Prof. Mark Haykowsky

Professor, Faculty of Nursing

Research Chair in Aging and Quality of Life, Faculty of Nursing

Pronouns: "he, him, his"

Curriculum Vitæ

Contact Overview Publications

Contact

Professor, Faculty of Nursing

Email: mhaykows@ualberta.ca

Research Chair in Aging and Quality of Life, Faculty of Nursing

Email
Address: 3-045 Dianne and Irving Kipnes Health Research Academy
11405 87 Ave NW

Edmonton AB

T6G 1C9

Overview

Area of Study / Keywords

Aging; Heart Failure; CardiooOncology; Oxygen Transport & Utilization; Sports Cardiology

Teaching

Featured Publications

Impaired Peripheral Oxygen Diffusion is the Primary Determinant of Exercise Intolerance in High-risk Older Breast Cancer Survivors

Mark J. Haykowsky, Nathan R. Weeldreyer, André La Gerche, Satyam Sarma, Stephen J. Foulkes

American Journal of Physiology-Heart and Circulatory Physiology. 2026 June; 10.1152/ajpheart.00324.2026

Rethinking the Valsalva Maneuver During Resistance Exercise: Why Transmural Pressure Matters

Mark J. Haykowsky

Circulation. 2026 June; 10.1161/CIRCULATIONAHA.126.079936

Absolute and workload-indexed exercise blood pressure responses: associations with cardiac output, vascular resistance, and cardiorespiratory fitness in females

Kristel Janssens, Erin J. Howden, Amy M. Mitchell, Leah Wright, Rachel E. Climie, Evelyn B. Parr, Mark J. Haykowsky, Andre La Gerche, Stephen J. Foulkes

American Journal of Physiology-Heart and Circulatory Physiology. 2026 June; 10.1152/ajpheart.00015.2026

From healthy to heart failure in 24 hours: defining the upper limit of exercise-induced cardiac fatigue

Stephen J. Foulkes, Mitchell Anderson, Kristel Janssens, Rhys Beaudry, Andrew Carey, Amy Mitchell, Luke Spencer, Damien Angus, Mark J. Haykowsky, Andre La Gerche

Journal of Applied Physiology. 2026 June; 10.1152/japplphysiol.00140.2026

Acute Aortic Wall Stress Response to Handgrip Exercise in Aneurysmal versus Nondilated Ascending Thoracic Aortas

Michael Sean McMurtry, Mark J. Haykowsky, Rachel J. Skow, Stephen J. Foulkes, Richard B. Thompson, Devyn Walesiak, Christopher Weinkauf, David Niederseer

AORTA. 2026 May; 10.1055/a-2875-3346

Physiological responses to the six-minute walk test in frail/pre-frail patients with cirrhosis awaiting transplantation

Rachel J. Skow, Mark J. Haykowsky, Thomas J. McMurtry, Christofer Cruz, Corey R. Tomczak, Puneeta Tandon

Liver Transplantation. 2026 May; 10.1097/LVT.0000000000000906

Left ventricular systolic function during isometric handgrip exercise and postexercise circulatory occlusion in healthy male and female adults

Natasha G. Boyes, Michael D. Nelson, Mark J. Haykowsky, Cole Elaschuk, Adam M. S. Luchkanych, M. Rafique Khan, Geoffrey Karjala, T. Dylan Olver, Corey R. Tomczak

Journal of Applied Physiology. 2026 May; 10.1152/japplphysiol.00036.2026

Borderline Arrhythmogenic Cardiomyopathy in an Athlete

Simon Wernhart, Martin Halle, Mark J. Haykowsky, Satyam Sarma

JACC: Case Reports. 2026 April; 10.1016/j.jaccas.2026.107837

Acute effects of aerobic exercise on aortic wall stress in thoracic aortic disease

Rachel J. Skow, Stephen J. Foulkes, Richard B. Thompson, Justin Grenier, Nathaniel Moulson, David Niederseer, James McKinny, John Elefteriades, Michael Sean McMurtry, Mark J. Haykowsky

