CELL 403 - Principles of Medical Genetics

3 units (fi 6)(FIRST, 3-0-0)

The rapid expansion of our understanding of the human genome has created new, exciting possibilities to understanding the root causes of human disease and improve health. However, this also leads to real and potential problems - both ethical and practical. This senior level undergraduate course will consist of four modules each covering different aspects of the scientific theory underlying the practice of Medical Genetics. Topics will include core concepts in human genomics, developmental genetics, genetic variation, Mendelian and non-Mendelian traits, Mendelian disease as examples of key genomic concepts, methodologies that allow for screening of genetic disease and the theory supporting the practice of genetic counselling. This course will be based on didactic understanding of the topics and draw upon examples from the expertise of the instructors. Prerequisites CELL 201 or BIOL 201, 300 level course in CELL or GENET or consent of the Department. Note: Not to be taken by students with credit in MDGEN 403. In addition, not available to students currently enrolled in MDGEN 403.

MDGEN 403 - Principles of Medical Genetics

3 units (fi 6)(FIRST, 3-0-0)

The rapid expansion of our understanding of the human genome has created new, exciting possibilities to understanding the root causes of human disease and improve health. However, this also leads to real and potential problems - both ethical and practical. This senior level undergraduate course will consist of four modules each covering different aspects of the scientific theory underlying the practice of Medical Genetics. Topics will include core concepts in human genomics, developmental genetics, genetic variation, Mendelian and non- Mendelian traits, Mendelian disease as examples of key genomic concepts, methodologies that allow for screening of genetic disease and the theory supporting the practice of genetic counselling. This course will be based on didactic understanding of the topics and draw upon examples from the expertise of the instructors. Prerequisites CELL 201 or BIOL 201, 300 level course in CELL or GENET or consent of the Department. Note: Not to be taken by students with credit in CELL 403. In addition, not available to students currently enrolled in CELL 403.

MDGEN 601 - Selected Topics in Medical Genetics

3 units (fi 6)(EITHER, 1-2S-0)

A directed reading and seminar course based on papers taken from the recent literature of medical genetics. The course consists of lectures on a specific topic in medical genetics and oral presentations of the current literature by students. Selected topics vary so that students may take the same course but examining a different topic for additional credit. Prerequisite: consent of the Department of Medical Genetics. Credit may only be obtained in one of MDGEN 401 or MDGEN 601.