Designed to provide graduate students in the Neuroscience program a comprehensive overview on neurobiology of various neurodegenerative disorders. Both clinical and basic science aspects of major neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington disease, Prion disease, Motor neuron disease (MND), Frontotemporal Dementia, Multiple Sclerosis and Chronic Traumatic Encephalopathy will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 411 or 511 but not both.