Graham Plastow, PhD

Prof/CEO Livestock Gentec Ctr, Faculty of Agricultural, Life and Environmental Sci - Ag, Food & Nutri Sci Dept

Contact

Prof/CEO Livestock Gentec Ctr, Faculty of Agricultural, Life and Environmental Sci - Ag, Food & Nutri Sci Dept
Email
plastow@ualberta.ca
Phone
(780) 492-1496
Address
1416 College Plaza
8215 - 112 St
Edmonton AB
T6G 2C8

Overview

About

Degree

PhD, University of Leicester, UK

Job/Research Area

Animal genomics


Research

Major Responsibilities/Research Interests

Livestock Gentec was created in 2010 to continue the ABGP's research and bring the commercial benefits of genomics to the Canadian livestock industry. Livestock Gentec extends the genomics scope to other livestock species, and expands on existing technology transfer and industry collaboration efforts. Funded by Alberta Innovates BioSolutions, Gentec consists of a core group of highly qualified researchers across the University and its partners in Alberta (e.g. Alberta Agriculture) and across Canada (including Agriculture and Agri-Food Canada and the Universities of Calgary, Guelph and Saskatchewan). Partners and collaborators include livestock industry associations, government agencies and private sector companies from all over the world as well as significant international collaborations with leading Universities and Institutes.

The Gentec Executive team have extensive experience in managing large-scale multinational projects, and an excellent track record in commercializing technology. Our technology transfer professionals focus on educating industry about the benefits of the technologies we are developing. The scientific team is world-class and represents a comprehensive spread of relevant scientific interests and expertise, including genomics, genetics, microbial ecology and epigenetics, as well as statistical genetics/genomics, computing science and bioinformatics.

My main research interest is the application of genomics to increase value for all of the links within protein value chains (from the animal breeder to the consumer) with a focus on improving animal health. My main ambition is to develop the program, together with other groups in ALES and their partners, to develop new tools for application in many of the farmed animal species.

Courses

AN SC 376 - Animal Welfare

An overview of animal welfare as it relates to both food and companion animals. Discussion of the scientific and ethical components that underlie our evaluation of the quality of life that animals experience. Prerequisite: (AN SC 101 or 200) or (*3 biology and consent of instructor) and *60.

Fall Term 2020
AN SC 384 - Principles of Animal Genetics

An introduction to the basic principles of animal genetics and their practical application in selection strategies, breeding systems, and methods of improvement for domestic animals. Prerequisites: BIOL 207 and AN SC 101 or consent of instructor.

Fall Term 2020
AN SC 400 - Individual Study

Project or reading course supervised by a Faculty member, requiring preparation of a comprehensive report. Prerequisites: Third year standing or higher and consent of Department. Note: May be taken more than once if topic is different.

Fall Term 2020

Browse more courses taught by Graham Plastow

Publications

Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus PRRSV reveals pathway differences between pigs with alternate genotypes for a major host response QTL
Author(s): Schroyen, M., Eisley, C., Koltes, J.E., Fritz-Waters, E., Choi, I., Plastow, G., Guan, L., Stothard, P., Bao, H., Kommadath, A., Reecy, J.M., Lunney, J.K., Rowland, R.R.R., Dekkers, J.C.M., Tuggle, C.K.
Publication Date: 2016
Publication: BMC Genomics
Volume: 17
Page Numbers: 196

Comparative transcriptomic analysis of rectal tissue from beef steers revealed reduced host immunity in Escherichia coli O157:H7 super-shedders
Author(s): Wang, O., Liang, G., McAllister, T.A., Plastow, G., Stanford, K., Selinger, B., Guan, L.L.
Publication Date: 2016
Publication: PLoS ONE
Volume: 11
Issue: 3
Page Numbers: e0151284

Differences in Whole Blood Gene Expression Associated With Infection Time-course and Extent of Fetal Mortality in a Reproductive Model of type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection
Author(s): Wilkinson, J.M., Ladinig, A., Bao, H., Kommadath, A., Stothard, P., Lunney, J.K., Harding, J.C.S., Plastow, G.S.
Publication Date: 2016
Publication: PLoS ONE
Volume: 11
Issue: 4
Page Numbers: e0153615

Genome wide association studies (GWAS) identify QTL on SSC2 and SSC17 affecting loin peak shear force in crossbred commercial pigs
Author(s): Zhang, C., Bruce, H., Yang, T., Charagu, P., Kemp, R.A., Boddicker, N., Miar, Y., Wang, Z., Plastow, G.
Publication Date: 2016
Publication: PLoS ONE
Volume: 11
Issue: 2
Page Numbers: e0145082

Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetus
Author(s): Wilkinson, J., Bao, H., Ladinig, A., Hong, L., Stothard, P., Lunney, J., Plastow, G., Harding, J.
Publication Date: 2016
Publication: BMC Genomics
Volume: 17
Page Numbers: 383

Use of genomic tools to improve cattle health in the context of infectious diseases
Author(s): Raszek, M.M., Guan, L.L., Plastow, G.S.
Publication Date: 2016
Publication: Frontiers in Genetics
Volume: 7
Page Numbers: 30

A genome-wide association study of fetal response to type 2 porcine reproductive and respiratory syndrome virus challenge
Author(s): Yang, T., Wilkinson, J., Wang, Z., Ladinig, A., Harding, J., Plastow, G.
Publication Date: 2016
Publication: Scientific Reports
Volume: 6
Page Numbers: 20305

Accuracy of genomic predictions for feed efficiency traits of beef cattle using 50K and imputed HD genotypes
Author(s): Lu, D., Akanno, E.C., Crowley, J.J., Schenkel, F., Li, H., De Pauw, M., Moore, S.S., Wang, Z., Li, C., Stothard, P., Plastow, G., Miller, S.P., Basarab, J.A
Publication Date: 2016
Publication: J. Anim. Sci.
Volume: 94
Page Numbers: 1342-1353

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene
Author(s): Dorshorst, B., Henegar, C., Liao, X., Sällman Almén, M., Rubin, C.-J., Ito, S., Wakamatsu, K., Stothard, P., Van Doormaal, B., Plastow, G., Barsh, G.S., Andersson, L.
Publication Date: 2015
Publication: PLoS ONE
Volume: 10
Page Numbers: e0128969.

Genome-wide association for heifer reproduction and calf performance traits in beef cattle
Author(s): Akanno, E.C., Plastow, G.S., Fitzsimmons, C., Miller, S.P., Baron, V.S., Ominski, K., Basarab, J.A.
Publication Date: 2015
Publication: Genome
Volume: 12
Page Numbers: 549-557

Genome-wide association studies (GWAS) identify a QTL close to PRKAG3 affecting meat pH and colour in crossbred commercial pigs
Author(s): Zhang, Z., Wang, Z., Bruce, H., Kemp, R.A., Charagu, P., Miar, Y., Yang, T., Plastow, G.S.
Publication Date: 2015
Publication: BMC Genetics
Volume: 16
Page Numbers: 33

Genome-wide whole blood microRNAome and transcriptome analyses revealed miRNA-mRNA regulated host response to foodborne pathogen Salmonella infection in swine
Author(s): Bao, H., Kommadath, A., Liang, G., Sun, X., Arantes, A., Tuggle, C., Bearson, S., Plastow, G., Stothard, P., Guan, L.L.
Publication Date: 2015
Publication: Scientific Reports
Volume: 5
Page Numbers: 12620

Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection
Author(s): Koltes, J.E., Fritz-Waters, E., Eisley, C.J., Choi, I., Bao, H., Kommadath, A., Serão, N.V.L., Boddicker, N.J., Abrams, S.M., Schroyen, M., Loyd, H., Tuggle, C.K., Plastow, G.S., Guan, L., Stothard, P., Lunney, J.K., Liu, P., Carpenter, S., Rowland, R.R.R., Dekkers, J.C.M., Reecy, J.M.
Publication Date: 2015
Publication: BMC Genomics
Volume: 16
Page Numbers: 412

Maternal and fetal predictors of fetal viral load and death in third trimester, type 2 porcine reproductive and respiratory syndrome virus infected pregnant gilts
Author(s): Ladinig, A., Ashley, C., Detmer, S.E., Wilkinson, J.M., Lunney, J.K., Plastow, G., Harding, J.C.S.
Publication Date: 2015
Publication: Veterinary Research
Volume: 46
Page Numbers: 107

Transcriptomic and Epigenetic Profiling of the Lung of Influenza-infected Pigs: A Comparison of Different Birth Weight and Susceptibility Groups
Author(s): Wilkinson, J.M., Gunvaldsen, R.E., Detmer, S.E., Dyck, M.K., Dixon, W.T., Foxcroft, G.R., Plastow, G., Harding, J.C.S.
Publication Date: 2015
Publication: PLoS ONE
Volume: 10
Page Numbers: e0138653

Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project
Author(s): Andersson, L., Archibald, A.L., Bottema, C.D., Brauning, R., Burgess, S.C., Burt, D.W., Casas, E., Cheng, H.H., Clarke, L., Couldrey, C., Dalrymple, B.P., Elsik, C.G., Foissac, S., Giuffra, E., Groenen, M.A., Hayes, B.J., Huang, L.S., Khatib, H., Kijas, J.W., Kim, H., Lunney, J.K., McCarthy, F.M., McEwan, J.C., Moore, S., Nanduri, B., Notredame, C., Palti, Y., Plastow, G.S., Reecy, J.M., Rohrer, G.A., Sarropoulou, E., Schmidt, C.J., Silverstein, J., Tellam, R.L., Tixier-Boichard, M., Tosser-Klopp, G., Tuggle, C.K., Vilkki, J., White, S.N., Zhao, S., Zhou, H., and The FAANG Consortium
Publication Date: 2015
Publication: Genome Biology
Volume: 16
Page Numbers: 57

