Peter Senior
Contact
Director, Faculty of Medicine & Dentistry - Alberta Diabetes Research Institute
- psenior@ualberta.ca
- Address
-
1.005 Li Ka Shing Centre For Research
8602 112 Street NWEdmonton ABT6G 2E1
Overview
Area of Study / Keywords
Coronary artery disease PET-CT Diabetes Insulin analog CSII cardiovascular disease primary prevention anti-platelet islet transplant incretin nephropathy proteinuria PDE-5 inhibitor diabetes gastroparesis motilin agonist type 1 diabetes immunotherapy clinical trial intervention
About
Charles A Allard Chair in Diabetes Research
Director, Alberta Diabetes Institute
Professor, Division of Endocrinology & Metabolism
Degrees
- BMedSci (Hons) University of Newcastle Upon Tyne 1992
- MBBS (Hons) University of Newcastle Upon Tyne 1993
- PhD University of Newcastle Upon Tyne 2002
Clinical Expertise
- Type 1 Diabetes
- Complex Diabetes
- Clinical Islet Transplantation
- Insulin Pump Therapy
- General Endocrinology
- Diabetic Nephropathy
Clinical Interests
- Type 1 diabetes
- Hypoglycemia
- Insulin Pump Therapy
- Automated insulin delivery
- Diabetic Nephropathy
- Atypical types of diabetes
- Monogenic
- Pancreatogenic
Research
Research
Clinical Islet Transplantation
- refining and enhancing the edmonton Protocol
- describing clinical and metabolic outcomes after islet transplant
- developing clinical tools to track islet function over time
- testing new sites for islet transplantation
- phase 1/2 trials of stem cell derived beta cells
Diabetic Nephropathy
- health services research examining the effectiveness of community diabetic nephropathy prevention clinics
- Preventing Early Renal Loss in Diabetes (www.perl-study.org)
Clinical Trials
- interventions for new onset type 1 diabetes
- phase 2 and 3 clinical trials of new agents to treat diabetes or its complications
Autoimmune Complications of Lymphodepleting Therapies in MS
Teaching
Teaching
Clinical Teaching
much of my teaching is done in clinics and the hospital
Classroom Teaching
DMED 513, PMCOL 402/502, MED 608
Continuing Medical Education
regularly deliver CME locally, nationally, and internationally
Featured Publications
Anna Lam, Richard Oram, Shareen Forbes, Tolu Olateju, Sharleen Imes, Andrew J Malcolm, AM James Shapiro, Peter A Senior
TRANSPLANT INTERNATIONAL. 2022 July; 35 10.3389/ti.2022.10335
Amy E.Morrison, Peter A.Senior, TaniaBubela, KateFarnsworth, HollyWitteman, AnnaLam
Canadian Journal of Diabetes. 2022 June; https://doi.org/10.1016/j.jcjd.2022.06.003
Kevin Verhoeff, Braulio A Marfil-Garza, Gurpal Sandha, David Cooper, Khaled Dajani, David L Bigam, Blaire Anderson, Tatsuya Kin, Anna Lam, Doug O’Gorman, Peter A Senior, Camillo Ricordi, AM James Shapiro
TRANSPLANTATION. 2022 June; DOI: 10.1097/TP.0000000000004180
KellyPicard, Peter A.Senior, AshleyWilmott, KailashJindal, CarolineRichard, Diana R.Mager
CANADIAN JOURNAL OF DIETETIC PRACTICE AND RESEARCH. 2022 May; https://doi.org/10.3148/cjdpr-2022-009
Marfil-Garza B.A., Imes S., Verhoeff K., Hefler J., Lam A., Dajani K., Anderson B., O'Gorman D., Kin T., Bigam D., Senior P.A., Shapiro A.M.J.
Lancet Diabetes & Endocrinology. 2022 May; 10 (7):519-532 10.1016/S2213-8587(22)00114-0
Lane W., Favaro E., Jódar E., Kelkar P., Oviedo A., Sivarathinasami R., Senior P.A., Sesti G., Franek E.
Diabetes Therapy. 2022 April; 13 (4):761-774 10.1007/s13300-022-01213-3
IMPROVED GLYCEMIA AND QUALITY OF LIFE AMONG LOOP USERS-A RETROSPECTIVE ANALYSIS OF REAL-WORLD DATA FROM A SINGLE CENTRE.
