Rony Pain

Grad Research Asst Fellowship, Faculty of Medicine & Dentistry - Cell Biology Dept

Contact Publications

Contact

Grad Research Asst Fellowship, Faculty of Medicine & Dentistry - Cell Biology Dept

Email: rony@ualberta.ca

Featured Publications

Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signaling and Oxidative Phosphorylation, Killing Acute Myeloid Leukemia Cells

Jay M. Gamma, Qiang Liu, Erwan Beauchamp, Aishwarya Iyer, Megan C. Yap, Zoulika Zak, Cassidy Ekstrom, Rony Pain, Morris A. Kostiuk, John R. Mackey, Joseph Brandwein, Jean C.Y. Wang, Luc G. Berthiaume

Molecular Cancer Therapeutics. 2025 January; 10.1158/1535-7163.MCT-24-0307

Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition

Erwan Beauchamp, Jay M. Gamma, Christopher R. Cromwell, Eman W. Moussa, Rony Pain, Morris A. Kostiuk, Claudia Acevedo-Morantes, Aishwarya Iyer, Megan Yap, Krista M. Vincent, Lynne M. Postovit, Olivier Julien, Basil P. Hubbard, John R. Mackey, Luc Berthiaume

Journal of Translational Medicine. 2024 May; 10.1186/s12967-024-05150-6

Abstract CT194: N-myristoylation inhibitor zelenirstat: New mechanistic insights and efficacy signals from a first in human phase I study

Luc Gerard Berthiaume, Erwan Beauchamp, Jay Gamma, Rony Pain, Morris A. Kostiuk, Christopher R. Cromwell, Eman W. Moussa, Olivier Julien, Basil P. Hubbard, John Kuruvilla, Laurie H. Sehn, Jennifer Spratlin, Rahima Jamal, Randeep Sangha, John R. Mackey

Cancer Research. 2024 April; 10.1158/1538-7445.am2024-ct194

Abstract 1662: Understanding the sensitivity of cancer cells to myristoylation inhibitors for oncology applications

Erwan Beauchamp, Chistopher Cromwell, Eman Moussa, Aishwarya Iyer, Megan Yap, Rony Pain, Jay Gamma, Olivier Julien, Basil Hubbard, Luc Berthiaume

Cancer Research. 2023 April; 10.1158/1538-7445.am2023-1662

Abstract 3620: N-myristoylation inhibition reduces angiogenesis and cancer cell migration

Rony Pain, Erwan Beauchamp, Katia Carmine-Simmen, Jay Gamma, Rebecca Reif, Abul Azad, Allan Murray, John Lewis, Luc Berthiaume

Cancer Research. 2023 April; 10.1158/1538-7445.am2023-3620

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