Naresh Jha

Contact

Faculty of Medicine & Dentistry - Oncology Dept
Email
njha@ualberta.ca
Phone
(780) 432-8755
Address
Cross Cancer Institute
11560 University Avenue
Edmonton AB
T6G 1Z2

Overview

Area of Study / Keywords


About

Clinical Interest
 
Head and neck and thyroid cancers.

Research

Pioneered the “Submandibular Salivary Gland Transfer Procedure” for the prevention of XRT induced xerostomia with Dr. Hadi Seikaly.
 
A phase II study to evaluate the effects of transfer of a submandibular salivary gland to the submental region (outside of the radiation field) on xerostomia in head and neck cancer patients receiving radiation treatment. (Principal Investigator).
 
A phase II multi-center study of submandibular salivary gland transfer to the submental space prior to start of radiation treatment, for the prevention of XRT induced xerostomia in head and neck cancer patients. (Principal Investigator). RTOG – 0244.
 
A phase III randomized, multi-center Canadian study trial comparing oral pilocarpine (Salagen) vs. submandibular salivary gland transfer protocol, for the prevention of radiation (XRT) induced xerostomia in head and neck cancer patients. (Principal Investigator).
 
To study the impact of dental complications (DMFT Index, Gingival Index, Plaque Index, Streptococcus Mutans assay), secondary to XRT induced xerostomia in the two arms of the phase III randomized study comparing oral Pilocarpine vs. submandibular salivary gland transfer protocol for the prevention of XRT induced xerostomia.
 
Prevention of xerostomia using the submandibular gland transfer procedure: Impact on functional outcomes (swallowing, speech) and quality of life, after treatment for head and neck cancer.
A phase I/II feasibility/efficacy study using Intensity-Modulated Radiation Therapy (IMRT) in Head and Neck (H & N) cancer patients to permit sparing of parotid gland function.
 
Collaboration with Department of Pharmacy, University of Alberta, on “Cellular Brachytherapy project.”

Featured Publications

Joseph K., Wong J., Abraham A., Zebak J., Patel A., Jones Thachuthara A., Iqbal U., Pham T.M., Menon A., Ghosh S., Warkentin H., Walker J., Jha N., Faruqi S., Salopek T.G., Smylie M.

RADIOTHERAPY AND ONCOLOGY. 2022 January; 166 10.1016/j.radonc.2021.11.015


Alheejawi S., Berendt R., Jha N., Maity S.P., Mandal M.

Tissue and Cell. 2021 December; 73 10.1016/j.tice.2021.101659


Alheejawi S., Berendt R., Jha N., Maity S.P., Mandal M.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2021 November; 10.1109/EMBC46164.2021.9630443


An efficient CNN based algorithm for detecting melanoma cancer regions in H&E-stained images.

Annual International Conference of IEEE Engineering in Medican and Biology Society. 2021 October;


Patterns and predictors of relapse in Merkel Cell carcinoma: Results from a population based study.

ESTRO. 2021 August;


Alheejawi S., Berendt R., Jha N., Maity S.P., Mandal M.

Computerized Medical Imaging and Graphics. 2021 April; 89 10.1016/j.compmedimag.2021.101893