Karen Doucette

Professor, Faculty of Medicine & Dentistry - Medicine Dept

Contact

Professor, Faculty of Medicine & Dentistry - Medicine Dept
Email
ked1@ualberta.ca
Phone
(780) 492-7686
Address
1-124J Clinical Sciences Building
11304 83 Ave NW
Edmonton AB
T6G 2G3

Overview

Area of Study / Keywords

immunocompromised hosts hepatitis B hepatitis C infectious complications of organ transplant donor derived infection


About

Divisional:  780-492-5936

Clinical:  780-492-7686


Dr. Doucette is Professor of Medicine and Division Director of Infectious Diseases. She completed her undergraduate (BSc) degree and MD at Dalhousie University in Halifax, Nova Scotia. Internal Medicine training at Queen’s University was followed by subspecialty training in Infectious Diseases at the University of Manitoba. While at University of Manitoba she undertook additional subspecialty training in viral hepatitis and liver disease. In 2003 she completed a clinical and research fellowship in Transplant Infectious Diseases at the Massachusetts General Hospital. In 2007 she completed a Master’s in Epidemiology at Harvard School of Public Health. She joined the University of Alberta in 2004 and in 2015, she was appointed Divisional Director.

Her clinical and research interests are in infections in immunocompromised hosts, particularly solid organ transplant recipients, and viral hepatitis. She was the Medical Director for the Infectious Diseases Hepatitis Support Program from 2006-April 2015 and led the Transplant Infectious Diseases Clinical Program from 2004 to 2008 as well as the Transplant ID Fellowship Program from 2008-2020. She has published over 60 peer reviewed manuscripts as well as authored or co- authored several book chapters and both national and international guidelines in the fields of transplantation and viral hepatitis. She has delivered many international and national scientific lectures, as well as over 200 CME sessions regionally and nationally. In 2016 she was inducted as a Fellow of the American Society of Transplantation and in 2021 was awarded the Canadian Society of Transplantation’s Clinician Recognition Award for contributions to program development, innovation and education, notably in the area of viral hepatitis and organ donation and transplantation.



Clinical Interests

Infections in immunocompromised hosts

Viral hepatitis


Research

  • Epidemiology and outcomes of infections in organ transplant recipients
  • Epidemiology and quality of care in viral hepatitis in immunocompromised and immune competent host
  • Clinical trials

Teaching

  • Clinical skills and small group learning in UGME/PGME
  • Education Lead, Transplant Infectious Diseases Fellowship
  • Alberta Transplant Institute, Education Committee Member
  • Royal College of Physicians & Surgeons of Canada Infectious Diseases Exam Board Member
  • Royal College of Physicians & Surgeons of Canada, Solid Organ Transplant Area of Focused Competence (AFC; diploma) Committee Member
  • Canadian Society of Transplantation, Education Committee

Featured Publications

Robbins M., Doucette K.

Transplant Infectious Disease. 2022 August; 24 (4) 10.1111/tid.13871


Infectious Complications in Biologic and Targeted Therapies. 2022 June; ISBN-13: 9783031113628


Effect of antiretroviral switch from TDF to TAF on ALT, lipid profile and renal function in HIV/HBV-coinfected individuals in a nationwide Canadian study

Canadian Liver Journal. 2022 May;


Osiowy C., Swidinsky K., Haylock-Jacobs S., Sadler M.D., Fung S., Wong D., Minuk G.Y., Doucette K.E., Wong P., Tam E., Cooper C., Ramji A., Ma M., Nudo C., Tsoi K., Coffin C.S.

J Hep Reports. 2022 May; 4 (5) 10.1016/j.jhepr.2022.100461


Chen J.Z., Hoang H.L., Yaskina M., Kabbani D., Doucette K.E., Smith S.W., Lau C., Stewart J., Zurek K., Schultz M., Cervera C.

