Ralf Schirrmacher
Contact
Professor, Faculty of Medicine & Dentistry - Oncology Dept
- schirrma@ualberta.ca
- Phone
- (780) 248-1829
- Address
-
2-110 Medical Isotope and Cyclotron Facility
6820 - 116 St NWEdmonton ABT6H 2V8
Overview
Area of Study / Keywords
About
I obtained my PhD from the University of Mainz (Germany) in Nuclear Chemistry in 1999. After a brief postdoctoral stay at the University of Pennsylvania (Research
My research group develops new imaging agents for Positron Emission Tomography (PET) imaging in the field of oncology and neurology. Our current interests are the development of novel radiolabeling strategies for peptide and proteinCourses
CHEM 405 - Special Topics in Chemistry
Prerequisites: a 300- level CHEM course and consent of Instructor; prerequisite courses vary, depending on topic. Course may be repeated for credit, provided there is no duplication of specific topic.
CHEM 669 - Special Topics in Bio-organic Chemistry
Advanced discussion of selected topics in modern bio-organic chemistry, drawn from one or more of the following: (1) natural products and secondary metabolism, (2) nucleic acid chemistry, and (3) organic and biophysical carbohydrate chemistry. Other topics appropriate to the category may also be offered. Course may be repeated for credit, provided there is no duplication of specific topic.
ONCOL 475 - Fundamentals of Radiopharmaceutical Sciences
Practical techniques in the use of radioisotopes in the life sciences. This course focuses on safe handling of radio-isotopes, measurement of radioactivity, performance of radiochemical reactions and the application of radionuclides in life sciences (99mTc-labeling and 18F-labeling). The accompanying seminar provides the necessary background knowledge to engage with the practical challenges of radionuclide handling. Credit cannot be obtained for both ONCOL 475 and 575.
ONCOL 575 - Fundamentals of Radiopharmaceutical Sciences
Practical techniques in the use of radioisotopes in the life sciences. This course focuses on safe handling of radio-isotopes, measurement of radioactivity, performance of radiochemical reactions and the application of radionuclides in life sciences (99mTc-labeling and 18F-labeling). The accompanying seminar provides the necessary background knowledge to engage with the practical challenges of radionuclide handling. Credit cannot be obtained for both ONCOL 475 and 575. Prerequisite: Consent of the Department.
Featured Publications
Bernardes E., Caravan P., van Dam R.M., Deuther-Conrad W., Ellis B., Furumoto S., Guillet B., Huang Y.Y., Jia H., Laverman P., Li Z., Liu Z., Lodi F., Miao Y., Perk L., Schirrmacher R., Vercoullie J., Yang H., Yang M., Yang X., Zhang J., Zhang M.R., Zhu H.
EJNMMI Research. 2022 December; 7 (1):1 10.1186/s41181-022-00162-3
[18F] TRACK, the first PET tracer for imaging of TrkB/C receptors in humans
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022 June;
Radioisotope-loaded microbubbles for cancer imaging and therapy
Nuclear Medicine and Biology. 2022 June;
Reducing protodeboronation using a novelboronic ester in the late-stage copper-mediated radiofluorination
Nuclear Medicine and Biology. 2022 June;
The development of heparanase-targetingradiotracers for PET imaging
Nuclear Medicine and Biology. 2022 June;
Wurzer A., Di Carlo D., Herz M., Richter A., Robu S., Schirrmacher R., Mascarin A., Weber W., Eiber M., Schwaiger M., Wester H.J.
EJNMMI Radiopharmacy and Chemistry. 2021 December; 6 (1):1-15 10.1186/s41181-021-00120-5
Zacherl M.J., Todica A., Wängler C., Schirrmacher R., Hajebrahimi M.A., Pircher J., Li X., Lindner S., Brendel M., Bartenstein P., Massberg S., Brunner S., Lehner S., Hacker M., Huber B.C.
JOURNAL OF NUCLEAR CARDIOLOGY. 2021 December; 28 (6):2965-2975 10.1007/s12350-020-02262-6
Damerow H., Hübner R., Judmann B., Schirrmacher R., Wängler B., Fricker G., Wängler C.
Cancers. 2021 December; 13 (24):6340 10.3390/cancers13246349
Damerow H., Hübner R., Judmann B., Schirrmacher R., Wängler B., Fricker G., Wängler C.
Cancers. 2021 December; 13 (24):6349 10.3390/cancers13246349
Bailey J.J., Wuest M., Wagner M., Bhardwaj A., Wängler C., Wängler B., Valliant J.F., Schirrmacher R., Wuest F.
Journal of Medicinal Chemistry. 2021 November; 64 (21):15671-15689 10.1021/acs.jmedchem.1c00812
Beyer L., Gosewisch A., Lindner S., Völter F., Mittlmeier L.M., Tiling R., Brendel M., Cyran C.C., Unterrainer M., Rübenthaler J., Auernhammer C.J., Spitzweg C., Böning G., Gildehaus F.J., Jurkschat K., Wängler C., Wängler B., Schirrmacher R., Wenter V., Todica A., Bartenstein P., Ilhan H.
