BIOCH 310 - Bioenergetics and Metabolism

★ 3 (fi 6)(EITHER, 3-0-0)

This course is designed to enable rigorous study of the molecular mechanisms in bioenergetics and metabolism. It covers: the principles of bioenergetics; the reactions and pathways of carbohydrate, lipid, and nitrogen metabolism, and their regulation; oxidative phosphorylation; the integration and hormonal regulation of mammalian metabolism. Prerequisites: BIOCH 200, CHEM 102 (or SCI 100) and CHEM 263 with a minimum GPA of 2.70 for these three courses. In the case of over-subscription, preference will be given to students enrolled in programs with a requirement for this course.

BIOCH 410 - Signal Transduction

★ 3 (fi 6)(EITHER, 3-0-0)

Principles of the biochemistry of cell communication and signal transduction through receptor activation, generation of second messengers, control of protein modifications and regulation of the cell cycle. The course emphasizes mechanisms responsible for the regulation of cell migration, division and death with an emphasis on cancer. Prerequisites: BIOCH 310, 320 and 330, all with a minimum grade of B-, or consent of the Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 510).

BIOCH 415 - Metabolic Modifications in Health and Disease

★ 3 (fi 6)(EITHER, 3-0-0)

This course introduces students to adaptive and pathological changes in human metabolic pathways. The course will cover various situations which alter the 'normal' function of the metabolic pathways, such as lifestyle modifications (e.g. exercise, diet), starvation, cancer, diabetes, aging and neurodegenerative disorders, immune diseases, and mitochondrial diseases. Prerequisite(s): BIOCH 310 with a minimum grade of B-. This course is restricted to students in an Honors or Major Program in Biochemistry, students in other programs may be admitted subject to availability and with the consent of the Department.

BIOCH 510 - Signal Transduction

★ 3 (fi 6)(EITHER, 3-0-0)

Principles of the biochemistry of cell communication and signal transduction through receptor activation, generation of second messengers, control of protein modifications and regulation of the cell cycle. The course emphasizes mechanisms responsible for the regulation of cell migration, division and death with an emphasis on cancer. Prerequisites: BIOCH 310, 320 and 330, all with a minimum grade of B-, or consent of the Department. Lectures are the same as for BIOCH 410, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 410.