Ralf Schirrmacher

Professor, Faculty of Medicine & Dentistry - Oncology Dept

Contact

Professor, Faculty of Medicine & Dentistry - Oncology Dept
Email
schirrma@ualberta.ca
Phone
(780) 248-1829
Address
2-110 Medical Isotope and Cyclotron Facility
6820 - 116 St NW
Edmonton AB
T6H 2V8

Overview

Area of Study / Keywords


About

I obtained my PhD from the University of Mainz (Germany) in Nuclear Chemistry in 1999. After a brief postdoctoral stay at the University of Pennsylvania ( I continued research at the University of Mainz as a civil servant until 2007. In 2008 I was appointed Head of Radiochemistry and Director of Cyclotron at the McConnell Brain Imaging Center at the Montreal Neurological Institute (MNI) of McGill University. During my time at McGill I held a Canada Research Chair in Molecular Imaging and Radiochemistry. I am currently an Associate Professor in Oncologic Imaging at the Faculty of Medicine at the MICF and Cross Cancer Center.

Research

My research group develops new imaging agents for Positron Emission Tomography (PET) imaging in the field of oncology and neurology. Our current interests are the development of novel radiolabeling strategies for peptide and protein for cancer imaging as well as introduction of receptor kinase () receptor ligands for oncological and neurological imaging. We furthermore continue our research in nano particle PET platform development. We work with a variety of different radionuclides such as carbon-11, fluorine-18, gallium-68, different radioisotopes of iodine and soon copper-64. We welcome undergraduate- as well as graduate students with a chemistry or pharmacology background to contact us and inquire further information.

Courses

CHEM 405 - Special Topics in Chemistry

Prerequisites: a 300- level CHEM course and consent of Instructor; prerequisite courses vary, depending on topic. Course may be repeated for credit, provided there is no duplication of specific topic.


CHEM 669 - Special Topics in Bio-organic Chemistry

Advanced discussion of selected topics in modern bio-organic chemistry, drawn from one or more of the following: (1) natural products and secondary metabolism, (2) nucleic acid chemistry, and (3) organic and biophysical carbohydrate chemistry. Other topics appropriate to the category may also be offered. Course may be repeated for credit, provided there is no duplication of specific topic.


Browse more courses taught by Ralf Schirrmacher

Featured Publications

Bernardes E., Caravan P., van Dam R.M., Deuther-Conrad W., Ellis B., Furumoto S., Guillet B., Huang Y.Y., Jia H., Laverman P., Li Z., Liu Z., Lodi F., Miao Y., Perk L., Schirrmacher R., Vercoullie J., Yang H., Yang M., Yang X., Zhang J., Zhang M.R., Zhu H.

EJNMMI Research. 2022 December; 7 (1):1 10.1186/s41181-022-00162-3


[18F] TRACK, the first PET tracer for imaging of TrkB/C receptors in humans

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2022 June;


Radioisotope-loaded microbubbles for cancer imaging and therapy

Nuclear Medicine and Biology. 2022 June;


Reducing protodeboronation using a novelboronic ester in the late-stage copper-mediated radiofluorination

Nuclear Medicine and Biology. 2022 June;


The development of heparanase-targetingradiotracers for PET imaging

Nuclear Medicine and Biology. 2022 June;


Wurzer A., Di Carlo D., Herz M., Richter A., Robu S., Schirrmacher R., Mascarin A., Weber W., Eiber M., Schwaiger M., Wester H.J.

EJNMMI Radiopharmacy and Chemistry. 2021 December; 6 (1):1-15 10.1186/s41181-021-00120-5


Zacherl M.J., Todica A., Wängler C., Schirrmacher R., Hajebrahimi M.A., Pircher J., Li X., Lindner S., Brendel M., Bartenstein P., Massberg S., Brunner S., Lehner S., Hacker M., Huber B.C.

JOURNAL OF NUCLEAR CARDIOLOGY. 2021 December; 28 (6):2965-2975 10.1007/s12350-020-02262-6


Damerow H., Hübner R., Judmann B., Schirrmacher R., Wängler B., Fricker G., Wängler C.

Cancers. 2021 December; 13 (24):6340 10.3390/cancers13246349


Damerow H., Hübner R., Judmann B., Schirrmacher R., Wängler B., Fricker G., Wängler C.

Cancers. 2021 December; 13 (24):6349 10.3390/cancers13246349


Bailey J.J., Wuest M., Wagner M., Bhardwaj A., Wängler C., Wängler B., Valliant J.F., Schirrmacher R., Wuest F.

Journal of Medicinal Chemistry. 2021 November; 64 (21):15671-15689 10.1021/acs.jmedchem.1c00812


Beyer L., Gosewisch A., Lindner S., Völter F., Mittlmeier L.M., Tiling R., Brendel M., Cyran C.C., Unterrainer M., Rübenthaler J., Auernhammer C.J., Spitzweg C., Böning G., Gildehaus F.J., Jurkschat K., Wängler C., Wängler B., Schirrmacher R., Wenter V., Todica A., Bartenstein P., Ilhan H.

