Piushkumar Mandhane

Professor, Faculty of Medicine & Dentistry - Pediatrics Dept

Contact Overview Publications

Contact

Professor, Faculty of Medicine & Dentistry - Pediatrics Dept

Email: mandhane@ualberta.ca
Phone: (780) 248-5650

Overview

Area of Study / Keywords

About

Dr. Piushkumar Mandhane is currently appointed as Associate Professor in the Department of Pediatrics in the Faculty of Medicine & Dentistry.

Featured Publications

Wheeze trajectories: Determinants and outcomes in the CHILD Cohort Study

Dai R., Miliku K., Gaddipati S., Choi J., Ambalavanan A., Tran M.M., Reyna M., Sbihi H., Lou W., Parvulescu P., Lefebvre D.L., Becker A.B., Azad M.B., Mandhane P.J., Turvey S.E., Duan Q., Moraes T.J., Sears M.R., Subbarao P.

Journal of Allergy and Clinical Immunology. 2022 June; 149 (6):2153-2165 10.1016/j.jaci.2021.10.039

DNA methylation changes in cord blood and the developmental origins of health and disease - a systematic review and replication study

Akhabir L., Stringer R., Desai D., Mandhane P.J., Azad M.B., Moraes T.J., Subbarao P., Turvey S.E., Paré G., Anand S.S., Anand S.S., Atkinson S., Azad M.B., Becker A.B., Brook J., Denburg J.A., de Souza R.J., Gupta M., Kobor M., Lefebvre D.L., Lou W., Mandhane P.J., McDonald S., Mente A., Meyre D., Moraes T.J., Morrison K., Sears M.R., Teo K.K., Turvey S.E., Wilson J., Yusuf S., Atkinson S., Wahi G., Zulyniak M.A.

BMC Genomics. 2022 March; 23 (1) 10.1186/s12864-022-08451-6

Assessing secondhand and thirdhand tobacco smoke exposure in Canadian infants using questionnaires, biomarkers, and machine learning

Parks J., McLean K.E., McCandless L., de Souza R.J., Brook J.R., Scott J., Turvey S.E., Mandhane P.J., Becker A.B., Azad M.B., Moraes T.J., Lefebvre D.L., Sears M.R., Subbarao P., Takaro T.K.

Journal of Exposure Science and Environmental Epidemiology. 2022 January; 32 (1):112-123 10.1038/s41370-021-00350-4

Bacteroides-dominant gut microbiome of late infancy is associated with enhanced neurodevelopment

Tamana S.K., Tun H.M., Konya T., Chari R.S., Field C.J., Guttman D.S., Becker A.B., Moraes T.J., Turvey S.E., Subbarao P., Sears M.R., Pei J., Scott J.A., Mandhane P.J., Kozyrskyj A.L.

Gut Microbes. 2022 January; 13 (1):1-17 10.1080/19490976.2021.1930875

Early-life cytomegalovirus infection is associated with gut microbiota perturbations and increased risk of atopy

Sbihi H., Simmons K.E., Sears M.R., Moraes T.J., Becker A.B., Mandhane P.J., Subbarao P., Dai D.L.Y., Finlay B.B., Turvey S.E., Gantt S.

Pediatric Allergy and Immunology. 2022 January; 33 (1) 10.1111/pai.13658

Lung clearance index predicts persistence of preschool wheeze

Safavi S., Dai R., Breton V.L., Emmerson M.N., Kowalik K., Lu Z., Lou W., Dubeau A., DeLorenzo S., Azad M.B., Becker A.B., Mandhane P.J., Turvey S.E., Gustafsson P., Lefebvre D.L., Sears M.R., Moraes T.J., Subbarao P.

Pediatric Allergy and Immunology. 2022 January; 33 (1) 10.1111/pai.13713

Development of a pediatric obstructive sleep apnea triage algorithm

Heath D.S., El-Hakim H., Al-Rahji Y., Eksteen E., Uwiera T.C., Isaac A., Castro-Codesal M., Gerdung C., Maclean J., Mandhane P.J.