PLoS One. 2022 March; 17 (3 March) 10.1371/journal.pone.0265493


Bégin P., Callum J., Cook R., Jamula E., Liu Y., Finzi A., Heddle N.M., Tinmouth A., Zeller M.P., Beaudoin-Bussières G., Amorim L., Bazin R., Loftsgard K.C., Carl R., Chassé M., Cushing M.M., Daneman N., Devine D.V., Dumaresq J., Fergusson D.A., Gabe C., Glesby M.J., Li N., McGeer A., Robitaille N., Sachais B.S., Scales D.C., Schwartz L., Shehata N., Turgeon A.F., Wood H., Zarychanski R., Arnold D.M., Marceau D., Huang A., Carr H., Lin Y., Lall R., Graham C., Arsenault C., Sales V., Sidhu D., Semret M., Hamm C., Arhanchiague E., Solh Z., Srour N., Soliman K., Yee C., Laroche V., Nahirniak S., Greenaway C., Pai M., Côté A., Tsang J.L.Y., Cserti-Gazdewich C., Talbot D., Poulin S., Guimaraes R., Rushton-Marovac M., Langlois A., Ning S., Shih A., Boileau M., Singh H., Ledingham D., Ponnampalam A., Yan M., Prokopchuk-Gauk O., Poirier A., Girouard G., Pavenski K., Drouin O., Harris D., Durand M., Rimmer E., Ovakim D., Ménard F., Cuccarolo G., Carruthers J., Lucier K., Arsenault V., Auclair M.C., Avram M., Brassard M., Cerro S., Martinez V., Morin J., Saint-Jacques M., Veillette M., Armali C., Kron A., Modi D., Duncan J., Justumus P., St John M., St-Onge G., Hadzi-Tosev M., Dion P.M., McGillivary L., Valleteau de Moulliac A., Nyman S.A., Perilli S., Van Vliet P.J., Lane S., Pereira R., Sirotich E., Abelson J., Greene S., Khandelwal A., Thakar S., Longo S., Anand S.P., Benlarbi M., Bourassa C., Boutin M., Descôteaux-Dinelle J., Gendron-Lepage G., Goyette G., Laumaea A., Medjahed H., Prévost J., Richard J., Kaufmann D., Brunet-Ratnasingham E., Chaumont N., Drebot M., Robinson A., Mendoza E., Dimitrova K., Manguiat K., Phillipson C., Chan M., Evans D., Lin J., Boyer L., Cloutier M., Drouin M., Ducas É., Dussault N., Fournier M.J., Landy P., Nolin M.È., Perreault J., Tremblay T., Nazy I., Xie F., Liu D., Wong M., Silverio G., Walkus K., Barton M., Haveman K., Mueller D., Scott A., Moher M., Wood G., Roarty T., Auld F., Carney G., Thomson V., Onell R., Walley K., Donohoe K., Brunk C., Hernandez G., Jacobucci T., Lazosky L., Mann P., Raval G., Zampieri L.A., Sekhon M., Wright A., James N., Chang G., Chen R., Deol K., Gantioqui J., Larsen E., Ramdin N., Roche M., Rosinski K., Sham L., Storms M., Gillrie M., Mahe E., Suryanarayan D., Ugarte-Torres A., Robinson T., Gibbs M., Hewsgirard J., Holmes M., McCarthy J., Ody M., Doucette K., Sligl W., Sonpar A., Robertson K., Narayan J., Ravindran L., Stewart B., Zapernick L., Lee S., Sy E., Wong A., Gryzb K., Craddock S., Fuchs D., Myrah D., Sunny S., Harding S.R., Kogilwaimath S., Hodgson N., Johnson D., Meier S., Thomson K., Heendeniya A., Houston B., Kenyan Y., Lother S., Olafson K., Rush B., Wuerz T., Solvason D., Albensi L., Alias S., Choi N., Curtis L., Hutmacher M., Kashani H., Lane D., Marten N., Pronyk-Ward T., Rigaux L., Silva R., Tays Q., Naidu R., Mathews J., Mai M., Miceli V., Molson L., Radhakrishnan G., Schaefer L., Haddad M., Landry S., Chernish R., Kruisselbrink R., Liu T., Jeromin J., Siddiqui A., Girolametto C., Krokoszynski K., Main C., Fox-Robichaud A., Rochwerg B., Kruja E., Ellingham D., Sampat D., Tang N., Leto D., Karunakaran M., Ricciuto D., Fusco K., Ghate T., Robinson H., Ball I., Shalhoub S., Slessarev M., Silverman M., Nano E., Bentall T., Campbell E., Kinney J., Parvathy S., Fera E., La Delfa A., Nadarajah J., Solow H., Engel K., Monaco D., Kononow L., Suntharalingam S., Fralick M., Munshi L., Saeed S., Hajjaj O., Hsu E., Ali K., Duan E., Farjou G., Jenson L., Salib M., Patterson L., Anant S., Ding J., Jomy J., Das P., Geagea A., Ingber S., Owen E., Lostun A., Albano T., Chatterjee A., Giraldo M., Hickey J., Lee I., Okada N., Pasquale N., Ponzielli R., Rahmat M., Sabur S., Schlag M., Aguiar L., Damani A., Hong S., Kokabi M., Perkins C., Cowan J., Giulivi T., MacFadden D., Cyr J., Pecarskie A., Porteous R., Vedder P.O., Watpool I., Berardi P., Bustani L., Graver A., Iyengar A., Kisilewicz M., et al

NATURE MEDICINE. 2022 January; 28 (1):53-58 10.1038/s41591-021-01639-5


Hernandez C., Mabilangan C., Burton C., Doucette K., Preiksaitis J.

