Integrated exploration of concepts and research methods pertaining to gastrointestinal physiology, gastrointestinal disorders, and the role of the commensal microbiota in health and disease of humans and animals. Tools to modify the function of the intestinal microflora for prevention or treatment of disease by administration of probiotic bacteria or by administration of prebiotics. Offered in odd-numbered years. Prerequisites: (*3 Microbiology or *3 Immunology) and consent of instructor. Offered jointly by the Departments of Agricultural, Food and Nutritional Science and Medicine. [Agricultural, Food and Nutritional Science].