The course explores episodic, chronic, and conjunct health alterations and the related pharmacological concepts. Main topics include neurology, exploration of more complex alterations such as shock, trauma, congenital disorders, and lifespan considerations. The focus is on more complex disorders of function through application of foundational knowledge of pathophysiology and pharmacology, and more robust critical thinking. Evidence-informed nursing practice is central to the course. Aligns with concepts from NURS 220/SC INF 223 and NURS/SC INF 221 intentional clinical learning activities. Note: Available only to nursing students in the Collaborative/Honors Program and Bilingual Program. Prerequisite: NURS 206. Credit may be obtained for only one of NURS 216, or NURS 206 and NURS 207. Credit is required for both NURS 206 and NURS 207.