ALS with T2-FLAIR MRI: a multicenter study

Organization for Human Brain Mapping. 2021 June;


MRI texture analysis for the prediction of survival in amyotrophic lateral sclerosis

Organization for Human Brain Mapping. 2021 June;


Texture analysis reveals cerebral degeneration in amyotrophic lateral sclerosis: a multicenter study

Organization for Human Brain Mapping. 2021 June;


Progressive neurochemical abnormalities in cognitive and motor subgroups of ALS: a multicenter study

Neurology. 2021 April;


The Comprehensive Analysis Platform To Understand, Remedy, and Eliminate ALS (CAPTURE ALS)

Neurology. 2021 April;


Dai Z., Kalra S., Mah D., Seres P., Sun H., Wu R., Wilman A.H.

EUROPEAN RADIOLOGY. 2021 March; 31 (3):1401-1409 10.1007/s00330-020-07243-4


Danyluk H., Ishaque A., Ta D., Yang Y.H., Wheatley B.M., Kalra S., Sankar T.

Frontiers in Neurology. 2021 February; 12 10.3389/fneur.2021.626504


Dey A., Assaedi E., Johnston W., Kalra S., Das S.

FOLIA NEUROPATHOLOGICA. 2021 January; 59 (4):403-408 10.5114/fn.2021.111486


Hodgkinson V., Lounsberry J., M'Dahoma S., Russell A., Jewett G., Benstead T., Brais B., Campbell C., Johnston W., Lochmuller H., McCormick A., Nguyen C.T., O'Ferrall E., Oskoui M., Abrahao A., Briemberg H., Bourque P.R., Botez S., Cashman N., Chapman K., Chrestian N., Crone M., Dobrowolski P., Dojeiji S., Dowling J.J., Dupre N., Genge A., Gonorazky H., Grant I., Hasal S., Izenberg A., Kalra S., Katzberg H., Krieger C., Leung E., Linassi G., Mackenzie A., Mah J.K., Marrero A., Massie R., Matte G., McAdam L., McMillan H., Melanson M., Mezei M.M., O'Connell C., Pfeffer G., Phan C., Plamondon S., Poulin C., Rodrigue X., Schellenberg K., Selby K., Sheriko J., Shoesmith C., Smith R.G., Taillon M., Taylor S., Venance S., Warman-Chardon J., Worley S., Zinman L., Korngut L.

Journal of Neuromuscular Diseases. 2021 January; 8 (1):53-61 10.3233/JND-200538


European Radiology. 2021 January; 10.1007/s00330-020-07243-4


arXiv. 2021 January;


Frontiers in Neurology. 2021 January; 10.3389/fneur.2021.626504


Folia Neuropathologica. 2021 January; 10.5114/fn.2021.111486


Brain Imaging and Behavior. 2021 January; 10.1007/s11682-020-00359-7


Neurology. 2021 January; 10.1212/WNL.0000000000012367


Journal of Neuromuscular Diseases. 2021 January; 10.3233/JND-200538


Canadian Best Practice Recommendations for the Management of ALS

ALS. 2020 December;


Clinical Characteristics of SOD1 and c9ORF72 positive ALS: Findings from the Canadian Neuromuscular Disease Registry

ALS. 2020 December;


Dentate nucleus structural and functional connectivity changes in Amyotrophic lateral sclerosis: A multicenter and multi-modal neuroimaging study

ALS. 2020 December;


Genetic testing for ALS in Canada - An assessment of current practices

ALS. 2020 December;


Impaired functional connectivity of the primary motor cortex is associated with underlying structural and neurochemical deficits: A multicentre-multimodal imaging approach to investigating ALS pathology

ALS. 2020 December;


The Comprehensive Analysis Platform To Understand, Remedy, and Eliminate ALS (CAPTURE ALS)

ALS. 2020 December;


Shoesmith C., Abrahao A., Benstead T., Chum M., Dupre N., Izenberg A., Johnston W., Kalra S., Leddin D., O’Connell C., Schellenberg K., Tandon A., Zinman L.

CANADIAN MEDICAL ASSOCIATION JOURNAL. 2020 November; 192 (46):E1453-E1468 10.1503/cmaj.191721


Chenji S., Ishaque A., Mah D., Fujiwara E., Beaulieu C., Seres P., Graham S.J., Frayne R., Zinman L., Genge A., Korngut L., Johnston W., Kalra S.

