Bradley Kerr

Area of Study / Keywords

Neuroscience

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About

Dr. Bradley Kerr is currently appointed as Associate Professor (UAH), Adjunct Assistant Professor (Pharmacology) in the Department of Anesthesiology & Pain Medicine in the Faculty of Medicine & Dentistry.

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Research

The development of chronic pain after spinal cord injury or in diseases such as multiple sclerosis (MS) is a major clinical concern. The main focus of research in my laboratory is aimed at addressing the cellular mechanisms that generate neuropathic pain in these conditions. My research uses two primary animal models: a clinically relevant spinal contusion injury model and a mouse model of autoimmune demyelination that resembles MS, experimental autoimmune encephalomyelitis (EAE). My research aims to understand the specific pathways and cellular changes that arise in response to direct trauma or in chronic disease states that may promote the development of neuropathic pain. The lab employs a number of different strategies that include analysis at the cell and molecular levels, as well as systems level approaches to address this complex biological problem. 

Funding Sources 

• The Multiple Sclerosis Society of Canada
• National Sciences and Engineering Research Council (NSERC)
• Canadian Foundation for Innovation
• University Hospital Fund Lab Staff
  

Dworsky-Fried Z., Faig C.A., Vogel H.A., Kerr B.J., Taylor A.M.W.

PAIN. 2022 January; 163 (1):E49-E61 10.1097/j.pain.0000000000002307

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Maguire A.D., Bethea J.R., Kerr B.J.

Frontiers in Neurology. 2021 December; 12 10.3389/fneur.2021.780876

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Dworsky-Fried Z., Chadwick C.I., Kerr B.J., Taylor A.M.W.

Frontiers in Neuroscience. 2021 September; 15 10.3389/fnins.2021.741503

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Hammond B.P., Manek R., Kerr B.J., Macauley M.S., Plemel J.R.

GLIA. 2021 January; 10.1002/glia.24047

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Zia S., Rawji K.S., Michaels N.J., Burr M., Kerr B.J., Healy L.M., Plemel J.R.

Frontiers in Immunology. 2020 November; 11 10.3389/fimmu.2020.588021