This advanced microbiology course will cover selected topics of life in extreme environments, with particular emphasis on diversity, evolutionary and physiological adaptations, methodology for studying extreme environments, the effective limits of life, implications for biogeochemical cycling, and astrobiology. Examples of adaptation to specific environments will be the focus of student projects. Oral presentations required. Lectures are the same as for MICRB 423, but with an additional assignment and evaluation appropriate to graduate studies. Prerequisites: consent of instructor. MICRB 423 and 523 cannot both be taken for credit.