Paul Major

Professor, Faculty of Medicine & Dentistry - Dentistry Dept
Chair, Faculty of Medicine & Dentistry - Dentistry Dept


Professor, Faculty of Medicine & Dentistry - Dentistry Dept
(780) 492-3312
5-478 Edmonton Clinic Health Academy
11405 87 Ave NW
Edmonton AB
T6G 1C9

Chair, Faculty of Medicine & Dentistry - Dentistry Dept
(780) 492-3312


Area of Study / Keywords

Orthodontic Biomechanics Ultrasound Imaging 3D Craniofacial Imaging


Dr. Major completed his Doctorate of Dental Surgery (DDS) at the University of Alberta in 1980. He went on to complete MSc degree and Orthodontic Specialty training at the University of Alberta in 1988. Dr. Major accepted an academic appointment at the University of Alberta in 1989, and has served as Director of the postgraduate TMD/Orofacial Pain Program from 1991-2001 and as Director of the Orthodontic Graduate Program from 2001-2010. He presently serves as the Professor and Chair, School of Dentistry and Senior Associate Dean (Dental Affairs) at the University of Alberta. 

 During his academic career, he has published more than 190 publications and supervised the research of more than 75 graduate students. He has presented many lectures at national and international forums. In addition to his responsibilities as Chair of the School of Dentistry, he is continuing with clinical teaching and graduate student research supervision. 


  • Development and validation of 3D reconstructed images of the craniofacial complex
  • Application of diagnostic ultrasound imaging of the periodontal complex 
  • Orthodontic Biomechanics Research Group - Analysis and prediction of complex orthodontic force systems
    • We have designed, constructed and calibrated an orthodontic simulations system (OSIM) that allows measurement of 3D forces and moments acting simultaneously on all 14 teeth engaged in an orthodontic appliance such as an archwire. We are conducting a series of experiments to analyze force prorogation around the dental arch with various wire/bracket systems in specific malocclusions. We are also conducting a series of experiments to analyze force systems associated with clear aligner orthodontic treatment. 
    • We have designed an experimental device to measure in-sit bracket/wire deformation and stress, using high magnification imaging optics and CCD camera system. This is being applied in a series of experiments investigating torque and friction.
  • Inter-disciplinary Airway Research Clinic (I-ARC) 
    Our interdisciplinary team (pediatric ENT, pediatric pulmonology, radiology, orthodontics, biomedical engineering) evaluate and treat children with sleep disordered breathing (including obstructive sleep apnea). Within this context of patient care we are conducting several research projects including:
    • Evaluation of craniofacial morphology in relation to sleep disordered breathing
    • Evaluation of orthodontic interventions within an interdisciplinary care model
    • Evaluation of CBCT against naso-endoscopy to screen patients at risk for upper airway anatomic insufficiency 
    • Evaluation of autosegmentation software application for airway measurements from CBCT images

Featured Publications

Rafiee A., Carvalho R., Lunardon D., Flores-Mir C., Major P., Quemerais B., Altabtbaei K.

JOURNAL OF DENTAL RESEARCH. 2022 July; 101 (7):785-792 10.1177/00220345221087880

Pan M., Nguyen K.C.T., Yang W., Liu X., Chen X.Z., Major P.W., Le L.H., Zeng H.

Chemical Engineering Journal. 2022 April; 434 10.1016/j.cej.2021.134418

Alsufyani N.A., Major M.P., Major P.W.

BioMed Research International. 2022 January; 2022 10.1155/2022/4651514

Houg K.P., Camarillo A.M., Doschak M.R., Major P.W., Popowics T., Dennison C.R., Romanyk D.L.

JOURNAL OF DENTAL RESEARCH. 2022 January; 10.1177/00220345221100234

Fernandes Fagundes N.C., Carlyle T., Dalci O., Darendeliler M.A., Kornerup I., Major P.W., Montpetit A., Pliska B.T., Quo S., Heo G., Flores Mir C.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2022 January; 18 (1):57-66 10.5664/jcsm.9490

Kaur H., Truong J., Heo G., Mah J.K., Major P.W., Romanyk D.L.

AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS. 2021 September; 160 (3):401-409 10.1016/j.ajodo.2021.04.005

Nguyen K.C.T., Le B.M., Li M., Almeida F.T., Major P.W., Kaipatur N.R., Lou E.H.M., Punithakumar K., Le L.H.

Journal of Dentistry. 2021 September; 112 10.1016/j.jdent.2021.103752

Nguyen K.C.T., Yan Y., Kaipatur N.R., Major P.W., Lou E.H., Punithakumar K., Le L.H.

Applied Sciences (Switzerland). 2021 July; 11 (13) 10.3390/app11135850

Saltaji H., Armijo-Olivo S., Cummings G.G., Amin M., Major P.W., da Costa B.R., Flores-Mir C.

Journal of Evidence Based Dental Practice. 2021 June; 21 (2) 10.1016/j.jebdp.2021.101544

Kim J.J., Lagravere M.O., Kaipatur N.R., Major P.W., Romanyk D.L.

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2021 April; 131 (4):485-493 10.1016/j.oooo.2020.08.014

Chifor R, Li M, Nguyen KC, Arsenescu T, Chifor I, Badea AR, Badea ME, Hotolenu M, Major PW, Le LH

Medical Ultrasonography. 2021 March; 10.11152/mu-2837w

Tran B., Nobes D.S., Major P.W., Carey J.P., Romanyk D.L.

Journal of the Mechanical Behavior of Biomedical Materials. 2021 February; 114 10.1016/j.jmbbm.2020.104196

Alsufyani N., El-Hakim H., Major P.

Clinical Oral Investigations. 2021 January; 10.1007/s00784-021-03854-3

Yi J., Nguyen K.C.T., Wang W., Yang W., Pan M., Lou E., Major P.W., Le L.H., Zeng H.

ACS Applied Bio Materials. 2020 December; 3 (12):8943-8952 10.1021/acsabm.0c01211

Yi J., Nguyen K.C.T., Wang W., Yang W., Pan M., Lou E., Major P.W., Le L.H., Zeng H.

JOURNAL OF COLLOID AND INTERFACE SCIENCE. 2020 October; 578 10.1016/j.jcis.2020.06.015

Nguyen K.C.T., Duong D.Q., Almeida F.T., Major P.W., Kaipatur N.R., Pham T.T., Lou E.H.M., Noga M., Punithakumar K., Le L.H.

Journal of Dental Research. 2020 August; 99 (9):1054-1061 10.1177/0022034520920593