Physical principles important to the operation of biological systems. Biological applications of free energy, entropy, random walks, and diffusion; dynamics at low Reynolds number; cooperativity and 2-state systems; structural self-assembly; kinetic modeling; molecular motors and enzymes; membranes and potentials; genetic networks; sequences and evolution. Prerequisites: MATH 100/114/117/134/144, PHYS 124/144 or EN PH131. PHYS 126/130/146 recommended.