An introduction to the structure and function of the immune system. Topics include the ontogeny of immune structures and cells, the generation of B and T cell receptor diversity, antigens and antibodies, clonal selection and expansion, MHC restriction, self tolerance and cytokines. Discussion of infectious disease, vaccines, and immunity will be used to synthesize these topics into a unified conceptual framework. Prerequisites: AUBIO 274 or AUBIO 374 (2022). Note: Credit may be obtained for only one of AUBIO 371 (2021) and AUBIO 471.