Paul W Armstrong
Contact
Professor, Faculty of Medicine & Dentistry - Medicine Dept
- parmstro@ualberta.ca
- Phone
- (780) 492-0591
Overview
Area of Study / Keywords
Acute Coronary Syndrome (ACS) Myocardial Infarction Myocardial Ischemia Heart Failure Drug: tenecteplase Drug: vericiguat Procedure: catheterisation Procedure: primary PCIe
About
Paul Armstrong is a Distinguished University Professor with the Department of Medicine (Cardiology) at the University of Alberta and founding Director of the Canadian VIGOUR Centre (Virtual Coordinating Centre for Global Collaborative Cardiovascular Research), a University of Alberta Research Centre devoted to enhancing cardiovascular health for current and future generations through the conduct of innovative clinical investigations and the dissemination of their learnings. He was the founding President of the Canadian Academy of Health Sciences and is a Fellow of the Royal Society of Canada. From 1993 to 1999, he served as Professor and Chair of the Department of Medicine at the University of Alberta; thereafter the department renamed its annual research award the “Paul W. Armstrong Excellence in Research Award” in recognition of his contributions.
As of August 2023 ,he has authored and co-authored over 850 peer-reviewed publications (h-index 145; i10 index 742; >190,000 citations). He has served on the editorial boards of all of the major cardiovascular journals and currently is a member of the editorial board for Circulation, European Heart Journal, JAMA Cardiology, the American Heart Journal and is a senior advisory editor for Circulation. Dr. Armstrong’s commitment to the education, training, and mentoring of healthcare professionals, research trainees, and faculty is a key signature of his career for which he has received numerous awards. In recognition of his research leadership, he received the Research Achievement Award from the Canadian Cardiovascular Society, the Award of Merit from the Heart and Stroke Foundation of Canada and the Prix Galien Canada Research Award for significant contributions to pharmaceutical research in Canada. In 2007, he received the J. Gordin Kaplan Award, for research excellence at the University of Alberta, and the Christie Award from the Canadian Association of Professors of Medicine in 2008. In 2011, he was the recipient of an Excellence in Humanism award from the University of Alberta’s Faculty of Medicine and Dentistry.
Dr. Armstrong was elevated to the rank of “University Professor” in 2006 and to “Distinguished University Professor” in 2009 at the University of Alberta. In 2014, he was awarded the University of Alberta Cup, in recognition of outstanding distinction in scholarly research, teaching, and service. He was awarded the Margolese National Heart Disorders Prize from the University of British Columbia in 2014 for outstanding contributions to the treatment, amelioration or cure of heart disorders. In 2017, Dr. Armstrong was appointed Officer of the Order of Canada, Canada’s highest civilian honour for "contributions to the advancement of cardiology, notably for his pioneering research in acute cardiac care, and for his leadership in health care institutions." In 2023, he received the Lifetime Achievement Award from the American College of Cardiology in recognition of his outstanding achievements in the field of cardiovascular disease.
Research
Dr. Armstrong is an internationally recognized expert in acute coronary disease and heart failure and has a particular interest in novel approaches to clinical trial design and interpretation. His research pursues two major lines of inquiry. The first addresses the pathophysiology of congestive heart failure and the development of novel therapeutic approaches. The second involves the pathophysiology, diagnosis, and management of acute coronary syndromes. Dr. Armstrong is widely recognised as a leader in the development of innovative national and international clinical trials. He has played a lead role in multiple large-scale international clinical trials of novel treatment strategies for cardiovascular disease, which have enhanced the worldwide care of patients. His research approach to acute myocardial infarction has been seminal in transforming prehospital care as it relates to multidisciplinary collaborative diagnosis and therapies. He played a major leadership and advisory role on key clinical trials and data safety monitoring boards that impacted the direction of cardiovascular medicine.
Featured Publications
Pieske B, Pieske-Kraigher E, Lam CSP, Melenovský V, Sliwa K, Lopatin Y, Arango JL, Bahit MC, O'Connor CM, Patel MJ, Roessig L, Morris DA, Kropf M, Westerhout CM, Zheng Y, Armstrong PW; VICTORIA Study Group
Eur J Heart Fail. 2023 July; 25 (7):1012-1021 10.1002/ejhf.2836
Vericiguat in patients with coronary artery disease and heart failure with reduced ejection fraction
Saldarriaga C., Atar D., Stebbins A., Lewis B.S., Abidin I.Z., Blaustein R.O., Butler J., Ezekowitz J.A., Hernandez A.F., Lam C.S.P., O'Connor C.M., Pieske B., Ponikowski P., Roessig L., Voors A.A., Anstrom K.J., Armstrong P.W.