DIABETES TECHNOLOGY & THERAPEUTICS. 2022 April;
Bonhoure A., Potter K.J., Reynaud Q., Boudreau V., Senior P.A., Tremblay F., Lavoie A., Durieu I., Rabasa-Lhoret R.
Canadian Journal of Diabetes. 2022 April; 46 (3):294-301.e2 10.1016/j.jcjd.2021.11.004
Severity of proteinuria is associated with incident fragility fractures in patients with chronic kidney disease independent of estimated glomerular filtration rate.
JOURNAL OF BONE AND MINERAL RESEARCH. 2022 April;
WHO IS USING DO-IT-YOURSELF ARTIFICIAL PANCREAS SYSTEMS AND WHY
DIABETES TECHNOLOGY & THERAPEUTICS. 2022 April;
Yewande Kofoworola Ogundejia, Amity Quinn, Meaghan Lunney, Christy Chong, Derek Chew, Shelley Duggan, Alun Edwards, Peter Senior, Glen Sumner, Jennifer Williams, Kelly Zarnke, Braden Manns
The American Journal of Accountable Care. 2022 March; 10 (1):8-18 https://doi.org/10.37765/ajac.2022.88847
Peter Senior, Martin Drage, Anneliese Flatt, Chris Callaghan
Oxford Textbook of Endocrinology and Diabetes. 2022 March; (3rd edition) 10.1093/med/9780198870197.003.0258
Mathe N., Ryan A., Cook A., Sargious P., Senior P., Johnson J.A., Yeung R.O.
Canadian Journal of Diabetes. 2022 January; 10.1016/j.jcjd.2021.12.001
Marasinghe D.H., Butalia S., Garies S., Drummond N., Kim J.W., Senior P.A.
Canadian Journal of Diabetes. 2022 January; 10.1016/j.jcjd.2022.02.002
A Hemoglobin A1c Greater Than 6.0% is Associated With Lower Lung Function in Adults at Risk for Cystic Fibrosis-Related Diabetes
Canadian Journal of Diabetes. 2021 December;
Starting the Process of Quality Improvement in Edmonton’s Tertiary Diabetes Clinics: Getting Our Data Ducks in a Row
Canadian Journal of Diabetes. 2021 December;
Prevalence of Post-Glucose Challenge Hypoglycemia in Adult Patients with Cystic Fibrosis and Relevance to the Risk of Cystic Fibrosis-Related Diabetes
Canadian Journal of Diabetes. 2021 December;
Transplantation. 2021 December; 10.1097/01.tp.0000804504.96321.95
Mind the Gap: Low Use of Guideline Recommended Cardiorenal Protective Antihyperglycemics in Primary Care
Canadian Journal of Diabetes. 2021 December;
Marginal Association of Fasting Blood Glucose With the Risk of Cystic Fibrosis Related Diabetes
Canadian Journal of Diabetes. 2021 December;
Insulinogenic Index and Early Phase Insulin Secretion Predict Increased Risk of Worsening Glucose Tolerance and of Cystic Fibrosis-Related Diabetes
Canadian Journal of Diabetes. 2021 December;
Effect of a Resistance Exercise Intervention on Frailty Outcomes in Adults With Diabetes Mellitus
Canadian Journal of Diabetes. 2021 December;
Connect1d Canada Validation Study in Patient-Driven Design to Accelerate Research in Type 1 Diabetes
Canadian Journal of Diabetes. 2021 December;
Characterization of Intermittently Scanned Glucose Monitoring Profiles in Patients at Risk for Cystic Fibrosis-Related Diabetes
Canadian Journal of Diabetes. 2021 December;
Syron L., Cheng A.Y.Y., Senior P.
Canadian Journal of Diabetes. 2021 December; 45 (8):695-696 10.1016/j.jcjd.2021.10.009
Transplantation. 2021 December; 10.1097/01.tp.0000804384.59881.c9
Senior P.A.
