Lynne Postovit
Contact
Faculty of Medicine & Dentistry - Oncology Dept
- postovit@ualberta.ca
- Phone
- (780) 492-6342
Overview
Area of Study / Keywords
About
Dr. Postovit is the Sawin-Baldwin Chair in Ovarian Cancer and an Associate Adjunct Professor in the Department of Obstetrics & Gynecology. Her Primary Appointment is Associate Professor in the Department of Oncology, University of Alberta.Research
Bidirectional communication between cells and their microenvironment is a hallmark of both cancer progression and embryological development. Indeed, in all physiological instances, cells do not survive autonomously, but rather rely on extracellular cues to direct functions as diverse as proliferation, apoptosis, invasion and differentiation. The past decade has seen an explosion of research on cells with the capacity to differentiate in response to specific microenvironmental cues. During embryogenesis, these "stem cells" are the source of all cell lineages and in
- Role of oxygen as an epigenetic regulator of tumour progression and metastasis
- Role of the extracellular matrix proteins in the regulation of stem cells and cancers
- Function and regulation of the embryonic protein Nodal in cancer and stem cells
- Microenvironmental regulation of cancer progression at the cancer-stroma interface.
- Microenvironmental regulation of placental development at the feto-maternal interface
- Identifying biomarkers that can predict ovarian cancer
- Identifying targets for the treatment and prevention of ovarian cancer metastasis
Translational Research Team Focussed of Cancers Affecting Women
One of our major goals is to see the work that we do in the lab translate into new treatments or early detection methods for cancer patients: We want to translate our scientific results into clinical practice. To do this, we work in teams. One newly formed team at the University of Alberta is the Ovarian Cancer Research Team. Faculty members in this team include