Drosophila development cell cycle regulation
Although now formally retired, I still maintain an active interest in scientific research. See my CV and ORCID link (below) for more information.
Conserved regulatory mechanisms called cell cycle checkpoints are used to spatially and temporally coordinate cell proliferation with distinct aspects of development. My research concerns the mechanisms that are used to inhibit the activity of Cdk1, a cyclin-dependent kinase that coordinates mitosis in all eukaryotic cells. Cell cycle regulation is very dynamic during animal development and we have made mutants and transgenic strains to study these processes at different stages of Drosophila development. See my CV and ORCID link (below) for more information.