ATHEROSCLEROSIS. 2021 October; 335 10.1016/j.atherosclerosis.2021.09.001
Potter K.J., Reynaud Q., Boudreau V., Racine F., Tremblay F., Lavoie A., Carricart M., Mailhot G., Durieu I., Senior P.A., Rabasa-Lhoret R.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021 October; 106 (10):E3901-E3910 10.1210/clinem/dgab384
Cheng A.Y.Y., Feig D.S., Ho J., Siemens R., Bajaj H., Gilbert J., Houlden R., Kim J., Mackay D., Rabi D.M., Sherifali D. Senior P.
Canadian Journal of Diabetes. 2021 October; 45 (7):580-587 10.1016/j.jcjd.2021.07.003
Potter K.J., Boudreau V., Shohoudi A., Mailhot M., Tremblay F., Lavoie A., Carricart M., Senior P.A., Rabasa-Lhoret R.
Journal of Cystic Fibrosis. 2021 September; 20 (5):803-809 10.1016/j.jcf.2020.11.022
Ogundeji Y.K., Quinn A., Lunney M., Chong C., Chew D., Hopkin G., Senior P., Sumner G., Williams J., Manns B.
Healthcare Policy. 2021 August; 17 (1):58-72 10.12927/HCPOL.2021.26577
Diabetes. 2021 June; 10.2337/db21-731-P
Picard K., Senior P.A., Adame Perez S., Jindal K., Richard C., Mager D.R.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2021 May; 31 (5):1445-1453 10.1016/j.numecd.2021.02.002
Outcomes in Alemtuzumab-Treated Patients With Thyroid Adverse Events: 6-Year Pooled CARE-MS Data
Neurology Apr 2021, 96 (15 Supplement) 1509. 2021 April;
von Herrath M., Bain S.C., Bode B., Clausen J.O., Coppieters K., Gaysina L., Gumprecht J., Hansen T.K., Mathieu C., Morales C., Mosenzon O., Segel S., Tsoukas G., Pieber T.R., Ludvik B., Prager R., Paulweber B., Ebenbichler C.F., Keymeulen B., De Block C., Grossman L., Houlden R., Perron P., Ransom T., Senior P., Weisnagel S.J., Woo V., Dumas R., Thompson D., Vilsbøll T., Gram J., Juhl C.B., Hukkanen J., Lahtela J., Niskanen L., O'Shea D., O'Brien T., Sreenan S., Wainstein J., Phillip M., Knobler H., Dotta F., Piatti P.M., Roberto T., Gnasso A., Gulseth H., Cooper J., Pankowska E., Lukaszewicz M., Wolnik B., Manita I., Marques O., Roque C., Príncipe R.M., Neves C., Heitor S., Ruyatkina L., Dvoryashina I., Vagapova G., Belousova L., Sergeeva-Kondrachenko M., Peskov A., Frolova E., Golovach A., Kunitsyna M., Krasnopeeva (Kabachkova) N., Ipatko I., De la Cuesta C., Tinahones F.J., Rigla M., Merino J.F., Gómez L.A., Fernández M., Simó R., Rydén M., Jendle J., Filipsson K., Eliasson B., Mankovsky B., Lymar I., Sokolova L., Myshanych G., Zlova T., Vlasenko M., Kuskalo P., Courtney H., Dayan C., English P., Heller S., Johnson A.B., Nair S., Leslie R.D., Narendran P., Oliver N., Ramtoola S., Shaw J., Viljoen A., Al-Karadsheh A., Dostou J.M., Gangi S., Gottlieb P., Jerkins T., Magnotti M., Marks J., Nakhle S., Bonabi G., Myers L., Pratley R., Hagopian W., Pettus J., von Scholten B.J., Wesley J.D., Kreiner F.F.
Lancet Diabetes & Endocrinology. 2021 April; 9 (4):212-224 10.1016/S2213-8587(21)00019-X
CONNECT1D-A NATIONAL, DIGITAL-FIRST, T1D REGISTRY TO ACCELERATE PATIENT-ORIENTED RESEARCH, POLICY, AND CLINICAL CARE.
DIABETES TECHNOLOGY & THERAPEUTICS. 2021 April;
Ogundeji Y.K., Quinn A., Lunney M., Chong C., Chew D., Danso G., Duggan S., Edwards A., Hopkin G., Senior P., Sumner G., Williams J., Manns B.