EJNMMI. 2021 October; 48 (11):3571-3581 10.1007/s00259-021-05351-x
Lindner S., Rudolf H., Palumbo G., Oos R., Antons M., Hübner R., Bartenstein P., Schirrmacher R., Wängler B., Wängler C.
Bioorganic and Medicinal Chemistry Letters. 2021 September; 48 10.1016/j.bmcl.2021.128241
Bailey J.J., Wuest M., Bojovic T., Kronemann T., Wängler C., Wängler B., Wuest F., Schirrmacher R.
ACS Omega. 2021 August; 6 (33):21741-21754 10.1021/acsomega.1c03315
Unterrainer M., Lindner S., Beyer L., Gildehaus F.J., Todica A., Mittlmeier L.M., Jurkschat K., Wangler C., Wangler B., Schirrmacher R., Tonn J.C., Albert N.L., Bartenstein P., Ilhan H.
Clinical Nuclear Medicine. 2021 August; 46 (8):667-668 10.1097/RLU.0000000000003607
Gower-Fry L., Kronemann T., Dorian A., Pu Y., Jaworski C., Wängler C., Bartenstein P., Beyer L., Lindner S., Jurkschat K., Wängler B., Bailey J.J., Schirrmacher R.
Pharmaceuticals. 2021 July; 14 (7):701 10.3390/ph14070701
Xia Cheng, Ralph Hübner, Valeska von Kiedrowski, Gert Fricker, Ralf Schirrmacher, Carmen Wängler, Björn Wängler
Pharmaceuticals. 2021 June; 14 (6):547 10.3390/ph14060547
Ralph Hübner, Alexa Paretzki, Valeska von Kiedrowski, Marco Maspero, Xia Cheng, Güllü Davarci, Diana Braun, Helen Damerow, Benedikt Judmann, Vasileios Filippou, Clelia Dallanoce, Ralf Schirrmacher, Björn Wängler, Carmen Wängler
Pharmaceuticals. 2021 June; 14 (6):531 10.3390/ph14060531
Unterrainer M, Lindner S, Beyer L, Gildehaus FJ, Todica A, Mittlmeier LM, Jurkschat K, Wängler C, Wängler B, Schirrmacher R, Tonn JC, Albert NL, Bartenstein P, Ilhan H
CLINICAL NUCLEAR MEDICINE. 2021 April; ahead of print 10.1097/RLU.0000000000003607
Malik N., Kornelsen R., McCormick S., Colpo N., Merkens H., Bendre S., Benard F., Sossi V., Schirrmacher R., Schaffer P.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2021 February; 211 10.1016/j.ejmech.2020.113005
Wuest F., Mattingly S.J., Wuest M., Fine E.J., Schirrmacher R., Wuest F.
RSC Medicinal Chemistry. 2021 February; 11 (2):297-306 10.1039/c9md00486f
Wurzer A, Di Carlo D, Herz M, Richter A, Robu S, Schirrmacher R, Mascarin A, Weber W, Eiber M, Schwaiger M, Wester HJ.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021 January; 10.1186/s41181-021-00120-5
Beyer L., Gosewisch A., Lindner S., Völter F., Mittlmeier L.M., Tiling R., Brendel M., Cyran C.C., Unterrainer M., Rübenthaler J., Auernhammer C.J., Spitzweg C., Böning G., Gildehaus F.J., Jurkschat K., Wängler C., Wängler B., Schirrmacher R., Wenter V., Todica A., Bartenstein P., Ilhan H.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021 January; 10.1007/s00259-021-05351-x
Ralf Schirrmacher, Vadim Bernard-Gauthier, Carolin Jaworski, Carmen Wängler, Björn Wängler, Justin Bailey Editors: Dierckx R.A.J.O., Otte A., De Vries E.F.J., Van Waarde A., Luiten P.G.M.
PET and SPECT of Neurobiological Systems. 2021 January; 10.1007/978-3-030-53176-8
Pretze M., von Kiedrowski V., Runge R., Freudenberg R., Hübner R., Davarci G., Schirrmacher R., Wängler C., Wängler B.
Nanomaterials. 2021 January; 11 (1):1-30 10.3390/nano11010138
Von Kiedrowski V., Hübner R., Kail D., Cheng X., Schirrmacher R., Wängler C., Wängler B.
Journal of Materials Chemistry B. 2020 December; 8 (46):10602-10608 10.1039/d0tb01798a
Lindner S., Wängler C., Bailey J.J., Jurkschat K., Bartenstein P., Wängler B., Schirrmacher R.
Nature Protocols. 2020 December; 15 (12):3827-3843 10.1038/s41596-020-00407-y