Mostafa Khaled Abo El Ella Abd El-Aziz

Contact

Grad Research Asst Fellowship, Faculty of Pharmacy & Pharmaceutical Sciences

Email: mostafak@ualberta.ca

Overview

Area of Study / Keywords

Cardiovascular Pharmacology Toxicology Pharmacogenomics Epigenetics

Research

My research expertise lies in molecular pharmacology, toxicology, and clinical pharmacogenomics, with hands-on experience in animal models and molecular techniques investigating inflammation, oxidative stress, and drug response. I am particularly interested in the role of CYP enzymes and environmental modulators in cardiovascular health, with a current focus on how postmenopausal physiological changes influence CYP-mediated pathways and cardiovascular risk. My goal is to integrate mechanistic pharmacology with translational research to better understand disease susceptibility and therapeutic outcomes.

Featured Publications

Down-regulation of TNF-α/RIPK/Caspase-8 axis by combined infliximab and umbelliferone prevents unilateral ureter ligation-induced interstitial renal fibrosis

Maha Habash, Zainab H. Almansour, Rasha K. Al-Akeel, Mohammad Bani Ismail, Duaa Althumairy, Hamad Abu Zahra, Tarek Hamdy Abd-Elhamid, Osama M. Ghogar, Mahmoud M. Ali, Mostafa K. Abd El-Aziz, Elham I. Sharab, Heba F. Khader, Amany Refaat Mahmoud, Fares E.M. Ali

Journal of Pharmacological Sciences. 2025 September; 10.1016/j.jphs.2025.06.003

Emotional stress and cardiovascular health: Impacts on neurodegenerative disease progression

Mostafa K. Abd El-Aziz, Al-Hassan Soliman Wadan, Abdelrahman T.I. Albahttiti, Nasrollah Moradikor

Progress in Brain Research. 2025 January; 10.1016/bs.pbr.2025.04.004

The melatonin receptor agonist agomelatine protects against acute pancreatitis induced by cadmium by attenuating inflammation and oxidative stress and modulating Nrf2/HO-1 pathway

Reem S. Alruhaimi, Emad H.M. Hassanein, Mostafa K. Abd El-Aziz, Maisa Siddiq Abduh, Albandari Bin-Ammar, Emadeldin M. Kamel, Ayman M. Mahmoud

International Immunopharmacology. 2023 November; 10.1016/j.intimp.2023.110833

Decoding hepatocarcinogenesis from a noncoding RNAs perspective

Mostafa K. Abd El‐Aziz, Alyaa Dawoud, Caroline J. Kiriacos, Sherif Ashraf Fahmy, Nadia M. Hamdy, Rana A. Youness

Journal of Cellular Physiology. 2023 September; 10.1002/jcp.31076

Rs205764 and rs547311 in linc00513 may influence treatment responses in multiple sclerosis patients: A pharmacogenomics Egyptian study

Nada Sherif Amin, Mostafa K. Abd El-Aziz, Mohamed Hamed, Ramez Reda Moustafa, Hend M. El Tayebi

Frontiers in Immunology. 2023 February; 10.3389/fimmu.2023.1087595

Potential Therapeutic Effects of Morin Hydrate in Folic Acid-Induced Acute Kidney Injury

A Ahmed, D Elgamal, A Mohammad Farrag, F Ali, M Abd El-Aziz, M Abd El-Maksoud, I Ibrahim

American Journal of Clinical Pathology. 2022 November; 10.1093/ajcp/aqac126.148

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