HEALTH POLICY. 2021 April; 125 (4):442-449 10.1016/j.healthpol.2020.12.014
Outcomes in Alemtuzumab-Treated Patients With Thyroid Adverse Events: 6-Year Pooled CARE-MS Data
Neurology. 2021 April;
Markmann J.F., Rickels M.R., Eggerman T.L., Bridges N.D., Lafontant D.E., Qidwai J., Foster E., Clarke W.R., Kamoun M., Alejandro R., Bellin M.D., Chaloner K., Czarniecki C.W., Goldstein J.S., Hering B.J., Hunsicker L.G., Kaufman D.B., Korsgren O., Larsen C.P., Luo X., Naji A., Oberholzer J., Posselt A.M., Ricordi C., Senior P.A., Shapiro A.M.J., Stock P.G., Turgeon N.A.
AMERICAN JOURNAL OF TRANSPLANTATION. 2021 April; 21 (4):1477-1492 10.1111/ajt.16174
Haddadi D., Rosolowsky E., Pacaud D., McKeen J., Young K., Madrick B., Domaschuk L., Sargious P., Conroy S., Senior P.A.
Canadian Journal of Diabetes. 2021 April; 45 (3):228-235.e4 10.1016/j.jcjd.2020.08.097
Outcomes in alemtuzumab-treated patients with thyroid adverse events: 6-year pooled care-ms data
MULTIPLE SCLEROSIS JOURNAL 26 (3_ SUPPL), 179-180. 2021 February;
Bajaj H.S., Bergenstal R.M., Christoffersen A., Davies M.J., Gowda A., Isendahl J., Lingvay I., Senior P.A., Silver R.J., Trevisan R., Rosenstock J.
DIABETES CARE. 2021 January; 44 (7):1586-1594 10.2337/dc20-2877
Open Forum Infect Dis. 2020 Oct; 7(Suppl 1): S576.. 2020 December; 10.1093/ofid/ofaa439.1279
Rosenstock J., Bajaj H.S., Jane� A., Silver R., Begtrup K., Hansen M.V., Jia T., Goldenberg R.
NEW ENGLAND JOURNAL OF MEDICINE. 2020 November; 383 (22):2107-2116 10.1056/NEJMoa2022474
Senior P., Lam A., Farnsworth K., Perkins B., Rabasa-Lhoret R.
Current Diabetes Reports. 2020 October; 20 (10):52 10.1007/s11892-020-01339-3
Infectious Complications after Pancreatic Islet Transplantation
Open Forum Infectious Diseases. 2020 October;
Lipscombe L., Butalia S., Dasgupta K., Eurich D.T., MacCallum L., Shah B.R., Simpson S., Senior P.A.
Canadian Journal of Diabetes. 2020 October; 44 (7):575-591 10.1016/j.jcjd.2020.08.001
Senior P.A., Houlden R.L., Kim J., Mackay D., Nagpal S., Rabi D., Sherifali D., Bajaj H.S.
Canadian Journal of Diabetes. 2020 October; 44 (7):592-596 10.1016/j.jcjd.2020.08.002
Residents’ Perspectives on Management of Diabetic Ketoacidosis in a Large Teaching Hospital
Can J Diabetes. 2020 October;
Canadian Journal of Diabetes VOLUME 44, ISSUE 7, SUPPLEMENT , S22-S23, . 2020 October; https://doi.org/10.1016/j.jcjd.2020.08.058
Building a clinical trial simulation tool for disease modifying therapies in type 1 diabetes (TOMI-T1D)
Diabetologia. 2020 September;
Building a clinical trial simulation tool for disease modifying therapies in type 1 diabetes (TOMI-T1D)
DIABETOLOGIA 63 (SUPPL 1), S160-S161. 2020 September;
Colomba J., Rabasa-Lhoret R., Bonhoure A., Bergeron C., Boudreau V., Tremblay F., Senior P., Potter K.
Journal of Cystic Fibrosis. 2020 September; 19 (5):704-711 10.1016/j.jcf.2020.04.004
Efficacy and safety of fast-acting insulin aspart in adults with type 2 diabetes with different insulin requirements
Diabetologia. 2020 September;
Efficacy and safety of fast-acting insulin aspart in adults with type 2 diabetes with different insulin requirements
DIABETOLOGIA 63 (SUPPL 1), S330-S330. 2020 September;