Frank Wuest

Professor, Faculty of Medicine & Dentistry - Oncology Dept
Chair, Faculty of Medicine & Dentistry - Oncology Dept
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No past terms No future terms

Winter Term 2024 (1860)

BIOCH 410 - Signal Transduction

★ 3 (fi 6)(EITHER, 3-0-0)

Principles of the biochemistry of cell communication and signal transduction through receptor activation, generation of second messengers, control of protein modifications and regulation of the cell cycle. The course emphasizes mechanisms responsible for the regulation of cell migration, division and death with an emphasis on cancer. Prerequisites: BIOCH 310, 320 and 330, all with a minimum grade of B-, or consent of the Department. This course is intended for students in Honors or Specialization in Biochemistry. Students in other programs may be admitted subject to availability and with the consent of the Department. Graduate students may not register for credit (see BIOCH 510).

LECTURE B1 (12836)

2024-01-08 - 2024-04-12
MWF 09:00 - 09:50 (ECHA 2-131)



BIOCH 510 - Signal Transduction

★ 3 (fi 6)(EITHER, 3-0-0)

Principles of the biochemistry of cell communication and signal transduction through receptor activation, generation of second messengers, control of protein modifications and regulation of the cell cycle. The course emphasizes mechanisms responsible for the regulation of cell migration, division and death with an emphasis on cancer. Prerequisites: BIOCH 310, 320 and 330, all with a minimum grade of B-, or consent of the Department. Lectures are the same as for BIOCH 410, but with additional assignments and evaluation appropriate to graduate studies. This course may not be taken for credit if credit has already been obtained in BIOCH 410.

LECTURE B1 (12837)

2024-01-08 - 2024-04-12
MWF 09:00 - 09:50 (ECHA 2-131)



ONCOL 520 - Tumor Biology

★ 3 (fi 6)(SECOND, 3-0-0)

The course will provide an introduction to the basic science of oncology. Topics to be covered comprise: the genetic basis of cancer, including the role of proto-oncogenes and tumor suppressor genes; mechanisms of carcinogenesis and radiation-sensitivity, including DNA repair and cell cycle control; the molecular basis of tumor metastasis, including tumor cell invasion, extravasation and dormancy; the role of inflammation in cancer initiation and progression; angiogenesis; cancer genetics, and epigenetics; cell signaling; experimental therapeutics; cancer stem cells; drug-resistance; metabolism and palliation. Course offered in alternate (even-numbered) years. Prerequisites: BIOCH 200, and one of the following: BIOCH 320 or 330 or ONCOL 320.

LECTURE B1 (17722)

2024-01-08 - 2024-04-12
TR 14:00 - 15:20 (ECHA 1-490)

2024-01-16 - 2024-01-18
T 14:00 - 15:20 (ED 107)