A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project
Author(s): Stothard, P., Liao, X., Arantes, A.S., De Pauw, M., Coros, C., Plastow, G.S., Sargolzaei, M., Crowley, J.J., Basarab, J.A., Schenkel, F., Moore, S., Miller, S.P.
Publication Date: 2015
Publication: GigaScience
Volume: 4
Page Numbers: 49

Applications of genomics to improve livestock in the developing world
Author(s): Rothschild, M.F., Plastow, G.S
Publication Date: 2014
Publication: Livestock Science
Volume: 166
Page Numbers: 76-83

Associations between single nucleotide polymorphisms in 33 candidate genes and meat quality traits in commercial pigs
Author(s): Zhang, C.Y., Wang, Z., Bruce, H.L., Janz, J., Goddard, E., Moore, S., Plastow, G.S.
Publication Date: 2014
Publication: Animal Genetics
Volume: 45
Page Numbers: 508–516

Birth Weight, Intrauterine Growth Retardation and Fetal Susceptibility to Porcine Reproductive and Respiratory Syndrome Virus
Author(s): Ladinig, A., Foxcroft, G., Ashley, C., Lunney, J.K., Plastow, G., Harding, J.C.S.
Publication Date: 2014
Publication: PLoS ONE
Volume: 9
Page Numbers: e109541

Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome
Author(s): Ladinig, A., Lunney, J.K., Souza, C.J.H., Ashley, C., Plastow, G., Harding, J.C.S.
Publication Date: 2014
Publication: Veterinary Research
Volume: 45
Page Numbers: 113

Gene co-expression network analysis identifies porcine genes associated with variation in Salmonella shedding
Author(s): ommadath, A., Bao, H., Arantes, A.S., Plastow, G.S., Tuggle, C.K., Bearson, S.M.D., Guan, L.L., Stothard, P.
Publication Date: 2014
Publication: BMC Genomics
Volume: 15
Page Numbers: 452

Genetic analysis of reproductive traits and antibody response in a PRRS outbreak herd
Author(s): Serao, N.V.L., Matika, O., Kemp, R.A., Harding, J.C.S., Bishop, S.C., Plastow, G.S., Dekkers, J.C.M.
Publication Date: 2014
Publication: J. Anim. Sci.
Volume: 92
Page Numbers: 2905-2921

Genetic and Phenotypic Parameters for Carcass and Meat Quality Traits in Commercial Crossbred Pigs
Author(s): Miar, Y., Plastow, G.S., Moore, S.S., Manafiazar, G., Charagu, P., Kemp, R.A., Van Haandel, B., Huisman, A.E., Zhang, C.Y., McKay, R.M., Bruce, H.L., Wang, Z.
Publication Date: 2014
Publication: J. Anim. Sci.
Volume: 92
Page Numbers: 2869-2884

Increasing gene discovery and coverage using RNA-seq of globin RNA reduced porcine blood samples
Author(s): Choi, I., Bao, H., Kommadath, A., Hosseini, A., Sun, X., Meng, Y., Stothard, P., Plastow, G.S., Tuggle, C.K., Reecy, J.M., Fritz-Waters, E., Abrams, S.M., Lunney, J.K., Guan, L.L.
Publication Date: 2014
Publication: BMC Genomics
Volume: 15
Page Numbers: 954

Influence of on-farm production practices on sensory and technological quality characteristics of pork loin
Author(s): Omana, D.A., Goddard, E., Plastow, G.S., Janz, J., Ma, L., Anders, S., Moore, S.S., Bruce, H.L.
Publication Date: 2014
Publication: Meat Science
Volume: 96
Page Numbers: 316-320

MicroRNA Buffering and Altered Variance of Gene Expression in Response to Salmonella Infection
Author(s): Bao, H., Kommadath, A., Plastow, G.S., Tuggle, C.K., Guan, L.L., Stothard, P.
Publication Date: 2014
Publication: PLoS ONE
Volume: 9
Page Numbers: e94352

Plasma metabolites associated with residual feed intake and other productivity performance traits in beef cattle
Author(s): Karisa, B.K, Thomson, J., Wang, Z., Li, C., Montanholi, Y., Miller, S.P., Moore, S.S., Plastow, G.S.
Publication Date: 2014
Publication: Livestock Science
Volume: 165
Page Numbers: 200–211