EJNMMI. 2021 October; 48 (11):3571-3581 10.1007/s00259-021-05351-x


Lindner S., Rudolf H., Palumbo G., Oos R., Antons M., Hübner R., Bartenstein P., Schirrmacher R., Wängler B., Wängler C.

Bioorganic and Medicinal Chemistry Letters. 2021 September; 48 10.1016/j.bmcl.2021.128241


Bailey J.J., Wuest M., Bojovic T., Kronemann T., Wängler C., Wängler B., Wuest F., Schirrmacher R.

ACS Omega. 2021 August; 6 (33):21741-21754 10.1021/acsomega.1c03315


Unterrainer M., Lindner S., Beyer L., Gildehaus F.J., Todica A., Mittlmeier L.M., Jurkschat K., Wangler C., Wangler B., Schirrmacher R., Tonn J.C., Albert N.L., Bartenstein P., Ilhan H.

Clinical Nuclear Medicine. 2021 August; 46 (8):667-668 10.1097/RLU.0000000000003607


Gower-Fry L., Kronemann T., Dorian A., Pu Y., Jaworski C., Wängler C., Bartenstein P., Beyer L., Lindner S., Jurkschat K., Wängler B., Bailey J.J., Schirrmacher R.

Pharmaceuticals. 2021 July; 14 (7):701 10.3390/ph14070701


Xia Cheng, Ralph Hübner, Valeska von Kiedrowski, Gert Fricker, Ralf Schirrmacher, Carmen Wängler, Björn Wängler

Pharmaceuticals. 2021 June; 14 (6):547 10.3390/ph14060547


Ralph Hübner, Alexa Paretzki, Valeska von Kiedrowski, Marco Maspero, Xia Cheng, Güllü Davarci, Diana Braun, Helen Damerow, Benedikt Judmann, Vasileios Filippou, Clelia Dallanoce, Ralf Schirrmacher, Björn Wängler, Carmen Wängler

Pharmaceuticals. 2021 June; 14 (6):531 10.3390/ph14060531


Unterrainer M, Lindner S, Beyer L, Gildehaus FJ, Todica A, Mittlmeier LM, Jurkschat K, Wängler C, Wängler B, Schirrmacher R, Tonn JC, Albert NL, Bartenstein P, Ilhan H

CLINICAL NUCLEAR MEDICINE. 2021 April; ahead of print 10.1097/RLU.0000000000003607


Malik N., Kornelsen R., McCormick S., Colpo N., Merkens H., Bendre S., Benard F., Sossi V., Schirrmacher R., Schaffer P.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2021 February; 211 10.1016/j.ejmech.2020.113005


Wuest F., Mattingly S.J., Wuest M., Fine E.J., Schirrmacher R., Wuest F.

RSC Medicinal Chemistry. 2021 February; 11 (2):297-306 10.1039/c9md00486f


Wurzer A, Di Carlo D, Herz M, Richter A, Robu S, Schirrmacher R, Mascarin A, Weber W, Eiber M, Schwaiger M, Wester HJ.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021 January; 10.1186/s41181-021-00120-5


Beyer L., Gosewisch A., Lindner S., Völter F., Mittlmeier L.M., Tiling R., Brendel M., Cyran C.C., Unterrainer M., Rübenthaler J., Auernhammer C.J., Spitzweg C., Böning G., Gildehaus F.J., Jurkschat K., Wängler C., Wängler B., Schirrmacher R., Wenter V., Todica A., Bartenstein P., Ilhan H.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021 January; 10.1007/s00259-021-05351-x


Ralf Schirrmacher, Vadim Bernard-Gauthier, Carolin Jaworski, Carmen Wängler, Björn Wängler, Justin Bailey Editors: Dierckx R.A.J.O., Otte A., De Vries E.F.J., Van Waarde A., Luiten P.G.M.

PET and SPECT of Neurobiological Systems. 2021 January; 10.1007/978-3-030-53176-8


Pretze M., von Kiedrowski V., Runge R., Freudenberg R., Hübner R., Davarci G., Schirrmacher R., Wängler C., Wängler B.

Nanomaterials. 2021 January; 11 (1):1-30 10.3390/nano11010138


Von Kiedrowski V., Hübner R., Kail D., Cheng X., Schirrmacher R., Wängler C., Wängler B.

Journal of Materials Chemistry B. 2020 December; 8 (46):10602-10608 10.1039/d0tb01798a


Lindner S., Wängler C., Bailey J.J., Jurkschat K., Bartenstein P., Wängler B., Schirrmacher R.

Nature Protocols. 2020 December; 15 (12):3827-3843 10.1038/s41596-020-00407-y