Journal of Otolaryngology - Head and Neck Surgery. 2021 December; 50 (1) 10.1186/s40463-021-00528-8

Factors associated with breastfeeding initiation and continuation in Canadian-born and non-Canadian-born women: A multi-centre study

Chooniedass R., Tarrant M., Turner S., Lok Fan H.S., Del Buono K., Masina S., Becker A.B., Mandhane P.J., Turvey S.E., Moraes T.J., Sears M.R., Subbarao P., Azad M.B.

Public Health Nutrition. 2021 December; 10.1017/S1368980021004699

Development of a conceptual model of childhood asthma to inform asthma prevention policies

Adibi A., Turvey S.E., Lee T.Y., Sears M.R., Becker A.B., Mandhane P.J., Moraes T.J., Subbarao P., Sadatsafavi M.

BMJ Open Respiratory Research. 2021 November; 8 (1) 10.1136/bmjresp-2021-000881

Breastfeeding in the first days of life is associated with lower blood pressure at 3 years of age

Miliku K., Moraes T.J., Becker A.B., Mandhane P.J., Sears M.R., Turvey S.E., Subbarao P., Azad M.B.

Journal of the American Heart Association. 2021 August; 10 (15) 10.1161/JAHA.120.019067

Impact of maternal intrapartum antibiotics, and caesarean section with and without labour on bifidobacterium and other infant gut microbiota

Chen Y.Y., Zhao X., Moeder W., Tun H.M., Simons E., Mandhane P.J., Moraes T.J., Turvey S.E., Subbarao P., Scott J.A., Kozyrskyj A.L.

Microorganisms. 2021 August; 9 (9) 10.3390/microorganisms9091847

Sex-specific associations of human milk long-chain polyunsaturated fatty acids and infant allergic conditions

Miliku K., Richelle J., Becker A.B., Simons E., Moraes T.J., Stuart T.E., Mandhane P.J., Sears M.R., Subbarao P., Field C.J., Azad M.B.

Pediatric Allergy and Immunology. 2021 August; 32 (6):1173-1182 10.1111/pai.13500

World Health Organization growth standards: How do Canadian children measure up?

Rodd C., Feely A., Becker A.B., Moraes T.J., Subbarao P., Mandhane P.J., Turvey S.E., Lefebvre D.L., Sears M.R., Azad M.B., Sharma A.

Paediatrics and Child Health (Canada). 2021 August; 26 (5):E208-E214 10.1093/pch/pxaa053

Early Life Exposure to Tris(2-butoxyethyl) Phosphate (TBOEP) Is Related to the Development of Childhood Asthma

Navaranjan G., Jantunen L.M., Diamond M.L., Harris S.A., Bernstein S., Scott J.A., Takaro T.K., Dai R., Lefebvre D.L., Mandhane P.J., Moraes T.J., Simons E., Turvey S.E., Sears M.R., Subbarao P., Brook J.R.

Environmental Science and Technology Letters. 2021 July; 8 (7):531-537 10.1021/acs.estlett.1c00210

Ethnicity Associations With Food Sensitization Are Mediated by Gut Microbiota Development in the First Year of Life

Tun H.M., Peng Y., Chen B., Konya T.B., Morales-Lizcano N.P., Chari R., Field C.J., Guttman D.S., Becker A.B., Mandhane P.J., Moraes T.J., Sears M.R., Turvey S.E., Subbarao P., Simons E., Scott J.A., Kozyrskyj A.L.

Gastroenterology. 2021 July; 161 (1):94-106 10.1053/j.gastro.2021.03.016

Early life exposure to phthalates and the development of childhood asthma among Canadian children

Navaranjan G., Diamond M.L., Harris S.A., Jantunen L.M., Bernstein S., Scott J.A., Takaro T.K., Dai R., Lefebvre D.L., Azad M.B., Becker A.B., Mandhane P.J., Moraes T.J., Simons E., Turvey S.E., Sears M.R., Subbarao P., Brook J.R.