American Journal of Physiology-Heart and Circulatory Physiology. 2026 February; 10.1152/ajpheart.00829.2025

https://pubmed-ncbi-nlm-nih-gov.login.ezproxy.library.ualberta.ca/?term=haykowsky&sort=pubdate&size=200

2026 January;

Progression of Ascending Aortic Dimensions in Masters Endurance Athletes

Nathaniel Moulson, Noah D. Boroditsky, Julien Wiese, Reid A. Mitchell, Mark J. Haykowsky, Stephen J. Foulkes, James Roberts, Saul Isserow, Barbara N. Morrison, James McKinney

JACC: Advances. 2025 October; 10.1016/j.jacadv.2025.102163

Benefits of Cardiac Rehabilitation: Mechanisms to Restore Function and Clinical Impact

Abdulla A. Damluji, Corey R. Tomczak, Stephanie Hiser, Deirdre E. O’Neill, Parag Goyal, Quinn R. Pack, Stephen J. Foulkes, Todd M. Brown, Mark J. Haykowsky, Dale M. Needham, Daniel E. Forman

Circulation Research. 2025 July; 10.1161/CIRCRESAHA.125.325705

Validation of magnetic resonance imaging-derived venous oxygen saturation and oxygen consumption measurements during exercise

Rachel J. Skow, Stephen J. Foulkes, Hendrik Mugele, Dean R. Perkins, Justin S. Lawley, Corey R. Tomczak, Michael D. Nelson, Andre La Gerche, Mark J. Haykowsky, Richard B. Thompson

American Journal of Physiology-Heart and Circulatory Physiology. 2025 June; 10.1152/ajpheart.00134.2025

Musclin and HFpEF: Unlocking Skeletal Muscle Potential to Improve Exercise Tolerance

Stephen J. Foulkes, Michael D. Nelson, Mark J. Haykowsky

Circulation: Heart Failure. 2025 June; 10.1161/CIRCHEARTFAILURE.125.013130

Insights From a 20-Year Follow-Up of the First Heart Transplant Recipient to Complete an Ironman Triathlon

Stephen J. Foulkes, Rachel J. Skow, Andre La Gerche, Wayne J. Tymchak, Mark J. Haykowsky

Circulation: Heart Failure. 2025 March; 10.1161/CIRCHEARTFAILURE.124.012027

Aorta Wall Stress during Exercise in Patients with an Ascending Thoracic Aortic Aneurysm: Insights from a Case Series

Mark J. Haykowsky, Rachel J. Skow, Stephen J. Foulkes, Justin Grenier, John A. Elefteriades, Richard B. Thompson, M. Sean McMurtry

AORTA. 2024 October; 10.1055/a-2558-4266

Lifelong physiology of a former marathon world-record holder: the pros and cons of extreme cardiac remodeling

Stephen J. Foulkes, Mark J. Haykowsky, Peter M. Kistler, Glenn K. McConell, Scott Trappe, Mark Hargreaves, David L. Costill, Andre La Gerche

Journal of Applied Physiology. 2024 September; 10.1152/japplphysiol.00070.2024

Impact of whole-body and skeletal muscle composition on peak oxygen uptake in heart failure: a systematic review and meta-analysis

Veronika Schmid, Stephen J Foulkes, Devyn Walesiak, Jing Wang, Corey R Tomczak, Wesley J Tucker, Siddhartha S Angadi, Martin Halle, Mark J Haykowsky

European Heart Journal Open. 2024 August; 10.1093/ehjopen/oeae082

Physiological determinants of decreased peak leg oxygen uptake in chronic disease: a systematic review and meta-analysis

Stephen J. Foulkes, Peter D. Wagner, Jing Wang, Andre La Gerche, Mark J. Haykowsky

Journal of Applied Physiology. 2024 June; 10.1152/japplphysiol.00918.2023

Determinants of Impaired Peak Oxygen Uptake in Breast Cancer Survivors: JACC: CardioOncology Primer

Stephen J. Foulkes, Mark J. Haykowsky, Todd Li, Jing Wang, Megan Kennedy, Amy A. Kirkham, Richard B. Thompson, D. Ian Paterson, Andre La Gerche, Edith Pituskin

JACC: CardioOncology. 2024 February; 10.1016/j.jaccao.2023.11.005

View additional publications