This course will focus on concepts and mechanisms of microbial pathogenesis by discussing a combination of classic and current papers. Essentially a paper dissection course, emphasis will be on experimental approaches, their strengths and limitations. Student-run seminars will be used to facilitate interactive learning. Lectures and seminars are the same as for MMI 405 but there will be an additional requirement of a written research proposal. This course may not be taken if credit has already been obtained in MMI 405. Consent of Department required.