AMERICAN JOURNAL OF TRANSPLANTATION. 2021 December; 21 (12):3958-3970 10.1111/ajt.16734


Bégin P., Callum J., Jamula E., Cook R., Heddle N.M., Tinmouth A., Zeller M.P., Beaudoin-Bussières G., Amorim L., Bazin R., Loftsgard K.C., Carl R., Chassé M., Cushing M.M., Daneman N., Devine D.V., Dumaresq J., Fergusson D.A., Gabe C., Glesby M.J., Li N., Liu Y., McGeer A., Robitaille N., Sachais B.S., Scales D.C., Schwartz L., Shehata N., Turgeon A.F., Wood H., Zarychanski R., Finzi A., Marceau D., Huang A., Carr H., Lin Y., Lall R., Graham C., Arsenault C., Sales V., Sidhu D., Semret M., Hamm C., Arhanchiague E., Solh Z., Srour N., Soliman K., Yee C., Laroche V., Nahirniak S., Greenaway C., Pai M., Côté A., Tsang J.L.Y., Cserti-Gazdewich C., Talbot D., Poulin S., Guimaraes R., Rushton-Marovac M., Langlois A., Ning S., Shih A., Boileau M., Singh H., Ledingham D., Ponnampalam A., Yan M., Prokopchuk-Gauk O., Poirier A., Girouard G., Pavenski K., Drouin O., Harris D., Durand M., Rimmer E., Ovakim D., Ménard F., Cuccarolo G., Carruthers J., Lucier K., Auclair M.C., Avram M., Brassard M., Cerro S., Martinez V., Morin J., Saint-Jacques M., Veillette M., Armali C., Kron A., Modi D., Duncan J., Justumus P., John M.S., St-Onge G., Hadzi-Tosev M., Dion P.M., McGillivary L., de Moulliac A.V., Nyman S.A., Perilli S., Van Vliet P.J., Lane S., Pereira R., Sirotich E., Abelson J., Greene S., Khandelwal A., Thakar S., Longo S., Anand S.P., Benlarbi M., Bourassa C., Boutin M., Descôteaux-Dinelle J., Gendron-Lepage G., Goyette G., Laumaea A., Medjahed H., Prévost J., Richard J., Kaufmann D., Brunet-Ratnasingham E., Chaumont N., Drebot M., Robinson A., Mendoza E., Dimitrova K., Manguiat K., Phillipson C., Chan M., Evans D., Lin J., Boyer L., Cloutier M., Drouin M., Ducas É., Dussault N., Fournier M.J., Landy P., Nolin M.È., Perreault J., Tremblay T., Nazy I., Xie F., Liu D., Wong M., Silverio G., Walkus K., Barton M., Haveman K., Mueller D., Scott A., Moher M., Wood G., Roarty T., Auld F., Carney G., Thomson V., Onell R., Walley K., Donohoe K., Brunk C., Hernandez G., Jacobucci T., Lazosky L., Mann P., Raval G., Zampieri L.A., Sekhon M., Wright A., James N., Chang G., Chen R., Deol K., Gantioqui J., Larsen E., Ramdin N., Roche M., Rosinski K., Sham L., Storms M., Gillrie M., Mahe E., Suryanarayan D., Ugarte-Torres A., Robinson T., Gibbs M., Hewsgirard J., Holmes M., McCarthy J., Ody M., Doucette K., Sligl W., Sonpar A., Robertson K., Narayan J., Ravindran L., Stewart B., Zapernick L., Lee S., Sy E., Wong A., Gryzb K., Craddock S., Fuchs D., Myrah D., Sunny S., Harding S.R., Kogilwaimath S., Hodgson N., Johnson D., Meier S., Thomson K., Heendeniya A., Houston B., Kenyan Y., Lother S., Olafson K., Rush B., Wuerz T., Solvason D., Albensi L., Alias S., Choi N., Curtis L., Hutmacher M., Kashani H., Lane D., Marten N., Pronyk-Ward T., Rigaux L., Silva R., Tays Q., Naidu R., Mathews J., Mai M., Miceli V., Molson L., Radhakrishnan G., Schaefer L., Haddad M., Landry S., Chernish R., Kruisselbrink R., Liu T., Jeromin J., Siddiqui A., Girolametto C., Krokoszynski K., Main C., Fox-Robichaud A., Rochwerg B., Kruja E., Ellingham D., Sampat D., Tang N., Leto D., Karunakaran M., Ricciuto D., Fusco K., Ghate T., Robinson H., Ball I., Shalhoub S., Slessarev M., Silverman M., Nano E., Bentall T., Campbell E., Kinney J., Parvathy S., Fera E., Delfa A.L., Nadarajah J., Solow H., Mendoza E., Engel K., Monaco D., Kononow L., Suntharalingam S., Fralick M., Munshi L., Saeed S., Hajjaj O., Hsu E., Ali K., Duan E., Farjou G., Jenson L., Salib M., Patterson L., Anant S., Ding J., Jomy J., Das P., Geagea A., Ingber S., Owen E., Lostun A., Albano T., Chatterjee A., Giraldo M., Hickey J., Lee I., Okada N., Pasquale N., Ponzielli R., Rahmat M., Sabur S., Schlag M., Aguiar L., Damani A., Hong S., Kokabi M., Perkins C., Cowan J., Giulivi T., MacFadden D., Cyr J., Pecarskie A., Porteous R., Vedder P.O., Watpool I., Berardi P. et al