EUROPEAN JOURNAL OF HEART FAILURE. 2022 May; 24 (5):782-790 10.1002/ejhf.2468
Kaul P., Klassen N., Dover D.C., Sepehrvand N., Sandhu R.K., van Diepen S., Bainey K., Sean McMurtry M., Welsh R.C., Ezekowitz J.A., Goodman S.G., Armstrong P.W., McAlister F.A.
CJC Open. 2022 February; 4 (2):180-188 10.1016/j.cjco.2021.09.017
Ezekowitz J.A., Zheng Y., Cohen-Solal A., Melenovský V., Escobedo J., Butler J., Hernandez A.F., Lam C.S.P., O'Connor C.M., Pieske B., Ponikowski P., Voors A.A., deFilippi C., Westerhout C.M., McMullan C., Roessig L., Armstrong P.W.
CIRCULATION. 2021 November; 144 (18):1489-1499 10.1161/CIRCULATIONAHA.121.056797
Armstrong P.W.
CIRCULATION. 2021 August; 144 (8):583-585 10.1161/CIRCULATIONAHA.121.055907
Voors A.A., Mulder H., Reyes E., Cowie M.R., Lassus J., Hernandez A.F., Ezekowitz J.A., Butler J., O'Connor C.M., Koglin J., Lam C.S.P., Pieske B., Roessig L., Ponikowski P., Anstrom K.J., Armstrong P.W.
EUROPEAN JOURNAL OF HEART FAILURE. 2021 August; 23 (8):1313-1321 10.1002/ejhf.2221
Lam C.S.P., Giczewska A., Sliwa K., Edelmann F., Refsgaard J., Bocchi E., Ezekowitz J.A., Hernandez A.F., O'Connor C.M., Roessig L., Patel M.J., Pieske B., Anstrom K.J., Armstrong P.W.
JAMA Cardiology. 2021 June; 6 (6):706-712 10.1001/jamacardio.2020.6455
Ponikowski P, Alemayehu W, Oto A, Bahit MC, Noori E, Patel MJ, Butler J, Ezekowitz JA, Hernandez AF, Lam CSP, O'Connor CM, Pieske B, Roessig L, Voors AA, Westerhout C, Armstrong PW; VICTORIA Study Group.
EUROPEAN JOURNAL OF HEART FAILURE. 2021 June; 10.1002/ejhf.2285
Mentz RJ, Mulder H, Mosterd A, Sweitzer NK, Senni M, Butler J, Ezekowitz JA, Lam CSP, Pieske B, Ponikowski P, Voors AA, Anstrom KJ, Armstrong PW, O'Connor CM; VICTORIA Study Group.
JOURNAL OF CARDIAC FAILURE. 2021 May; S1071-9164 (21):00206-2 10.1016/j.cardfail.2021.05.016
van Diepen S., Armstrong P.W.
EUROPEAN HEART JOURNAL. 2021 March; 42 (9):915-918 10.1093/eurheartj/ehaa1033
Voors A.A., Mulder H., Reyes E., Cowie M.R., Lassus J., Hernandez A.F., Ezekowitz J.A., Butler J., O'Connor C.M., Koglin J., Lam C.S.P., Pieske B., Roessig L., Ponikowski P., Anstrom K.J., Armstrong P.W.
EUROPEAN JOURNAL OF HEART FAILURE. 2021 January; 10.1002/ejhf.2221
Luoma L.M., Westerhout C.M., Granger C.B., Armstrong P.W.
JAMA Cardiology. 2020 November; 5 (11):1286-1297 10.1001/jamacardio.2020.2855
Ezekowitz J.A., O'Connor C.M., Troughton R.W., Alemayehu W.G., Westerhout C.M., Voors A.A., Butler J., Lam C.S.P., Ponikowski P., Emdin M., Patel M.J., Pieske B., Roessig L., Hernandez A.F., Armstrong P.W.
JACC-Heart Failure. 2020 November; 8 (11):931-939 10.1016/j.jchf.2020.08.008
Armstrong P.W., Lam C.S.P., Anstrom K.J., Ezekowitz J., Hernandez A.F., O'Connor C.M., Pieske B., Ponikowski P., Shah S.J., Solomon S.D., Voors A.A., She L., Vlajnic V., Carvalho F., Bamber L., Blaustein R.O., Roessig L., Butler J.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2020 October; 324 (15):1512-1521 10.1001/jama.2020.15922