Designed to provide graduate students in the Neuroscience program a comprehensive overview of the neurobiology of normal aging and the cellular/molecular phenomena that may underlie various age-related neurodegenerative diseases. Aspects of neuronal and glial changes during the normal aging process will be covered. We also intend to include a video presentation of patients with neurodegenerative disorders to outline the impact of cellular/molecular changes on major clinical and psychological features. In addition, papers on the most recent developments in the field of aging research have been integrated into the course. Prerequisites: NEURO 375 or PMCOL 371 or ZOOL 342 or consent from course coordinator. Credit may be obtained for either NEURO 410 or 510 but not both.