Tom Hobman

Area of Study / Keywords

---

About

Canada Research Chair in RNA virus host interactions

---

Research

1. Investigating how pathogenic viruses (Zika virus, West Nile virus, Dengue virus) causes disease.
   
2. Novel diagnostics for Dengue virus and Zika virus.
   
3. Identification of indirect-acting antiviral compounds.
   
4. Mechanisms by which HIV causes neurological disease (in collaboration with Dr. Chris Power)
   
5. Role of the master gene regulator Argonatue 2 in breast cancer.
   

CELL 300 - Advanced Cell Biology I

Advanced course studying various topics in modern molecular cell biology emphasizing the design of experiments, the interpretation of their results and the extrapolation of their findings. Examines aspects of eukaryotic cell structure and function. Includes, but not restricted to, areas such as protein targeting, organelle biogenesis, intracellular signaling, pathogen-cell interactions and cell-cell interactions. Makes extensive use of scientific literature to illustrate important concepts. Prerequisites: BIOL 201 or CELL 201 and BIOCH 200.

---

CELL 398 - Research Project

Directed research carried out in a laboratory of a member participating in the Cell Biology Program. Credit may be obtained for this course only once. Successful completion requires laboratory skills training and a written report on the research project. Normally for students in their third year of study. Pre- or co-requisite: any 300-level Science course, CELL 300 recommended, and the consent of the course coordinator.

---

CELL 498 - Research Project

Directed research carried out in a laboratory of an assigned member participating in the Cell Biology Program. Credit may be obtained for this course more than once. Successful completion requires application of laboratory skills and a written report on the research project. Prerequisites: A 300-level CELL, Biological Sciences, or Biochemistry course and the consent of the course coordinator.

---

Browse more courses taught by Tom Hobman

Tom C. Hobman

Fields Virology (7th Edition). 2022 August; 1 Not available yet.

---

Airo A.M., Felix-Lopez A., Mancinelli V., Evseev D., Lopez-Orozco J., Shire K., Paszkowski P., Frappier L., Magor K.E., Hobman T.C.

Viruses-Basel. 2022 May; 14 (5) 10.3390/v14050968

---

Nguyen L., McCord K.A., Bui D.T., Bouwman K.M., Kitova E.N., Elaish M., Kumawat D., Daskhan G.C., Tomris I., Han L., Chopra P., Yang T.J., Willows S.D., Mason A.L., Mahal L.K., Lowary T.L., West L.J., Hsu S.T.D., Hobman T., Tompkins S.M., Boons G.J., de Vries R.P., Macauley M.S., Klassen J.S.

Nature Chemical Biology. 2022 January; 18 (1):81-90 10.1038/s41589-021-00924-1

---

Ishida R., Cole J., Lopez-Orozco J., Fayad N., Felix-Lopez A., Elaish M., Luo S.Y., Julien O., Kumar A., Hobman T.C.

Cells. 2021 December; 10 (12) 10.3390/cells10123510

---

Doan M.A.L., Roczkowsky A., Smith M., Blevins G., van Landeghem F.K.H., Gelman B.B., Branton W.G., Stapleton J.T., Hobman T.C., Power C.

JOURNAL OF VIROLOGY. 2021 September; 95 (23) 10.1128/JVI.01074-21

---

Kumar A., Ishid R., Strilets T., Cole J., Lopez-Orozco J., Fayad N., Felix-Lopez A., Elaish M., Evseev D., Magor K.E., Mahal L.K., Nagata L.P., Evans D.H., Hobman T.C.

JOURNAL OF VIROLOGY. 2021 June; 95 (13) 10.1128/JVI.00266-21

---

Limonta D., Dyna-Dagman L., Branton W., Mancinelli V., Makio T., Wozniak R.W., Power C., Hobman T.C.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2021 May; 65 (8) 10.1128/AAC.00491-21

---

Knoblach B., Ishida R., Hobman T.C., Rachubinski R.A.

MOLECULAR BIOLOGY OF THE CELL. 2021 May; 32 (14):1273-1282 10.1091/mbc.E21-02-0074

---

Zhang K., Miorin L., Makio T., Dehghan I., Gao S., Xie Y., Zhong H., Esparza M., Kehrer T., Kumar A., Hobman T.C., Ptak C., Gao B., Minna J.D., Chen Z., García-Sastre A., Ren Y., Wozniak R.W., Fontoura B.M.A.

Science Advances. 2021 February; 7 (6) 10.1126/sciadv.abe7386

---

Bernard I., Limonta D., Mahal L.K., Hobman T.C.

Viruses-Basel. 2020 December; 13 (1) 10.3390/v13010029

---

Limonta D., Hobman T.C.

Cells. 2020 November; 9 (11) 10.3390/cells9112463

---

Heindel D.W., Koppolu S., Zhang Y., Kasper B., Meche L., Vaiana C.A., Bissel S.J., Carter C.E., Kelvin A.A., Elaish M., Lopez-Orozco J., Zhang B., Zhou B., Chou T.W., Lashua L., Hobman T.C., Ross T.M., Ghedin E., Mahal L.K.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES. 2020 October; 117 (43):26926-26935 10.1073/pnas.2008203117

---

Glasgow A., Glasgow J., Limonta D., Solomon P., Lui I., Zhang Y., Nix M.A., Rettko N.J., Zha S., Yamin R., Kao K., Rosenberg O.S., Ravetch J.V., Wiita A.P., Leung K.K., Lim S.A., Zhou X.X., Hobman T.C., Kortemme T., Wells J.A.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020 October; 117 (45):28046-28055 10.1073/pnas.2016093117