Walter Dixon

Interim Vice-President (Research and Innovation), Vice-President Research Innovation

Contact

Interim Vice-President (Research and Innovation), Vice-President Research Innovation
Email
walter.dixon@ualberta.ca
Phone
(780) 492-5353
Address
2-51 South Academic Building
11328 - 89 Ave NW
Edmonton AB
T6G 2J7

Overview

About

Degree

PhD, University of Cambridge

Job/Research Area  

Molecular Biology, and Member of AVRI Council


Research

Major Responsibilities/Research Interests 

Research interests focus on gene expression as it relates to several fundamental cell biological processes including cell adhesion, and protein metabolism and secretion. In particular, current research involves the study of a family of four-pass membrane proteins implicated in a variety of cellular processes including adhesion and motility, platelet activation, growth factor signalling and cell proliferation. Members of this protein family are being studied in several normal and transformed eukaryotic cell systems. These studies utilize many recently developed techniques in protein biochemistry and molecular biology including cDNA cloning and expression, antibody screening of cDNA libraries, polymerase chain reaction (PCR) analysis and DNA sequencing. An understanding of the critical factors regulating these essential biological processes will have direct application to a variety of important issues in animal science including fertilization, embryo implantation and development, parasite infection and lactation. 

Publications

Biological markers of boar fertility
Author(s): Dyck, M.K., Foxcroft, G.R., Novak, S., Ruiz-Sanchez, A., Patterson, J. and W.T. Dixon
Publication Date: 2011
Publication: Reprod. Domest. Anim.
Volume: 46
Issue: 2
Page Numbers: 55-58

Lysine alpha-ketoglutarate reductase, but not saccharopine dehydrogenase, is subject to substrate inhibition in pig liver
Author(s): Pink, D.B., Gatrell, S.K., Elango, R., Turchinsky, J., Kiess, A.S. Blemings, K.P., W.T. Dixon, and Ball, R.O.
Publication Date: 2011
Publication: Nutr. Res.
Volume: 31
Page Numbers: 544-554

Nitric oxide synthase inhibition delays low-frequency stimulation-induced satellite cell activation in rat fast-twitch muscle
Author(s): Martins, K.J., Maclean, I., Murdoch, G.K., W.T. Dixon, and Putman, C.T.
Publication Date: 2011
Publication: Appl. Physiol. Nutr. Metab.
Volume: 36
Issue: 6
Page Numbers: 996-1000

Restricted feed intake in lactating primiparous sows. II. Effects on subsequent litter sex ratio and embryonic gene expression
Author(s): Oliver, G., Novak, S., Patterson, J.L., Pasternak, J.A., Paradis, F., Norrby, M., Oxtoby, K., Dyck, M.K., W.T. Dixon and Foxcroft, G.R.
Publication Date: 2011
Publication: Reprod. Fertil. Develop.
Volume: 23
Page Numbers: 899-911

Cell adhesion-mediated transformation of a human SCLC cell line is associated with the development of a normal phenotype
Author(s): Gilchrist, A.J., R. Meuser, J. Turchinsky, A.R.E. Shaw, M. Pasdar, and W.T. Dixon
Publication Date: 2002
Publication: Exp. Cell Res.
Volume: 276
Page Numbers: 63-78

FEMS
Author(s): Alexander, T.W., R. Sharma, E.K. Okine, W.T. Dixon, R.J. Forster, K. Stanford, and T.A. McAllister
Publication Date: 2002
Publication: Microbiol. Lett. 10
Volume: 214
Issue: 2
Page Numbers: 263-269

Proteoglycans (Glycosaminoglycans/Mucopolysaccharides)
Author(s): Nakano, T., W.T. Dixon, and L. Ozimek
Publication Date: 2002
Publication: In: Polysaccharides II. Polysaccharides from Eukaryotes. Biopolymers
Volume: 6
Issue: 16
Page Numbers: 574-604

Regulation of IGF-1 and porcine oviductal protein (pOSP) secretion into the pig oviduct in the peri-ovulatory period, and effects of previous nutrition
Author(s): Novak, S, B.K., F.R. Treacy, C.L. Almeida, J. Mao, W.C. Buhi, W.T. Dixon, and G.R. Foxcroft
Publication Date: 2002
Publication: Reprod. Nutr. Dev.
Volume: 42
Page Numbers: 1-18

Short chain fatty acids and total parenteral nutrition affect intestinal gene expression
Author(s): Drozdowski, L.A., W.T. Dixon, A.B.R. Thomson, and M.I. McBurney
Publication Date: 2002
Publication: J. of Parenteral and Enteral Nutrition
Volume: 26
Page Numbers: 145-150

A murine monoclonal antibody, MoAb HMSA-5, against a melanosomal component highly expressed in early melanosome developmental stages, and common to normal and neoplastic melanocytes
Author(s): Der, J.E., W.T. Dixon, and K. Jimbow
Publication Date: 1993
Publication: Brit. J. Cancer
Volume: 67
Page Numbers: 47-57

The ME491 melanoma-associated glycoprotein family. Antigenic identity of the ME491, NKI/C-3, NGA and CD63 proteins
Author(s): Demetrick, D.J., D. Herlyn, M. Tretiak, D. Creasy, H. Clevers, C.J.G.M. Vennegoor, W.T. Dixon, and L.M. Jerry
Publication Date: 1992
Publication: J. Natl. Cancer Institute
Volume: 84
Page Numbers: 422-429

Biosynthesis, glycosylation and intracellular processing of the neuroglandular antigen, a human melanoma-associated antigen
Author(s): W.T. Dixon, D.J. Demetrick, K. Ohyama, L.K.J. Sikora, and L.M. Jerry
Publication Date: 1990
Publication: Cancer Research
Volume: 50
Page Numbers: 4557-4565