Physical properties of biological macromolecules and macromolecular assemblies; biopolymer folding; ligand binding and allostery; lipid membranes; cellular electricity and nerve conduction; models of molecular motors; stochasticity in biology; numerical and experimental techniques in biophysics; synthetic biology. Prerequisites: MATH 209 or 215 or 315 or 317 or MA PH 351, MATH 201/334/336 or MA PH 251, BIOPH 201, PHYS 234, PHYS 230/281, PHYS 310.