Leo Spyracopoulos

Professor, Faculty of Medicine & Dentistry - Biochemistry Dept


Professor, Faculty of Medicine & Dentistry - Biochemistry Dept
(780) 492-2417
416A Medical Sciences Building
8613 - 114 St NW
Edmonton AB
T6G 2H7


BIOCH 420 - Proteins: Structure, Function, and Regulation

Principles of protein structure, function, and dynamics, with an introduction to force fields used in modern molecular dynamics. Focus topics include an introduction to intrinsically disordered proteins and their role in misfolding diseases, the structural biology, ligand binding, and mechanisms of membrane bound enzymes, and mechanisms underlying the regulation of protein function and enzymes involved in cell signaling. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 520).

Fall Term 2021
BIOCH 520 - Protein Chemistry, Structure, and Function

Protein chemistry and purification. The intra- and intermolecular forces that determine protein structure. Principles of protein folding and dynamics. Enzyme mechanisms and ligand binding interactions. Prerequisites: BIOCH 320, or BIOCH 203 and 205, all with a minimum grade of B- or consent of Department. Lectures are the same as for BIOCH 420, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 420.

Fall Term 2021

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