NATURE MEDICINE. 2021 November; 27 (11):2012-2024 10.1038/s41591-021-01488-2


Li D., Abele J., Weinkauf J., Kapasi A., Hirji A., Varughese R., Nagendran J., Lien D., Doucette K., Halloran K.

CLINICAL TRANSPLANTATION. 2021 July; 35 (7) 10.1111/ctr.14315


Prescribing pattern of restricted antimicrobials at a quaternary care academic hospital

Journal of the Association of Medical Microbiology and Infectious Disease Canada. 2021 July;


Stepwise implementation of an antimicrobial stewardship prospective audit and feedback intervention at a large academic centre in Canada

Journal of the Association of Medical Microbiology and Infectious Disease Canada. 2021 July;


Friedman D.Z.P., Doucette K.

SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE. 2021 June; 42 (3):460-470 10.1055/s-0041-1727250


Farag M.S., Fung S., Tam E., Doucette K., Wong A., Ramji A., Conway B., Cooper C., Tsoi K., Wong P., Sebastiani G., Brahmania M., Haylock-Jacobs S., Coffin C.S., Hansen B.E., Janssen H.L.A.

JOURNAL OF VIRAL HEPATITIS. 2021 June; 28 (6):942-950 10.1111/jvh.13500


An Investigation of Novel Hepatitis B Virus Quantitative Serum Biomarkers in Hepatitis B-Hepatitis D Co-Infected Patients Enrolled in the Canadian Hepatitis B Network

Canadian Liver Meeting. 2021 May;


Clinical and virologic characteristics and hepatitis B surface antigen levels in a multi-ethnic cohort of patients with chronic hepatitis B to identify high-risk patient populations

Canadian Liver Meeting. 2021 May;


Systemic Cytokine Levels and T Cell Responses in Patients with Chronic Hepatitis B and Comorbid Non-Alcoholic Fatty Liver Disease

Canadian Liver Meeting. 2021 May;


Prescribing pattern of restricted antimicrobials at a quaternary care academic hospital

Journal of the Association of Medical Microbiology and Infectious Diseases. 2021 April;


Stepwise implementation of an antimicrobial stewardship prospective audit and feedback intervention at a large academic centre in Canada

Journal of the Association of Medical Microbiology and Infectious Diseases. 2021 April;


Cooper C., Driedger M., Wong D., Haylock-Jacobs S., Aziz Shaheen A., Osiowy C., Fung S., Doucette K., Wong A., Barrett L., Conway B., Ramji A., Minuk G., Sebastiani G., Wong P., Coffin C.S.

JOURNAL OF VIRAL HEPATITIS. 2021 March; 28 (3):517-527 10.1111/jvh.13453


Parmar P., Shafran S.D., Borgia S.M., Doucette K., Cooper C.L.

JGH Open. 2021 February; 5 (2):253-257 10.1002/jgh3.12480


Hernandez C., Mabilangan C., Burton C., Doucette K., Preiksaitis J.

AMERICAN JOURNAL OF TRANSPLANTATION. 2021 January; 10.1111/ajt.16734


Weyant R.B., Kabbani D., Doucette K., Lau C., Cervera C.

EXPERT OPINION ON PHARMACOTHERAPY. 2021 January; 10.1080/14656566.2021.1915989


Parmar P., Shafran S.D., Borgia S.M., Doucette K., Cooper C.L.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2020 December; 5 10.1002/jgh3.12480


Epidemiologic, clinical and treatment factors of hepatocellular carcinoma in patients with chronic hepatitis B: A descriptive study from the Canadian Hepatitis B Network

Hepatology Volume 72, Issue S1; Nov 2020. 2020 November;