BIOCH 420 - Proteins: Structure, Function, and Regulation

3 units (fi 6)(EITHER, 3-0-0)

Faculty of Medicine and Dentistry

Principles of protein structure, function, and dynamics, with an introduction to force fields used in modern molecular dynamics. Focus topics include an introduction to intrinsically disordered proteins and their role in misfolding diseases, the structural biology, ligand binding, and mechanisms of membrane bound enzymes, and mechanisms underlying the regulation of protein function and enzymes involved in cell signaling. Prerequisites: BIOCH 320, with a minimum grade of B- or consent of Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 520).