Dr. Patricia Nadworny

Area of Study / Keywords

Nanotechnology Silver Antimicrobial Anti-inflammatory Chemical Engineering

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About

Dr. Nadworny completed her BSc in Chemical Engineering, followed by her PhD in Chemical Engineering and Biomedical Engineering, at the University of Alberta. The focus of her PhD was on the anti-inflammatory and antimicrobial activity of nanostructured silver, with initial work in the wound dressing space, followed by development of inhalable solutions for the treatment of lung diseases. She did an industrial post doctoral fellowship at Innovotech as an R&D associate developing various antimicrobial silvers from discovery through to product-readiness, after which she took on various roles in the company over 15 years, from Product Development Manager, to Quality and Safety Director/Biological Safety Officer, to Chief Scientific Officer, before joining FeynMed Solutions, where she currently is Chief Scientific Officer. She supported Innovotech's ISO 13485 certification, and then played a key role in obtaining and maintaining Innovotech's ISO 17025 certification. She was responsible for developing and maintaining all aspects of the company’s intellectual property portfolio, HR functions, and R&D, including budgeting; obtaining and managing grants; development of new biofilm test kits; development of antimicrobial and encrustation test methods for use as part of the company’s contract research testing services; and development of new antimicrobials. Her favorite projects involved developing a variety of unique antimicrobial silvers, such as high oxidation state silvers and nanostructured silver complexes, from discovery through to product-readiness, including managing collaborations with partners.  She is an inventor on 40 related patents/patent applications, and is an adjunct professor in the Department of Biomedical Engineering at the University of Alberta.

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Research

Dr. Nadworny's research focused on the development, validation, and commercialization of nanostructured materials, particularly silvers, for their anti-inflammatory and antimicrobial properties, focusing on wound care, lung (e.g., pneumonia, COPD, cystic fibrosis, ALI, ARDS, TENs, septic shock), ocular (e.g., various forms of conjunctivitis), and genitourinary (e.g., urinary tract infections, including catheter-associated infections, overactive bladder, painful bladder syndrome/interstitial cystitis, acute insults associated with the progression of radiation cystitis) applications.  She is also interested in treatments for prevention of post-surgical abdominal adhesions and surgical site infections.

Mauri Erickson, Tyler J. Boone, Patricia L. Nadworny

Viruses. 2024 June; 10.3390/v16060959

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Patricia L. Nadworny, William L. Hickerson, Holly Denise Holley-Harrison, David C. Bloom, Tristan R. Grams, Terri G. Edwards, Gregory S. Schultz, Robert E. Burrell

Nanomedicine: Nanotechnology, Biology and Medicine. 2023 February; 10.1016/j.nano.2023.102654

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Amin Omar, J. Wright, Gregory Schultz, Robert Burrell, Patricia Nadworny

Microorganisms. 2017 March; 10.3390/microorganisms5010009

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Amin Omar, Patricia Nadworny

Advanced Drug Delivery Reviews. 2017 March; 10.1016/j.addr.2016.09.003

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Vanessa Incani, Amin Omar, Graeme Prosperi-Porta, Patricia Nadworny

International Journal of Antimicrobial Agents. 2015 June; 10.1016/j.ijantimicag.2014.09.008

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Patricia L Nadworny, JianFei Wang, Edward E Tredget, Robert E Burrell

Journal of Inflammation. 2010 December; 10.1186/1476-9255-7-13

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Marion H Cavanagh, Robert E Burrell, Patricia L Nadworny

International Wound Journal. 2010 October; 10.1111/j.1742-481x.2010.00705.x

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Patricia L. Nadworny, Breanne K. Landry, JianFei Wang, Edward E. Tredget, Robert E. Burrell

Wound Repair and Regeneration. 2010 March; 10.1111/j.1524-475x.2010.00579.x

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Breanne K. Landry, Patricia L. Nadworny, Oladipo E. Omotoso, Yadollah Maham, Jessica C. Burrell, Robert E. Burrell

Biomaterials. 2009 December; 10.1016/j.biomaterials.2009.09.003

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P.L. Taylor, A.L. Ussher, R.E. Burrell

Biomaterials. 2005 December; 10.1016/j.biomaterials.2005.05.040

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P.L. Taylor, O. Omotoso, J.B. Wiskel, D. Mitlin, R.E. Burrell

Biomaterials. 2005 December; 10.1016/j.biomaterials.2005.05.041

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