Reliability of molecular breeding values for Warner-Bratzler shear force and carcass traits of beef cattle – An independent validation study
Author(s): Akanno, E.C., Plastow, G., Woodward, B.W., Bauck, S., Okut, H., Wu, X.L., Sun, C., Aalhus, J.L., Moore, S.S., Miller, S.P., Wang, Z., Basarab, J.A.
Publication Date: 2014
Publication: J. Anim. Sci.
Volume: 92
Page Numbers: 2896–2904

Sequence, structural and expression divergence of duplicate genes in the bovine genome
Author(s): Liao, X., Bao, H., Meng, Y., Plastow, G., Moore, S., Stothard, P.
Publication Date: 2014
Publication: PLoS One
Volume: 9
Issue: 7
Page Numbers: e102868

Single nucleotide polymorphisms for feed efficiency and performance in crossbred beef cattle
Author(s): Abo-Ismail, M.K., Vander Voort, G., Squires, J.J., Swanson, K.C., Mandell, I.B., Liao, X., Stothard, P., Moore, S., Plastow, G., Miller, S.P.
Publication Date: 2014
Publication: BMC Genetics
Volume: 15
Page Numbers: 14

Variation in Fetal Outcome, Viral Load and ORF5 Sequence Mutations in a Large Scale Study of Phenotypic Responses to Late Gestation Exposure to Type 2 Porcine Reproductive and Respiratory Syndrome Virus
Author(s): Ladinig, A., Wilkinson, A., Ashley, C., Detmer, S.E., Lunney, J.K., Plastow, G., Harding, J.C.S.
Publication Date: 2014
Publication: Virus. PLoS ONE
Volume: 9
Page Numbers: e96104

Variation in time and magnitude of immune response and viremia in experimental challenges with Porcine circovirus 2b
Author(s): Engle, T., Jobman, E., Moural, T., McKnite, A., Bundy, J., Barnes, S., Davis, E., Galeota, J., Burkey, T., Plastow, G., Kachman, S., Ciobanu, D.
Publication Date: 2014
Publication: BMC Veterinary Research
Volume: 10
Page Numbers: 286

Candidate genes and single nucleotide polymorphisms associated with variation in residual feed intake in beef cattle
Author(s): Karisa, B.K., Thomson, J., Wang, Z., Stothard, P., Moore, S.S., Plastow, G.S.
Publication Date: 2013
Publication: J Anim Sci
Volume: 91
Issue: 8
Page Numbers: 3502-3513.

Expansion of ruminant-specific microRNAs shapes target gene expression divergence between ruminant and non-ruminant species
Author(s): Bao, H., Kommadath, A., Sun, X., Meng, Y., Arantes, A.S., Plastow, G.S., Guan, L.L,, Stothard, P.
Publication Date: 2013
Publication: BMC Genomics
Volume: 14
Page Numbers: 609

Genome-wide association analyses for growth and feed efficiency traits in beef cattle
Author(s): Lu, D., Miller, S., Sargolzaei, M., Kelly, M., Voort, G.V., Caldwell, T., Wang, Z., Plastow, G., Moore, S.
Publication Date: 2013
Publication: J Anim Sci
Volume: 91
Page Numbers: 3612-3633

Livestock and the promise of genomics
Author(s): Ludu, J. and Plastow, G
Publication Date: 2013
Publication: Genome
Volume: 56
Page Numbers: 556-566

Pig genomes reveal distinct patterns of artificial versus natural selection
Author(s): Li, M., Tian S., Jin, L., Zhou, G., Li, Y., Zhang, Y., Wang, T., Yeung, C.K.L., Chen, L., Ma, J., Zhang, J., Jiang, A., Li, J., Zhou, C., Zhang, J., Liu, Y., Sun, X., Zhao, H., Niu, Z., Lou, P., Xian, L., Shen, X., Liu, S., Zhang, S., Zhang, M., Zhu, L., Shuai S., Bai, L., Tang, G., Liu, H., Jiang, Y., Mai, M., Xiao, J., Wang, X., Zhou, Q., Wang, Z., Stothard, P., Xue, M., Gao, X., Luo, Z., Gu, Y., Zhu, H., Hu, X., Zhao, Y., Plastow, G.S., Wang, J., Jiang, Z., Li, K., Li, N., Li, X., Li, R.
Publication Date: 2013
Publication: Nature Genetics
Volume: 45
Page Numbers: 1431-1438

Whole genome sequencing of Gir cattle for identifying polymorphisms and loci under selection
Author(s): Liao, X., Peng, F., Forni, S., McLaren, D., Plastow, G., Stothard, P.
Publication Date: 2013
Publication: Genome
Volume: 56
Page Numbers: 592-598