Environmental Research. 2021 June; 197 10.1016/j.envres.2021.110981

A rich meconium metabolome in human infants is associated with early-life gut microbiota composition and reduced allergic sensitization

Petersen C., Dai D.L.Y., Boutin R.C.T., Sbihi H., Sears M.R., Moraes T.J., Becker A.B., Azad M.B., Mandhane P.J., Subbarao P., Turvey S.E., Finlay B.B.

Cell Reports Medicine. 2021 May; 2 (5) 10.1016/j.xcrm.2021.100260

Risk of asthma in children diagnosed with bronchiolitis during infancy: Protocol of a longitudinal cohort study linking emergency department-based clinical data to provincial health administrative databases

Abdullah K., Fell D.B., Radhakrishnan D., Hawken S., Johnson D.W., Mandhane P., To T., Joubert G., Plint A.C.

BMJ open. 2021 May; 11 (5) 10.1136/bmjopen-2021-048823

Antibody Kinetics in RT-PCR Positive Children for SARS-CoV-2; 2021

UofA Pediatrics Research Day. 2021 May;

Influence of Neighborhood Characteristics and Weather on Movement Behaviors at Age 3 and 5 Years in a Longitudinal Birth Cohort

Ezeugwu V.E., Mandhane P.J., Hammam N., Brook J.R., Tamana S.K., Hunter S., Chikuma J., Lefebvre D.L., Azad M.B., Moraes T.J., Subbarao P., Becker A.B., Turvey S.E., Rosu A., Sears M.R., Carson V.

Journal of Physical Activity and Health. 2021 May; 18 (5):571-579 10.1123/JPAH.2020-0827

Prenatal egg consumption and infant sensitization and allergy to egg, peanut, and cow's milk in the CHILD Cohort

Loewen K., Moraes T.J., Turvey S.E., Mandhane P.J., Sears M.R., Subbarao P., Becker A.B., Azad M.B., Simons E.

Journal of Allergy and Clinical Immunology: In Practice. 2021 May; 9 (5):2109-2112.e2 10.1016/j.jaip.2020.11.061

Development and Validation of SDBeasy Score as a Predictor of Behavioral Outcomes in Childhood

van Eeden C., Tamana S.K., Narang I., Hammam N., Chikuma J., Lefebvre D.L., Azad M.B., Moraes T.J., Subbarao P., Becker A.B., Turvey S.E., Sears M.R., Rasmussen C., Pei J., Mandhane P.J.

American Journal of Respiratory and Critical Care Medicine. 2021 March; 203 (6):718-725 10.1164/rccm.202002-0363OC

Assessing secondhand and thirdhand tobacco smoke exposure in Canadian infants using questionnaires, biomarkers, and machine learning

Parks J., McLean K.E., McCandless L., de Souza R.J., Brook J.R., Scott J., Turvey S.E., Mandhane P.J., Becker A.B., Azad M.B., Moraes T.J., Lefebvre D.L., Sears M.R., Subbarao P., Takaro T.K.

Journal of Exposure Science and Environmental Epidemiology. 2021 January; 10.1038/s41370-021-00350-4

Bacterial-fungal interactions in the neonatal gut influence asthma outcomes later in life

Boutin R.C.T., Petersen C., Woodward S.E., Serapio-Palacios A., Bozorgmehr T., Loo R., Chalanuchpong A., Cirstea M., Lo B., Huus K.E., Barcik W., Azad M.B., Becker A.B., Mandhane P.J., Moraes T.J., Sears M.R., Subbarao P., McNagny K.M., Turvey S.E., Finlay B.B.

eLife. 2021 January; 10 10.7554/ELIFE.67740

Bacteroides-dominant gut microbiome of late infancy is associated with enhanced neurodevelopment

Tamana S.K., Tun H.M., Konya T., Chari R.S., Field C.J., Guttman D.S., Becker A.B., Moraes T.J., Turvey S.E., Subbarao P., Sears M.R., Pei J., Scott J.A., Mandhane P.J., Kozyrskyj A.L.

