This course will introduce the student to common and advanced methods in bioinformatics. In a mix of lectures and hands-on computer sessions, the student will solve realistic biological questions in the areas of sequence analysis, distant homology detection, phylogeny, correlating sequence to structure, protein structure analysis, and genomics. The student will obtain a thorough understanding of bioinformatics methods, but the focus is on application of methods in the context of molecular biology research rather than studying details of the algorithms or computer programming. Prerequisite: consent of instructor. BIOCH 320 or 330 highly recommended. Priority given to senior students in the IMIN program. (Offered jointly by the Departments of Biological Sciences and Medical Microbiology and Immunology). [Biological Sciences].