Marcelo Marcet-Palacios

Area of Study / Keywords

HIV-1 COPD CABS1 stress genetics

About

Dr. Marcelo Marcet-Palacios is currently appointed as Assistant Adjunct Professor in the Department of Medicine in the Faculty of Medicine & Dentistry.

Research

My lab is interested in the structure-function relationships that enable biological systems. Our work on the superstructure of the HIV-1 matrix (MA) shell helped us predict a new model (1, 2) of viral entry facilitating our efforts to improve understanding of the biology of this pathogen.

To access computational resources developed for this project please follow the link below:

https://sites.ualberta.ca/~marcelo/HIV-1_MA_Builder

I also work closely with Dr. Dean Befus and currently co-supervise 2 graduate students. We have co-authored several publications on the biology of a novel biomarker, CABS1. This protein is expressed in several human tissues including testes, salivary glands, and lung epithelium. We believe that CABS1 functions as a systemic pro-hormone with the ability to regulate inflammation in organs such as the lungs. Studies conducted in animal models show promising results on the anti-inflammatory effects of human CABS1.