Gut Microbes. 2021 January; 13 (1):1-17 10.1080/19490976.2021.1930875

Composition and associations of the infant gut fungal microbiota with environmental factors and childhood allergic outcomes

Boutin R.C.T., Sbihi H., McLaughlin R.J., Hahn A.S., Konwar K.M., Loo R.S., Dai D., Petersen C., Brinkman F.S.L., Winsor G.L., Sears M.R., Moraes T.J., Becker A.B., Azad M.B., Mandhane P.J., Subbarao P., Turvey S.E., Finlay B.B.

mBio. 2021 January; 12 (3) 10.1128/mBio.03396-20

From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome

Vu K., Lou W., Tun H.M., Konya T.B., Morales-Lizcano N., Chari R.S., Field C.J., Guttman D.S., Mandal R., Wishart D.S., Azad M.B., Becker A.B., Mandhane P.J., Moraes T.J., Lefebvre D.L., Sears M.R., Turvey S.E., Subbarao P., Scott J.A., Kozyrskyj A.L.

Gastroenterology. 2021 January; 160 (1):128-144.e10 10.1053/j.gastro.2020.08.053

Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index

Laforest-Lapointe I., Becker A.B., Mandhane P.J., Turvey S.E., Moraes T.J., Sears M.R., Subbarao P., Sycuro L.K., Azad M.B., Arrieta M.C.

Gut Microbes. 2021 January; 13 (1):1-15 10.1080/19490976.2020.1857513

The relationship between machine-learning-derived sleep parameters and behavior problems in 3- And 5-year-old children: Results from the CHILD Cohort study

Hammam N., Sadeghi D., Carson V., Tamana S.K., Ezeugwu V.E., Chikuma J., Van Eeden C., Brook J.R., Lefebvre D.L., Moraes T.J., Subbarao P., Becker A.B., Turvey S.E., Sears M.R., Mandhane P.J.

Sleep. 2020 December; 43 (12) 10.1093/sleep/zsaa117

Vitamin D supplementation in pregnancy and early infancy in relation to gut microbiota composition and C. difficile colonization: implications for viral respiratory infections

Drall K.M., Field C.J., Haqq A.M., de Souza R.J., Tun H.M., Morales-Lizcano N.P., Konya T.B., Guttman D.S., Azad M.B., Becker A.B., Lefebvre D.L., Mandhane P.J., Moraes T.J., Sears M.R., Turvey S.E., Subbarao P., Scott J.A., Kozyrskyj A.L.

Gut Microbes. 2020 November; 12 (1) 10.1080/19490976.2020.1799734

Cardiorespiratory Monitoring Data during Sleep in Healthy Canadian Infants

Zina K.V., Mariasine J., Young R., Reyna M., Lu Z., Subbarao P., Moraes T.J., Becker A.B., Turvey S.E., Sears M.R., Lefebvre D.L., Azad M.B., Rasmussen C., Pei J., Narang I., Mandhane P.J.

Annals of the American Thoracic Society. 2020 October; 17 (10):1238-1246 10.1513/AnnalsATS.201909-703OC

Maternal diet and the serum metabolome in pregnancy: Robust dietary biomarkers generalizable to a multiethnic birth cohort

de Souza R.J., Shanmuganathan M., Lamri A., Atkinson S.A., Becker A., Desai D., Gupta M., Mandhane P.J., Moraes T.J., Morrison K.M., Subbarao P., Teo K.K., Turvey S.E., Williams N.C., Britz-McKibbin P., Anand S.S.

Current Developments in Nutrition. 2020 October; 4 (10) 10.1093/cdn/nzaa144

Sleep, circadian rhythm, and gut microbiota

Matenchuk B.A., Mandhane P.J., Kozyrskyj A.L.

Sleep Medicine Reviews. 2020 October; 53 10.1016/j.smrv.2020.101340

Natural environments in the urban context and gut microbiota in infants

Nielsen C.C., Gascon M., Osornio-Vargas A.R., Shier C., Guttman D.S., Becker A.B., Azad M.B., Sears M.R., Lefebvre D.L., Moraes T.J., Turvey S.E., Subbarao P., Takaro T.K., Brook J.R., Scott J.A., Mandhane P.J., Tun H.M., Kozyrskyj A.L.

Environment International. 2020 September; 142 10.1016/j.envint.2020.105881