Brain Imaging and Behavior. 2020 November; 15 (3):1641-1654 10.1007/s11682-020-00359-7


Brain communications. 2020 May; 10.1093/braincomms/fcaa061


Neurology. 2020 January; 10.1212/WNL.0000000000010235


medRxiv. 2020 January; 10.1101/2020.12.23.20248410


Canadian Journal of Neurological Sciences. 2020 January; 10.1017/cjn.2020.19


CMAJ. 2020 January; 10.1503/cmaj.191721


NeuroImage: Clinical. 2020 January; 10.1016/j.nicl.2020.102385


Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2020 January; 10.1080/21678421.2019.1697888


Journal of Magnetic Resonance Imaging. 2020 January; 10.1002/jmri.26904


Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2020 January; 10.1080/21678421.2020.1727926


Computerized Medical Imaging and Graphics. 2020 January; 10.1016/j.compmedimag.2019.101659


medRxiv. 2020 January; 10.1101/2020.07.10.20142679


Neurology: Clinical Practice. 2019 January; 10.1212/CPJ.0000000000000674


Human Brain Mapping. 2019 January; 10.1002/hbm.24437


Frontiers in Neurology. 2019 January; 10.3389/fneur.2019.00482


Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 2019 January; 10.1080/21678421.2019.1599024


Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 2018 January; 10.1016/j.dadm.2018.09.002


Canadian Journal of Neurological Sciences. 2018 January; 10.1017/cjn.2018.311


Canadian Journal of Neurological Sciences. 2018 January; 10.1017/cjn.2018.267


Canadian Journal of Neurological Sciences. 2018 January; 10.1017/cjn.2018.68


arXiv. 2017 January;


Human Brain Mapping. 2017 January; 10.1002/hbm.23452


PloS one. 2016 February; 10.1371/journal.pone.0149622


Frontiers in Neuroscience. 2016 January; 10.3389/fnins.2016.00120


PLoS ONE. 2016 January; 10.1371/journal.pone.0157443


Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2015 January; 10.1007/978-3-319-16865-4_36


PLoS ONE. 2015 January; 10.1371/journal.pone.0117759


IEEE Transactions on Image Processing. 2014 January; 10.1109/TIP.2014.2351620


Journal of the Neurological Sciences. 2014 January; 10.1016/j.jns.2013.10.038


Pattern Recognition. 2013 January; 10.1016/j.patcog.2013.01.014


IEEE Transactions on Image Processing. 2013 January; 10.1109/TIP.2013.2249081


American Journal of Neuroradiology. 2011 January; 10.3174/ajnr.A2289


American Journal of Neuroradiology. 2011 January; 10.3174/ajnr.A2590


The Lancet Neurology. 2011 January; 10.1016/S1474-4422(11)70049-7


Amyotrophic Lateral Sclerosis. 2010 January; 10.3109/17482960902756473


European Journal of Neurology. 2010 January; 10.1111/j.1468-1331.2010.02951.x


Journal of Magnetic Resonance. 2009 January; 10.1016/j.jmr.2009.02.002


Neurology. 2009 January; 10.1212/WNL.0b013e3181bc01a4


Neurology. 2009 January; 10.1212/WNL.0b013e3181bc0141


Magnetic Resonance in Medicine. 2008 January; 10.1002/mrm.21450


Canadian Journal of Neurological Sciences. 2008 January; 10.1017/S0317167100009495


Magnetic Resonance in Medicine. 2007 January; 10.1002/mrm.21275


Journal of Neuroimaging. 2007 January; 10.1111/j.1552-6569.2007.00100.x


Journal of Neurology, Neurosurgery and Psychiatry. 2006 January; 10.1136/jnnp.2006.090696


Archives of Neurology. 2006 January; 10.1001/archneur.63.8.1144


Advances in Experimental Medicine and Biology. 2006 January; 10.1007/0-387-30172-0_19


Magnetic Resonance in Medicine. 2006 January; 10.1002/mrm.20988


Journal of Neurology. 2006 January; 10.1007/s00415-006-0162-7


Magnetic Resonance in Medicine. 2006 January; 10.1002/mrm.21055


Neurology. 2006 January; 10.1212/01.wnl.0000240062.10793.15


CMAJ. 2006 January; 10.1503/cmaj.060541


Canadian Journal of Neurological Sciences. 2006 January; 10.1017/S0317167100005448


Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2003 January; 10.1080/14660820310006689


American Journal of Neuroradiology. 2003 January;


Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2003 January; 10.1080/14660820310011269


Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 2002 January; 10.1080/146608202320374363


Journal of the Neurological Sciences. 1999 January; 10.1016/S0022-510X(99)00023-4


NeuroReport. 1998 January; 10.1097/00001756-199806010-00016


Archives of internal medicine. 1996 March; 10.1001/archinte.1996.00440050031004


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