MED 504 - Evolutionary Parasitology and Cell Biology

★ 3 (fi 6)(EITHER, 3-0-0)

Faculty of Medicine and Dentistry

Eukaryotic microbial parasites cause diseases of major global health importance, including Malaria, Amoebic Dysentery, and Giardiasis. This course examines the cellular diversity of such parasites, framing it in an evolutionary context to examine not only the span of how these cells function but how they arose. Starting by surveying how various parasites fit in the overall diversity of eukaryotes, the course then examines the variation observed in different cellular systems including the nucleus, endomembrane system, mitochondria and plastids. Each organelle will be explored from morphological, genomic and evolutionary perspectives, with emphasis on critical review of literature (mock article reviews) and leading discussions on constructive analysis of data. Offered in alternating years. Prerequisites: Consent of instructor is required. May not be taken if credit for MED 404 has been obtained.

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